Gastrointestinal Stromal Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2015-02-02Clinical Trial Update: Prospective Cohort Study of the Clinical Applications for the Pathologic Type, Staging, and Grading of GIST
A clinical trial update describing a prospective cohort study investigating how pathologic type, staging, and grading are applied to gastroi…
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Comparison of Two Different Doses of STI571 in Treating Patients With Metastatic or Unresectable Gastrointestinal Stromal Tumor [Phase 3]
Phase 3 trial comparing two doses of STI571 (imatinib) for metastatic or unresectable gastrointestinal stromal tumor was terminated; the upd…
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FDA approval · 2014-12-19FDA Approved: SUTENT — Supplemental Application (U.S. Pharmaceuticals)
The FDA approved a supplemental application for Sutent (sunitinib malate) submitted by U.S. Pharmaceuticals.
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CLINICAL_TRIALS trial_result · 2014-10-07Clinical Trial Update: Radiation Therapy as Palliative Treatment of GIST [Phase 1, Phase 2]
Clinical trial update on using radiation therapy as palliative treatment for gastrointestinal stromal tumor (GIST). The study is a Phase 1/P…
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CLINICAL_TRIALS trial_result · 2014-10-01Clinical Trial Update: A Clinical Trial to Compare the Pharmacokinetics of Imatinib Mesylate Tablet 400mg (1 Tablet) and Glivec Film-coated Tablet 100mg (4 Tablets)(Phase I) [Phase 1]
A Phase I pharmacokinetic study comparing Imatinib Mesylate 400 mg (1 tablet) with Glivec 100 mg film-coated tablet (4 tablets) to assess PK…
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FDA approval · 2014-09-25FDA Approved: TASIGNA — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for Tasigna (nilotinib) submitted by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS research · 2014-09-22Clinical Trial Update: A Clinical Trial With a New Needle Device Comparing Two Needles for EUS_FNA of Solid Lesions. [NA]
A clinical trial update describes a study comparing two needle devices for endoscopic ultrasound-guided fine-needle aspiration of solid lesi…
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CLINICAL_TRIALS trial_result · 2014-07-15Clinical Trial Update: A Study of the Efficacy and Safety of Imatinib Mesylate in Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing C-kit Gene [Phase 2]
Phase 2 trial results evaluate the efficacy and safety of imatinib mesylate in patients with unresectable or metastatic gastrointestinal str…
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CLINICAL_TRIALS trial_result · 2014-07-04Clinical Trial Update: Imatinib Mesylate in Treating Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumor [Phase 3]
A Phase 3 clinical trial is evaluating Imatinib Mesylate for unresectable or metastatic gastrointestinal stromal tumor; the trial status is …
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CLINICAL_TRIALS trial_result · 2014-06-27Clinical Trial Update: Comparative Bioequivalence Study in Adult Patients Suffering From Chronic Myeloid Leukemia & Gastrointestinal Stromal Tumor Under Fed Conditions [Phase 2, Phase 3]
This update reports the completion of a Phase 2/3 comparative bioequivalence study in adults with chronic myeloid leukemia and gastrointesti…
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CLINICAL_TRIALS trial_result · 2014-04-21Clinical Trial Update: Dose-Escalation Study of TH-302 in Combination With Sunitinib to Treat Patients With Advanced Renal Cell Carcinoma,Gastrointestinal Stromal Tumors and Pancreatic Neuroendocrine Tumors [Phase 1]
Phase 1 dose-escalation study of TH-302 in combination with sunitinib for advanced renal cell carcinoma, gastrointestinal stromal tumors, an…
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CLINICAL_TRIALS trial_result · 2014-03-14Clinical Trial Update: The Effects of Preoperative and Postoperative Oral Nutritional Supplements in Malnourished Post-gastrectomy Patients [NA]
A completed clinical trial evaluating the effects of preoperative and postoperative oral nutritional supplements in malnourished patients af…
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CLINICAL_TRIALS trial_result · 2014-02-27Clinical Trial Update: Evaluate the Efficacy of AMG 706 to Treat Advanced Gastrointestinal Stromal Tumors [Phase 2]
Phase 2 trial evaluating AMG 706 (motesanib) for advanced gastrointestinal stromal tumors has completed.
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CLINICAL_TRIALS trial_result · 2014-02-24Clinical Trial Update: Regorafenib in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor [Phase 2]
Phase 2 trial update for regorafenib in patients with metastatic or unresectable gastrointestinal stromal tumor (GIST) completed with posted…
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CLINICAL_TRIALS trial_result · 2014-02-24Clinical Trial Update: Prospective Multicentric Randomized Study of Glivec® in Advanced GIST Expressing C-kit: Interruption After 5 Years vs Maintenance [Phase 3]
A Phase 3 multicenter randomized study of imatinib (Glivec) in advanced gastrointestinal stromal tumors expressing C-kit was interrupted aft…
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CLINICAL_TRIALS trial_result · 2014-02-19Clinical Trial Update: Perifosine + Sunitinib Malate for Patients With Advanced Cancers [Phase 1]
Phase 1 study evaluating perifosine in combination with sunitinib malate for patients with advanced cancers has completed.
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CLINICAL_TRIALS research · 2014-01-22Clinical Trial Update: A Retrospective Study of C-kit Mutation Status in Asian Patients With Advanced Gastro-intestinal Stromal Tumors (GIST) Treated With Imatinib.
This clinical trial update reports a retrospective analysis of C-kit mutation status in Asian patients with advanced gastrointestinal stroma…
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CLINICAL_TRIALS trial_result · 2014-01-21Clinical Trial Update: Sorafenib in Treating Patients With Malignant Gastrointestinal Stromal Tumor That Progressed During or After Previous Treatment With Imatinib Mesylate and Sunitinib Malate [Phase 2]
This entry reports results from a Phase 2 trial evaluating sorafenib in patients with malignant gastrointestinal stromal tumor that progress…
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CLINICAL_TRIALS trial_result · 2013-12-04Clinical Trial Update: Nitrocamptothecin in Treating Patients With Soft Tissue Sarcomas [Phase 2]
This is a completed Phase 2 trial of Nitrocamptothecin in patients with soft tissue sarcomas, including gastrointestinal stromal tumors and …
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EMA withdrawal · 2013-11-22EMA Refused: Masican (masitinib) — AB Science
EMA refused Masican (masitinib) for gastrointestinal stromal tumors; the marketing authorization application was rejected.
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CLINICAL_TRIALS trial_result · 2013-10-30Clinical Trial Update: Phase II Trial of Locally Advanced/Metastatic Soft Tissue Sarcoma or Advanced/Metastatic Malignant GIST [Phase 2]
Completed Phase II trial evaluating therapy for locally advanced or metastatic soft tissue sarcoma and advanced/metastatic malignant gastroi…
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CLINICAL_TRIALS trial_result · 2013-10-24Clinical Trial Update: Effect of Imatinib on Bone Metabolism in Patients With Chronic Myelogenous Leukemia or Gastrointestinal Stromal Tumors [NA]
A completed clinical trial evaluating how imatinib affects bone metabolism in patients with chronic myelogenous leukemia or gastrointestinal…
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FDA approval · 2013-09-13FDA Approved: STIVARGA — Supplemental Application (Bayer HealthCare Pharmaceuticals Inc.)
FDA approved a supplemental application for Stivarga (regorafenib) submitted by Bayer HealthCare Pharmaceuticals Inc.
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FDA approval · 2013-08-30FDA Approved: SUTENT — Supplemental Application (U.S. Pharmaceuticals)
The FDA overview notes a supplemental application for Sutent (sunitinib malate) submitted by U.S. Pharmaceuticals. The submission status is …
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CLINICAL_TRIALS trial_result · 2013-07-16Clinical Trial Update: Imatinib Mesylate in Treating Patients With Primary Gastrointestinal Stromal Tumor That Has Been Completely Removed By Surgery [Phase 3]
Phase 3 trial evaluating imatinib mesylate as adjuvant therapy for patients with primary gastrointestinal stromal tumor completely removed b…