Clinical Trial Update: Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors [Phase 1, Phase 2]

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Summary

Phase 1/2 clinical trial evaluating melphalan, carboplatin, mannitol, and sodium thiosulfate for recurrent or progressive central nervous system embryonal and g…

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Diseases / indications

• Central Nervous System Embryonal Neoplasm
• Childhood Central Nervous System Embryonal Neoplasm
• Embryonal Tumor with Multilayered Rosettes C19mc-altered
• Germ Cell Tumor
• Malignant Germ Cell Tumor
• Medulloblastoma
• Medulloepithelioma
• Primitive Neuroectodermal Tumor

Drugs mentioned

• CARBOPLATIN (Carboplatin)
• Mannitol (mannitol)
• Melphalan (Melphalan)
• Sodium thiosulfate (sodium thiosulfate)

Snippet

Sponsor: OHSU Knight Cancer Institute | Conditions: Central Nervous System Embryonal Neoplasm, Embryonal Tumor With Multilayered Rosettes, C19MC-Altered | Phase 1, Phase 2 | Status: UNKNOWN