Germ Cell Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-23Clinical Trial Results: Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors [Phase 2]
Phase 2 clinical trial assessing memantine to prevent cognitive late effects in children receiving cranial radiation for localized brain tum…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Tumor-Lymph Node Mapping
Clinical trial from the University of Rochester is actively recruiting to study tumor-lymph node mapping in pediatric solid tumors. The cond…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies [Phase 1]
Phase 1 trial at New York Medical College evaluating vorinostat in combination with chemotherapy for relapsed/refractory solid tumors and CN…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study of ZW251 in Participants With Advanced Solid Tumors [Phase 1]
This Phase 1 trial update notes a study of ZW251 in participants with advanced solid tumors, including hepatocellular carcinoma, non-small c…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors [Phase 1]
Phase 1 clinical trial evaluating B7-H3–specific CAR T cell therapy delivered locoregionally for diffuse intrinsic pontine glioma/diffuse mi…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors [Phase 3]
A Phase 3 clinical trial update on active surveillance followed by BEP-like regimens (bleomycin, etoposide, with carboplatin or cisplatin) i…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study to Test How Well Different Doses of BI 3820768 Are Tolerated by People With Advanced Cancer (Solid Tumours) [Phase 1]
A Phase 1 trial to assess tolerability of different doses of BI 3820768 in adults with advanced relapsed or refractory germ cell tumors, end…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: A Study of DS-9606a in Patients With Advanced Solid Tumors [Phase 1]
A phase 1 study of DS-9606a in patients with advanced, metastatic cancer, including germ cell tumor, was terminated.
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors [Phase 1]
Phase 1 safety and tolerability study of XmAb541 in advanced solid tumors is currently recruiting, investigating ovarian cancer, endometrial…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Study of miRNA 371 in Patients With Germ Cell Tumors
SWOG Cancer Research Network is studying miRNA-371 in patients with germ cell tumors; the trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Proton Beam Radiation Therapy for Central Nervous System (CNS) Germ Cell Tumors [NA]
This clinical trial update concerns proton beam radiation therapy for central nervous system germ cell tumors. Sponsored by Massachusetts Ge…
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CLINICAL_TRIALS trial_result · 2026-02-06Clinical Trial Update: A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas [Phase 1]
Phase 1 study evaluating CD45RA+ depleted haploidentical stem cell transplantation in children with relapsed or refractory solid tumors and …
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Germ Cell Tumor and Testicular Tumor DNA Registry
This entry describes a Germ Cell Tumor and Testicular Tumor DNA Registry clinical trial, currently recruiting at Memorial Sloan Kettering Ca…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: A Single-arm, Phase II Clinical Trial of ASPIRin to prEvent Venous Thromboembolism in Patients With Advanced Germ Cell Tumors Receiving Chemotherapy [Phase 2]
A single-arm Phase II trial evaluating aspirin for prevention of venous thromboembolism in patients with advanced germ cell tumors receiving…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Evaluating Immune Therapy, Duravalumab (MEDI4736) With Tremelimumab for Relapsed/Refractory Germ Cell Tumors [Phase 2]
Phase 2 clinical trial evaluating the combination of durvalumab and tremelimumab for relapsed/refractory germ cell tumors; the study is curr…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors [Phase 2]
Status update on a Phase 2 trial of nivolumab plus ipilimumab for advanced rare genitourinary tumors; the study is currently active but not …
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: A Phase II Trial of Cabozantinib With Patients With Refractory GCTs [Phase 2]
Update on a Phase II trial of cabozantinib in patients with refractory germ cell tumors.
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: CD30 CAR for CD30+ NSGCT [Phase 2]
Phase 2 clinical trial evaluating CD30-targeted CAR-T cell therapy for CD30-positive nonseminomatous germ cell tumors has completed.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors [Phase 1]
Phase 1 trial evaluating locoregional HER2-targeted CAR T-cell therapy for pediatric recurrent or refractory central nervous system tumors a…
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors [Phase 1]
Phase 1 trial evaluating locoregional EGFR806-specific CAR T cells for EGFR-positive pediatric CNS tumors. The study status is completed.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification
This clinical trial update describes an observational study by the EORTC to assess treatment patterns and outcomes for patients with primary…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Maintenance Zanzalintinib With Etoposide After HDCT in GCT [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating maintenance zanzalintinib with etoposide after high-dose chemotherapy in germ cell tumors; currently r…
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: Molecular Epidemiology of Pediatric Germ Cell Tumors
A pediatric clinical trial by the Children's Oncology Group to study the molecular epidemiology of germ cell tumors and their histologic sub…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Treatment of Newly Diagnosed Central Malignant Germ Cell Tumor People With Teniposide Injection Combined With Cisplatin. [Phase 2]
Phase 2 trial update evaluating teniposide with cisplatin for newly diagnosed Central Malignant Germ Cell Tumor, with recruitment ongoing.
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Clinical Study of Chemotherapy in the Treatment of Recurrent/Refractory Yolk Sac Tumor in Children [Phase 2, Phase 3]
A pediatric trial evaluating chemotherapy for recurrent or refractory yolk sac tumor has completed Phase 2 and Phase 3 studies.