Glioblastoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy [Phase 1]
A Phase 1 clinical trial is evaluating focused ultrasound to disrupt the blood-brain barrier in high-grade glioma patients undergoing standa…
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CLINICAL_TRIALS withdrawal · 2025-09-16Clinical Trial Update: SurVaxM Expanded Access Protocol
The expanded access protocol for SurVaxM in glioblastoma is no longer available.
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Glioma Adaptive Radiotherapy With Development of an Artificial Intelligence Workflow [Phase 2]
Phase 2 clinical trial update for glioma using adaptive radiotherapy guided by an artificial intelligence workflow; the study is not yet rec…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Study of DSP-0390 in Patients With Recurrent High-Grade Glioma [EARLY_Phase 1]
DSP-0390 is being studied in an early-phase Phase 1 trial for recurrent high-grade glioma, including glioblastoma, and the study is currentl…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Combined Treatment of Patients With Newly Diagnosed Glioblastoma Using the Xoft® Axxent® Electronic Brachytherapy (eBx®) System for Intraoperative Balloon Electronic Brachytherapy [Phase 1]
An early-phase Phase 1 study evaluating the use of the Xoft Axxent electronic brachytherapy system for intraoperative balloon brachytherapy …
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: MEDICO-ECONOMIC EVALUATION OF SURGERY GUIDED BY FLUORESCENCE FOR THE OPTIMIZATION OF RESECTION OF GLIOBLASTOMAS [Phase 3]
Phase 3 trial assessing medico-economic value of fluorescence-guided surgery to optimize glioblastoma resection has completed.
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: A Study to Better Understand the Biological and Molecular Mechanisms Involved in Glioblastoma Recurrence and Progression
This clinical trial aims to investigate the biological and molecular mechanisms underlying glioblastoma recurrence and progression.
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Evaluating the Expression Levels of MicroRNA-10b in Patients With Gliomas
The clinical trial investigating microRNA-10b expression in glioma patients has been terminated.
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: A Dose-escalation Clinical Study of Intraoperative Photodynamic Therapy of Glioblastoma [Phase 1, Phase 2]
Dose-escalation Phase 1/2 clinical trial evaluating intraoperative photodynamic therapy for glioblastoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma [EARLY_Phase 1]
This update describes an early-phase window-of-opportunity trial of Troriluzole for recurrent IDH-wild-type glioblastoma, currently recruiti…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Safety and Immunogenicity of Personalized Genomic Vaccine and Tumor Treating Fields (TTFields) to Treat Glioblastoma [Phase 1]
Phase 1 clinical trial evaluating the safety and immunogenicity of a Personalized Genomic Vaccine in combination with Tumor Treating Fields …
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Ferumoxytol MRI in Assessing Response to Pembrolizumab in Patients With Glioblastoma [Phase 2]
Phase 2 clinical trial update evaluating ferumoxytol-enhanced MRI to monitor pembrolizumab response in glioblastoma; the study was terminate…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Safety and Tolerability of Carboxyamidotriazole Orotate (CTO) in Solid Tumors or With Temodar® in Glioblastoma or Other Recurrent Malignant Gliomas or in Combination With Temodar® and Radiation Therapy for Patients With Newly Diagnosed Glioblastoma and Malignant Gliomas [Phase 1]
A Phase 1 study reports on the safety and tolerability of Carboxyamidotriazole Orotate (CTO) in solid tumors and in combination with temozol…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: FearLess in NeuroOncology [NA]
Clinical trial update for FearLess in NeuroOncology indicates the study is currently recruiting for patients with glioblastoma and other pri…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: A Multicenter, Prospective Study for Glioblastoma Patients
This document provides an update on a multicenter, prospective trial for patients with glioblastoma. The study is currently not recruiting.
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: A Study to Evaluate the Safety, Tolerability and Efficacy of RZ-001 With Valganciclovir (VGCV) in Subjects With Glioblastoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the safety, tolerability and efficacy of RZ-001 in combination with valganciclovir for glioblastoma…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: GammaTile and Stupp in Newly Diagnosed GBM [Phase 4]
Phase 4 clinical trial update on the use of GammaTile in combination with the Stupp regimen for newly diagnosed glioblastoma, with the trial…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression [Phase 2]
A Phase 2 safety study evaluating VAL-083 in combination with radiotherapy for newly diagnosed glioblastoma with unmethylated MGMT expressio…
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM [Phase 3]
DelMar Pharmaceuticals' VAL-083 Phase 3 trial for recurrent glioblastoma (after temozolomide and bevacizumab) has been terminated.
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma [Phase 1, Phase 2]
Phase 1/2 trial assessing a PD-1 inhibitor combined with stereotactic radiation for recurrent glioblastoma; the study is currently recruitin…
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: A Study of Abemaciclib in Recurrent Glioblastoma [Phase 2]
Results from a Phase 2 study of abemaciclib in recurrent glioblastoma have been posted.
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Chlorpromazine and Standard of Care in Glioblastoma [Phase 1]
Phase 1 trial evaluating chlorpromazine in combination with standard of care for glioblastoma has completed.
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma [EARLY_Phase 1]
Early-phase study evaluating the use of 18F-FDOPA PET imaging to plan surgery and radiation therapy for adults with newly diagnosed malignan…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Study of VAL-083 in Patients With MGMT Unmethylated, Bevacizumab-naive Glioblastoma in the Adjuvant or Recurrent Setting [Phase 2]
VAL-083 (dianhydrogalactitol) is being studied in MGMT unmethylated, bevacizumab-naive glioblastoma patients in the adjuvant or recurrent se…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Safety Study of VAL-083 in Patients With Recurrent Malignant Glioma [Phase 1, Phase 2]
Kintara Therapeutics completed a Phase 1/2 safety study of VAL-083 in patients with recurrent malignant glioma, including glioma and gliobla…