Germ Cell Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-23Clinical Trial Results: Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors [Phase 2]
Phase 2 clinical trial assessing memantine to prevent cognitive late effects in children receiving cranial radiation for localized brain tum…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors [Phase 1]
Phase 1 clinical trial evaluating B7-H3–specific CAR T cell therapy delivered locoregionally for diffuse intrinsic pontine glioma/diffuse mi…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: A Study of DS-9606a in Patients With Advanced Solid Tumors [Phase 1]
A phase 1 study of DS-9606a in patients with advanced, metastatic cancer, including germ cell tumor, was terminated.
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas [Phase 1]
Phase 1 study evaluating CD45RA+ depleted haploidentical stem cell transplantation in children with relapsed or refractory solid tumors and …
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: CD30 CAR for CD30+ NSGCT [Phase 2]
Phase 2 clinical trial evaluating CD30-targeted CAR-T cell therapy for CD30-positive nonseminomatous germ cell tumors has completed.
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors [Phase 1]
Phase 1 trial evaluating locoregional EGFR806-specific CAR T cells for EGFR-positive pediatric CNS tumors. The study status is completed.
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Clinical Study of Chemotherapy in the Treatment of Recurrent/Refractory Yolk Sac Tumor in Children [Phase 2, Phase 3]
A pediatric trial evaluating chemotherapy for recurrent or refractory yolk sac tumor has completed Phase 2 and Phase 3 studies.
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Thalidomide Combined With Chemotherapy in the Treatment of Relapsed or Refractory Yolk Sac Tumor [Phase 2]
Phase 2 trial evaluating thalidomide combined with chemotherapy for relapsed or refractory yolk sac tumor and other germ cell tumors has bee…
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Role of Axumin PET Scan in Germ Cell Tumor
This clinical trial evaluated the role of Axumin PET imaging in germ cell tumors, including testicular cancer. The study status is completed…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Symptom Management for YA Cancer Survivors [NA]
A completed clinical trial (NCT04035447) examining symptom management for young adult cancer survivors with results posted in 2025.
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Olaparib as Salvage Treatment for Cisplatin-resistant Germ Cell Tumor [Phase 2]
A Phase 2 clinical trial evaluating olaparib as salvage therapy for cisplatin-resistant germ cell tumors has completed, assessing safety and…
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients with Relapsed or Refractory Germ Cell Tumors [Phase 3]
This entry describes a Phase 3 trial comparing standard-dose versus high-dose combination chemotherapy with stem cell transplant for relapse…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors [Phase 1]
Phase 1 trial completion evaluating MR-guided High Intensity Focused Ultrasound (HIFU) for relapsed or refractory pediatric solid tumors, in…
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic [Phase 2]
Phase 2 study of pembrolizumab in patients with rare, unresectable or metastatic solid tumors; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-06-14Clinical Trial Update: A Novel Single Arm Phase II Study for Relapsed Germ Cell Tumours With Poor Prognosis [Phase 2]
Single-arm Phase II trial evaluating a novel therapy for relapsed germ cell tumors with poor prognosis has completed.
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: A Pilot RCT of the PRISM Intervention for AYAs With Cancer [Phase 2]
pilot randomized Phase 2 trial evaluating the PRISM intervention for adolescents and young adults with cancer, completed.
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CLINICAL_TRIALS trial_result · 2023-10-04Clinical Trial Update: Disulfiram and Cisplatin in Refractory TGCTs. [Phase 2]
Phase 2 clinical trial evaluating disulfiram in combination with cisplatin for refractory germ cell tumors has completed.
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CLINICAL_TRIALS trial_result · 2023-07-13Clinical Trial Update: Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors [Phase 2]
A Phase 2 clinical trial evaluated memantine for preventing cognitive late effects in pediatric patients undergoing cranial radiation therap…
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CLINICAL_TRIALS trial_result · 2021-11-10Clinical Trial Update: A Study to Assess the Safety and Efficacy of ASP1650, a Monoclonal Antibody Targeting Claudin 6 (CLDN6), in Male Subjects With Incurable Platinum Refractory Germ Cell Tumors [Phase 2]
Phase 2 study evaluating ASP1650, a monoclonal antibody targeting Claudin 6, in men with incurable platinum-refractory germ cell tumors has …
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CLINICAL_TRIALS trial_result · 2021-10-26Clinical Trial Update: Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating melphalan, carboplatin, mannitol, and sodium thiosulfate for recurrent or progressive central nervous sy…
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CLINICAL_TRIALS trial_result · 2021-06-07Clinical Trial Update: Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors [Phase 3]
Phase 3 trial evaluating combination chemotherapy for stage II or stage III germ cell tumors has completed enrollment and posted results. Th…
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CLINICAL_TRIALS trial_result · 2020-12-10Clinical Trial Update: Study of Brentuximab Vedotin And Bevacizumab In Refractory CD-30 Positive Germ Cell Tumors [Phase 2]
Phase 2 study investigating brentuximab vedotin with bevacizumab in refractory CD-30 positive germ cell tumors was terminated; results poste…
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CLINICAL_TRIALS trial_result · 2020-08-07Clinical Trial Update: First Line TIP in Poor Prognosis TGCTs. [Phase 2]
Phase 2 clinical trial update evaluating first-line TIP regimen in poor prognosis germ cell tumors has completed.
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CLINICAL_TRIALS trial_result · 2019-11-26Clinical Trial Update: Brentuximab Vedotin in Relapsed/Refractory Germ Cell Tumors [Phase 2]
Phase 2 trial of brentuximab vedotin in relapsed/refractory germ cell tumors was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-02-26Clinical Trial Update: A Phase II Study of Sirolimus and Erlotinib in Recurrent/Refractory Germ Cell Tumors [Phase 2]
Phase II study of sirolimus and erlotinib in relapsed/recurrent germ cell tumors was terminated; results posted in 2019.