Gastrointestinal Stromal Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: PH 2 Pemigatinib in SDH-deficient GIST [Phase 2]
Phase 2 study of pemigatinib in SDH-deficient gastrointestinal stromal tumor is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Dose Finding Study of TNO155 in Adult Patients With Advanced Solid Tumors [Phase 1]
Novartis' Phase 1 dose-finding trial of TNO155 in adults with advanced solid tumors has been terminated. No efficacy results are provided in…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Paclitaxel in Patients With GIST With Low P-glycoprotein Expression After Failure of at Least Imatinib and Sunitinib, and Regorafenib. [Phase 2]
A Phase 2 trial evaluating paclitaxel in gastrointestinal stromal tumor patients with low P-glycoprotein expression after failure of imatini…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy [Phase 3]
A Phase 3 randomized trial evaluating IDRX-42 (GSK6042981) versus sunitinib in patients with gastrointestinal stromal tumors after imatinib …
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Safety and Efficacy of Avapritinib in Chinese Patients With Gastrointestinal Stromal Tumor (GIST) in the Real World
A real-world clinical trial update reports on the safety and efficacy of avapritinib in Chinese patients with gastrointestinal stromal tumor…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: Treatment of Patients With Metastatic or Unresectable Gastrointestinal Stromal Tumors in First Line With Nilotinib [Phase 4]
Phase 4 trial results update on using nilotinib as first-line therapy for metastatic or unresectable gastrointestinal stromal tumors (GIST);…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Patterns of Care and Outcomes of Patients With METAstatic Gastrointestinal Stromal Tumors (METAGIST)
A completed clinical trial assessing patterns of care and outcomes in patients with metastatic gastrointestinal stromal tumors (METAGIST).
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Ripretinib (QINLOCK®) According to Current SmPC
Ripretinib for Gastrointestinal stromal tumor has a completed trial (NCT06619275). The update indicates that the trial findings are consiste…
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CLINICAL_TRIALS trial_result · 2025-10-31Clinical Trial Update: SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST [Phase 2]
Update on the SARC044 Phase II trial evaluating the combination of bezuclastinib and sunitinib in patients with gastrointestinal stromal tum…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Phase Ib Study of TNO155 in Combination With Spartalizumab or Ribociclib in Selected Malignancies [Phase 1]
Phase Ib study of TNO155 in combination with Spartalizumab or Ribociclib in selected malignancies was terminated, involving multiple indicat…
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CLINICAL_TRIALS trial_result · 2025-05-20Clinical Trial Update: An Observational Study to Learn More About Treatment With Regorafenib in People With Advanced Gastrointestinal Stromal Tumors in the United States
This clinical trial update reports on an observational study evaluating the use of regorafenib in patients with advanced gastrointestinal st…
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CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: Comparison of Tumor Efficacy Safety in Laparoscopic Resection of Gastrointestinal Stromal Tumors Between Favorable and Unfavorable Site
Clinical trial update on a study comparing tumor efficacy and safety of laparoscopic resection for gastrointestinal stromal tumors of the st…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Preventing Viral Pandemic Associated Risk of Cancer Death Using Less Invasive Diagnostic Tests- Liquid Biopsies
Completed clinical trial update evaluating the use of liquid biopsies to reduce cancer death risk during viral pandemics. The provided snipp…
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CLINICAL_TRIALS trial_result · 2025-02-26Clinical Trial Update: Comparison of Clinical Efficacy of Liver Resection, RFA, TACE, and Drug Therapy in Patients with GIST LM
Completed clinical trial comparing liver resection, radiofrequency ablation, transarterial chemoembolization, and drug therapy in patients w…
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: A Study to Assess DCC-2618 and Sunitinib in Patients With Advanced GIST After Treatment With Imatinib [Phase 2]
Phase 2 trial evaluating DCC-2618 in combination with Sunitinib in patients with advanced gastrointestinal stromal tumor after imatinib fail…
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CLINICAL_TRIALS trial_result · 2025-01-01Clinical Trial Update: The GALLOP-11 Study
The GALLOP-11 trial (NCT05178030) conducted by University Medical Center Groningen for gastrointestinal stromal tumors has completed.
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: A Drug-drug Interaction Study of Avapritinib and Midazolam [Phase 1]
Phase 1 drug-drug interaction study of avapritinib with midazolam has completed. The snippet does not provide study results.
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CLINICAL_TRIALS trial_result · 2024-11-26Clinical Trial Update: Study for Patients Previously Treated in Avapritinib Clinical Trials [Phase 4]
Phase 4 clinical trial update for patients previously treated with avapritinib in gastrointestinal stromal tumors has completed and results …
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: Correlation Between Imatinib Trough Concentration and Efficacy in Advanced GIST Patients with Different Genotypes
A clinical trial update examining the relationship between imatinib trough concentrations and efficacy in advanced gastrointestinal stromal …
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: Registry For Temsirolimus, Sunitinib, And Axitinib Treated Patients With Metastatic Renal Cell Carcinoma (mRCC), Mantle Cell Lymphoma (MCL), And Gastro-Intestinal Stroma Tumor (GIST) [STAR-TOR]
Pfizer-sponsored STAR-TOR registry study update reports completion and posted results for a three-drug regimen of temsirolimus, sunitinib, a…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Drug-Drug Interaction Study to Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Probe Substrate in Patients with Advanced GIST [Phase 1]
Phase 1 trial update describing a drug-drug interaction study to assess how ripretinib affects the pharmacokinetics of a CYP2C8 probe substr…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: A Study to Investigate the Safety and Efficacy of AT13387, Alone or in Combination With Imatinib, in Patients With GIST [Phase 2]
Phase 2 trial evaluating AT13387 alone or with imatinib in gastrointestinal stromal tumor (GIST) has completed safety and efficacy assessmen…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: GIST and Memory and Attention Adaptation Training [NA]
Clinical trial investigating Memory and Attention Adaptation Training for malignant gastrointestinal stromal tumors was terminated.
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Advanced Gastrointestinal Endoscopic Imaging [NA]
A clinical trial update on Advanced Gastrointestinal Endoscopic Imaging shows the study was terminated and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Multicentre Placebo-controlled Double-blinded Phase II Study of Lenvatinib Efficacy in Patients With Locally Advanced or Metastatic GIST (Gastrointestinal Stromal Tumor) After Imatinib/Sunitinib Failure [Phase 2]
This is a multicentre, placebo-controlled, double-blind Phase II trial evaluating lenvatinib in patients with locally advanced or metastatic…