Gastrointestinal Stromal Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-06-06Clinical Trial Update: Endoscopic Placement of Metal Stents in Treating Patients With Cancer- Related Duodenal Obstruction [Phase 1, Phase 2]
This multi-phase trial evaluated endoscopic placement of metal stents to treat cancer-related duodenal obstruction in patients with several …
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CLINICAL_TRIALS withdrawal · 2012-05-28Clinical Trial Update: Collection of Biospecimen & Clinical Information in Patients w/ Gastrointestinal Cancers
A clinical trial on collection of biospecimens and clinical information from patients with gastrointestinal and gynecologic cancers was with…
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CLINICAL_TRIALS approval · 2012-03-09Clinical Trial Update: A Treatment Protocol for Patients With Gastrointestinal Stromal Tumor (GIST) Who May Derive Benefit From Treatment With SU011248
Pfizer's SU011248 (sunitinib) for gastrointestinal stromal tumor has been approved for marketing.
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CLINICAL_TRIALS trial_result · 2012-03-08Clinical Trial Update: Imatinib Mesylate in Treating Patients With Locally Advanced Gastrointestinal Stromal Tumor [Phase 2]
Phase 2 trial of imatinib mesylate in locally advanced gastrointestinal stromal tumor has completed. Trial results are not detailed in the p…
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CLINICAL_TRIALS trial_result · 2012-01-06Clinical Trial Update: Study on the Evolution of Genes Mutation Related With Gastrointestinal Stromal Tumors
A completed clinical trial from Guangxi Medical University analyzes full gene sequences of c-KIT, PDGFRA, and DOG1 to characterize mutations…
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CLINICAL_TRIALS trial_result · 2011-12-30Clinical Trial Update: Study Comparing 12 Months Versus 36 Months of Imatinib in the Treatment of Gastrointestinal Stromal Tumor (GIST) [Phase 3]
A Phase 3 study compares 12 months versus 36 months of imatinib therapy in patients with gastrointestinal stromal tumor (GIST) to determine …
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CLINICAL_TRIALS trial_result · 2011-11-16Clinical Trial Update: Imatinib Mesylate and Sunitinib in Treating Patients With Gastrointestinal Stromal Tumors [Phase 1]
Phase 1 trial evaluating imatinib mesylate and sunitinib for gastrointestinal stromal tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2011-11-02Clinical Trial Update: Evaluation of Cognitive Function of Patients With Sunitinib or Sorafenib
The document reports a completed clinical trial evaluating cognitive function in patients treated with sunitinib or sorafenib for metastatic…
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CLINICAL_TRIALS trial_result · 2011-09-16Clinical Trial Update: Study to the Optimal Duration of Therapy With Oral Angiogenesis Inhibitors [Phase 4]
This Phase 4 clinical trial update discusses evaluating the optimal duration of therapy with oral angiogenesis inhibitors in patients with r…
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CLINICAL_TRIALS trial_result · 2011-08-08Clinical Trial Update: Preoperative and Postoperative Imatinib Mesylate Study in Patients With c-Kit Positive GIST [Phase 2]
Phase 2 study of preoperative and postoperative imatinib mesylate for c-KIT positive gastrointestinal stromal tumors has completed.
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CLINICAL_TRIALS trial_result · 2011-07-01Clinical Trial Update: A Prospective, Multicenter Study on Best Clinical Use of Imatinib in the Advanced Gastrointestinal Stromal Tumors [Phase 2]
A prospective, multicenter Phase 2 study evaluates the best clinical use of imatinib in advanced gastrointestinal stromal tumors. The trial …
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CLINICAL_TRIALS trial_result · 2011-04-06Clinical Trial Update: Combination Chemotherapy in Treating Patients With Stage III Ovarian Epithelial Cancer or Gastrointestinal Cancer [Phase 2]
Phase 2 trial evaluating combination chemotherapy in patients with Stage III ovarian epithelial cancer or various gastrointestinal cancers. …
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CLINICAL_TRIALS trial_result · 2011-03-29Clinical Trial Update: Impact of the Inhibitors of Tyrosine Kinase on the Male Fertility [NA]
This clinical trial update assesses how tyrosine kinase inhibitors affect male fertility in patients with chronic myeloid leukemia or gastro…
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CLINICAL_TRIALS trial_result · 2010-12-31Clinical Trial Update: Safety And Effectiveness Of Daily Dosing With Sunitinib Or Imatinib In Patients With Gastrointestinal Stromal Tumors [Phase 3]
Phase 3 trial comparing daily sunitinib versus imatinib in patients with gastrointestinal stromal tumors has been terminated with results po…
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CLINICAL_TRIALS trial_result · 2010-12-28Clinical Trial Update: Vaccine Therapy and Sargramostim in Treating Patients With Sarcoma or Brain Tumor [Phase 1]
A Phase 1 trial evaluated a vaccine therapy in combination with sargramostim for patients with sarcoma or brain/central nervous system tumor…
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CLINICAL_TRIALS trial_result · 2010-05-27Clinical Trial Update: PTK787/ZK222584 in the Treatment of Metastatic Gastrointestinal Stromal Tumors Resistant to Imatinib [Phase 2]
The document describes the completion of a Phase 2 clinical trial of PTK787/ZK222584 for metastatic gastrointestinal stromal tumors resistan…
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CLINICAL_TRIALS trial_result · 2010-03-18Clinical Trial Update: Study of the Immunoresponse in Patients Treated With a Tyrosine Kinase Inhibitor
A completed clinical trial update investigating immunoresponse in patients treated with a tyrosine kinase inhibitor for renal cell carcinoma…
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CLINICAL_TRIALS trial_result · 2010-03-10Clinical Trial Update: Follow-up of the Natural Course of the Small EUS-suspected Gastric Gastointestinal Stromal Tumors
Clinical trial NCT01084460, sponsored by National Taiwan University Hospital, completed follow-up to observe the natural course of small EUS…
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CLINICAL_TRIALS trial_result · 2009-11-13Clinical Trial Update: A Phase I/II Study of Sunitinib Malate (SU011248) In Patients With Gastrointestinal Stromal Tumor (GIST) [Phase 1, Phase 2]
Phase I/II study of sunitinib malate (SU011248) in patients with gastrointestinal stromal tumors has completed with results posted in 2009.
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CLINICAL_TRIALS trial_result · 2009-10-21Clinical Trial Update: Current Management of Gastrointestinal Stromal Tumors (GIST) in the Region of Coquimbo
This entry summarizes a completed clinical trial on the current management of gastrointestinal stromal tumors (GIST) in the Coquimbo region,…
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CLINICAL_TRIALS trial_result · 2009-09-28Clinical Trial Update: A Study To Assess The Safety And Efficacy Of SU11248 In Patients With Gastrointestinal Stromal Tumor(GIST) [Phase 3]
Phase 3 clinical trial evaluating the safety and efficacy of SU11248 in patients with gastrointestinal stromal tumor; results were posted in…
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CLINICAL_TRIALS trial_result · 2009-09-04Clinical Trial Update: Study Of SU011248 Administered On A Continuous Daily Dosing Schedule In Patients With Gastrointestinal Stromal Tumor [Phase 2]
A Phase 2 study evaluating continuous daily dosing of SU011248 in patients with gastrointestinal stromal tumors has completed, with results …
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CLINICAL_TRIALS trial_result · 2009-02-13Clinical Trial Update: Chromosome Abnormalities in Chronic Myeloid Leukemia (CML) on Imatinib. GIST Patients on Imatinib [Phase 4]
Phase 4 trial evaluating imatinib for chromosome abnormalities in chronic myeloid leukemia and for gastrointestinal stromal tumors has been …
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FDA approval · 2008-12-19FDA Approved: GLEEVEC — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for GLEEVEC (imatinib mesylate) from Novartis Pharmaceuticals Corporation, resulting in regulatory a…
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CLINICAL_TRIALS trial_result · 2008-06-02Clinical Trial Update: 11C-Acetate PET/CT Non-FDG-Avid Tumors
This clinical trial update discusses the use of 11C-acetate PET/CT for imaging tumors that do not take up FDG. It covers several cancer type…