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CLINICAL_TRIALS research · 2025-10-06

Clinical Trial Update: Chimeric Antigen Receptor (CAR) T Cells With a Chlorotoxin Tumor-Targeting Domain for the Treatment of MMP2+ Recurrent or Progressive Glioblastoma [Phase 1]

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Summary

Phase 1 study of chlorotoxin-targeted CAR T cells targeting MMP2 in patients with recurrent glioblastoma and other recurrent gliomas. The trial is currently act…

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Diseases / indications

Drugs mentioned

  • Chlorotoxin-targeted CAR T cells for MMP2+ glioblastoma

Snippet

Sponsor: City of Hope Medical Center | Conditions: Recurrent Glioblastoma, Recurrent Malignant Glioma | Phase 1 | Status: ACTIVE_NOT_RECRUITING