Gastrointestinal Stromal Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-07-10Clinical Trial Update: Neoadjuvant and Adjuvant Imatinib Mesylate in Treating Patients With Primary or Recurrent Malignant Gastrointestinal Stromal Tumor [Phase 2]
Phase 2 trial evaluating neoadjuvant and adjuvant imatinib mesylate for primary or recurrent malignant gastrointestinal stromal tumor (GIST)…
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CLINICAL_TRIALS trial_result · 2013-06-19Clinical Trial Update: Non-Interventional Retrospective Correlation Of Tumor Mutational Status To Clinical Benefit Of GIST Patients Treated With Sunitinib
A completed non-interventional retrospective study evaluated the relationship between tumor mutational status and clinical benefit in Gastro…
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CLINICAL_TRIALS trial_result · 2013-06-07Clinical Trial Update: A Phase 2 Study of XL820 in Adults With Advanced GIST Resistant to Imatinib and/or Sunitinib [Phase 2]
This document reports the completion of a Phase 2 study evaluating XL-820 in adults with advanced gastrointestinal stromal tumors resistant …
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CLINICAL_TRIALS trial_result · 2013-06-05Clinical Trial Update: Oblimersen and Imatinib Mesylate in Treating Patients With Advanced Gastrointestinal Stromal Tumors That Cannot Be Removed By Surgery [Phase 2]
This Phase 2 trial evaluated oblimersen in combination with imatinib mesylate for advanced, unresectable gastrointestinal stromal tumors and…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: CCI-779 in Treating Patients With Soft Tissue Sarcoma or Gastrointestinal Stromal Tumor [Phase 2]
Phase 2 trial of temsirolimus (CCI-779) in soft tissue sarcoma and gastrointestinal stromal tumor has completed.
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CLINICAL_TRIALS trial_result · 2013-05-23Clinical Trial Update: The Effect of Food (High Fat and Low Fat Breakfast) on the Pharmacokinetics of Regorafenib [Phase 1]
This Phase 1 study assessed how a high-fat versus low-fat breakfast affects regorafenib pharmacokinetics; the trial has completed.
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CLINICAL_TRIALS trial_result · 2013-05-13Clinical Trial Update: Patients Completing Core Protocol (CAMN107A2103), Exhibiting Stable Disease (SD), Partial Response (PR) or Complete Response (CR) to Nilotinib in Combination With Imatinib [Phase 1]
Phase 1 study CAMN107A2103 in gastrointestinal stromal tumors shows patients achieving stable disease, partial response, or complete respons…
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CLINICAL_TRIALS trial_result · 2013-04-29Clinical Trial Update: Study of AMG 706 in Subjects With Advanced Gastrointestinal Stromal Tumors (GISTs) [Phase 2]
This document reports the completion of a Phase 2 study evaluating AMG 706 in subjects with advanced gastrointestinal stromal tumors (GIST).…
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CLINICAL_TRIALS trial_result · 2013-03-19Clinical Trial Update: Doxorubicin Hydrochloride and Alvocidib in Treating Patients With Metastatic or Recurrent Sarcoma That Cannot Be Removed By Surgery [Phase 1]
Phase 1 trial evaluating the combination of doxorubicin hydrochloride and alvocidib in patients with metastatic or recurrent soft tissue sar…
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CLINICAL_TRIALS trial_result · 2013-02-20Clinical Trial Update: Imatinib Mesylate in Treating Patients With Gastrointestinal Stromal Tumor That Has Been Completely Removed During Surgery [Phase 2]
Phase 2 trial evaluating imatinib mesylate as adjuvant therapy after complete surgical resection of gastrointestinal stromal tumor; study co…
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CLINICAL_TRIALS trial_result · 2013-02-11Clinical Trial Update: SU5416 in Treating Patients With Advanced, Metastatic, or Recurrent Soft Tissue Sarcomas [Phase 2]
A Phase 2 study of SU5416 in patients with advanced, metastatic, or recurrent soft tissue sarcomas, including gastrointestinal stromal tumor…
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CLINICAL_TRIALS trial_result · 2013-02-07Clinical Trial Update: Imatinib Mesylate in Treating Patients With Advanced Cancer and Liver Dysfunction [Phase 1]
This clinical trial update summarizes a Phase 1 study of Imatinib Mesylate in patients with advanced cancer and liver dysfunction, which has…
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FDA approval · 2013-01-25FDA Approved: GLEEVEC — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for GLEEVEC (imatinib mesylate) submitted by Novartis, reflecting changes to the product labeling.
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: EUS-guided Fine Needle Biopsy With a New Core Histology Needle Versus Conventional Fine Needle Aspiration [NA]
A completed clinical trial comparing a new core histology needle used for EUS-guided fine-needle biopsy with conventional fine-needle aspira…
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CLINICAL_TRIALS research · 2013-01-15Clinical Trial Update: ESTD vs. VATS for Upper Gastrointestinal Submucosal Tumors [NA]
Update on a trial comparing endoscopic submucosal tunnel dissection (ESTD) with video-assisted thoracoscopic surgery (VATS) for upper gastro…
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CLINICAL_TRIALS trial_result · 2013-01-03Clinical Trial Update: S9926 Temozolomide in Patients With Unresectable/Metastatic Gastrointestinal Stromal Tumors [Phase 2]
Phase 2 trial update of temozolomide in patients with unresectable or metastatic gastrointestinal stromal tumors (S9926) has completed.
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CLINICAL_TRIALS trial_result · 2012-11-21Clinical Trial Update: Study of Imatinib and Peginterferon α-2b in Gastrointestinal Stromal Tumor (GIST) Patients [Phase 2]
Phase 2 study evaluating imatinib in combination with peginterferon alfa-2b in patients with gastrointestinal stromal tumors. The trial was …
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CLINICAL_TRIALS trial_result · 2012-09-24Clinical Trial Update: STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma [Phase 1, Phase 2]
Phase 1/2 trial update of STI571 (imatinib) in patients with recurrent or refractory soft tissue sarcoma; the study status is reported as co…
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CLINICAL_TRIALS trial_result · 2012-09-24Clinical Trial Update: Imatinib Mesylate With or Without Surgery in Treating Patients With Metastatic Gastrointestinal Stromal Tumor That is Responding to Imatinib Mesylate [Phase 3]
Phase 3 trial evaluating imatinib mesylate with or without surgery for metastatic gastrointestinal stromal tumor that responds to imatinib h…
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CLINICAL_TRIALS withdrawal · 2012-08-02Clinical Trial Update: Tasigna Neoadjuvant Gastrointestinal Stromal Tumor (GIST) [Phase 2]
A Phase 2 neoadjuvant trial of Tasigna (nilotinib) for gastrointestinal stromal tumor has been withdrawn.
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CLINICAL_TRIALS trial_result · 2012-08-02Clinical Trial Update: Gastrointestinal Stromal Tumors (GIST) Registry
Clinical trial update for the Gastrointestinal stromal tumor (GIST) Registry sponsored by MD Anderson Cancer Center shows the study status a…
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CLINICAL_TRIALS trial_result · 2012-07-18Clinical Trial Update: Brostallicin in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma [Phase 2]
A Phase 2 study evaluating brostallicin in patients with locally advanced or metastatic soft tissue sarcoma has completed.
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CLINICAL_TRIALS trial_result · 2012-07-16Clinical Trial Update: The Biological Activity of Cediranib (AZD2171) in Gastro-Intestinal Stromal Tumours(GIST). [Phase 2]
Phase 2 study evaluating the biological activity of cediranib (AZD2171) in gastrointestinal stromal tumors and related soft tissue sarcomas;…
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CLINICAL_TRIALS trial_result · 2012-06-06Clinical Trial Update: Endoscopic Placement of Metal Stent in Patients With Cancer-Related Bowel Obstruction [Phase 1, Phase 2]
This entry reports completion of a Phase 1/2 trial evaluating endoscopic placement of a metal stent to treat cancer-related bowel obstructio…
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CLINICAL_TRIALS trial_result · 2012-06-06Clinical Trial Update: Octreotide as Palliative Therapy for Cancer-Related Bowel Obstruction That Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial evaluating octreotide as palliation for cancer-related bowel obstruction that cannot be removed by surgery; the study has comp…