Germ Cell Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Thalidomide Combined With Chemotherapy in the Treatment of Relapsed or Refractory Yolk Sac Tumor [Phase 2]
Phase 2 trial evaluating thalidomide combined with chemotherapy for relapsed or refractory yolk sac tumor and other germ cell tumors has bee…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Dornase Alfa and Cisplatin in Refractory Germ Cell Cancer. [Phase 2]
A Phase 2 clinical trial evaluating the combination of Dornase alfa and cisplatin for refractory germ cell tumors is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Role of Axumin PET Scan in Germ Cell Tumor
This clinical trial evaluated the role of Axumin PET imaging in germ cell tumors, including testicular cancer. The study status is completed…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: High-dose Chemotherapy as Second-line Drug Therapy for Relapsed Germ Cell Tumors [Phase 2]
Phase 2 clinical trial evaluating high-dose chemotherapy as second-line therapy for relapsed germ cell tumors; the study is currently recrui…
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Research of Double-positive Circulating Cells (Tumor Marker / CD45+) in Several Types of Metastatic Cancers [NA]
A multi-cancer prospective study evaluating double-positive circulating cells (CD45+ tumor marker) in several types of metastatic cancers; r…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling [Phase 1]
Phase 1 clinical trial evaluating ex vivo drug sensitivity testing and multi-omics profiling in pediatric cancers. Recruitment is ongoing ac…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: Symptom Management for YA Cancer Survivors [NA]
A completed clinical trial (NCT04035447) examining symptom management for young adult cancer survivors with results posted in 2025.
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours [Phase 3]
A Phase 3 trial comparing accelerated versus standard BEP chemotherapy for intermediate- and poor-risk metastatic germ cell tumors is curren…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Thromboprophylaxis in Good and Intermediate Prognosis Advanced Germ Cell Tumors [Phase 3]
Ongoing Phase 3 study evaluating thromboprophylaxis in good and intermediate prognosis advanced germ cell tumors is currently recruiting.
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CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCT [Phase 2]
A Phase 2 trial is evaluating maintenance oral etoposide after high-dose chemotherapy for germ cell tumors. The study compares maintenance t…
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CLINICAL_TRIALS trial_result · 2025-01-30Clinical Trial Update: Olaparib as Salvage Treatment for Cisplatin-resistant Germ Cell Tumor [Phase 2]
A Phase 2 clinical trial evaluating olaparib as salvage therapy for cisplatin-resistant germ cell tumors has completed, assessing safety and…
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients with Relapsed or Refractory Germ Cell Tumors [Phase 3]
This entry describes a Phase 3 trial comparing standard-dose versus high-dose combination chemotherapy with stem cell transplant for relapse…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors [Phase 1]
Phase 1 trial completion evaluating MR-guided High Intensity Focused Ultrasound (HIFU) for relapsed or refractory pediatric solid tumors, in…
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CLINICAL_TRIALS withdrawal · 2025-01-01Clinical Trial Update: A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors [Phase 2]
A Phase 2 pilot study evaluating Thermodox in combination with MR-HIFU for relapsed solid tumors has been withdrawn.
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: Morbidity, Long-term Side Effects and Quality of Life in Germ-cell Tumor Long Survivors Treated with High-dose Chemotherapy and Autologous Stem Cell Transplant [NA]
This is a clinical trial registration describing a study focused on morbidity, long-term side effects, and quality of life in germ-cell tumo…
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Pembrolizumab in Treating Patients With Rare Tumors That Cannot Be Removed by Surgery or Are Metastatic [Phase 2]
Phase 2 study of pembrolizumab in patients with rare, unresectable or metastatic solid tumors; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-06-14Clinical Trial Update: A Novel Single Arm Phase II Study for Relapsed Germ Cell Tumours With Poor Prognosis [Phase 2]
Single-arm Phase II trial evaluating a novel therapy for relapsed germ cell tumors with poor prognosis has completed.
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CLINICAL_TRIALS research · 2024-05-20Clinical Trial Update: Establishing Prospective Mediastinal Tumor Database of PUMCH
A prospective Mediastinal Tumor Database is being established at Peking Union Medical College Hospital, enrolling cases of thymic epithelial…
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CLINICAL_TRIALS trial_result · 2024-04-09Clinical Trial Update: A Pilot RCT of the PRISM Intervention for AYAs With Cancer [Phase 2]
pilot randomized Phase 2 trial evaluating the PRISM intervention for adolescents and young adults with cancer, completed.
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CLINICAL_TRIALS trial_result · 2023-10-04Clinical Trial Update: Disulfiram and Cisplatin in Refractory TGCTs. [Phase 2]
Phase 2 clinical trial evaluating disulfiram in combination with cisplatin for refractory germ cell tumors has completed.
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CLINICAL_TRIALS trial_result · 2023-07-13Clinical Trial Update: Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors [Phase 2]
A Phase 2 clinical trial evaluated memantine for preventing cognitive late effects in pediatric patients undergoing cranial radiation therap…
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CLINICAL_TRIALS trial_result · 2021-11-10Clinical Trial Update: A Study to Assess the Safety and Efficacy of ASP1650, a Monoclonal Antibody Targeting Claudin 6 (CLDN6), in Male Subjects With Incurable Platinum Refractory Germ Cell Tumors [Phase 2]
Phase 2 study evaluating ASP1650, a monoclonal antibody targeting Claudin 6, in men with incurable platinum-refractory germ cell tumors has …
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CLINICAL_TRIALS trial_result · 2021-10-26Clinical Trial Update: Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating melphalan, carboplatin, mannitol, and sodium thiosulfate for recurrent or progressive central nervous sy…
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CLINICAL_TRIALS trial_result · 2021-06-07Clinical Trial Update: Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors [Phase 3]
Phase 3 trial evaluating combination chemotherapy for stage II or stage III germ cell tumors has completed enrollment and posted results. Th…
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CLINICAL_TRIALS trial_result · 2020-12-10Clinical Trial Update: Study of Brentuximab Vedotin And Bevacizumab In Refractory CD-30 Positive Germ Cell Tumors [Phase 2]
Phase 2 study investigating brentuximab vedotin with bevacizumab in refractory CD-30 positive germ cell tumors was terminated; results poste…