Gastrointestinal Stromal Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Prospective, Randomized, Multicenter, Comparative Study of the Efficacy of Imatinib Resumption Combined With Atezolizumab Versus Imatinib Resumption Alone in Patients With Unresectable Advanced Gastrointestinal Stromal Tumors (GIST) After Failure of Standard Treatments [Phase 2]
Phase 2 randomized multicenter trial evaluating whether resuming imatinib with atezolizumab improves efficacy versus imatinib alone in unres…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Mesenteric Vascular Preconditioning Combined With Laparoscopic and Endoscopic Cooperative Surgery for Submucosal Tumor at the Gastroesophageal Junction [Phase 2]
Phase 2 clinical trial evaluating mesenteric vascular preconditioning combined with laparoscopic and endoscopic cooperative surgery for subm…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Efficacy and Safety of NB003 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST) [Phase 2, Phase 3]
This clinical trial update covers NB003 for advanced Gastrointestinal Stromal Tumor (GIST) and notes that Phase 2/Phase 3 studies are not ye…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis
A clinical trial update describing a study on surgical approaches for Gastrointestinal Stromal Tumors, including tumor modeling and genomic …
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015) [Phase 2]
This Phase 2 trial update covers belzutifan (MK-6482) for advanced pheochromocytoma/paraganglioma, pancreatic neuroendocrine tumors, von Hip…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Study to Allow Access to Imatinib for Patients Who Are on Imatinib Treatment in a Novartis-sponsored Study and Are Benefiting From the Treatment as Judged by the Investigator [Phase 4]
Phase 4 trial extension allowing access to imatinib for patients currently on imatinib in a Novartis-sponsored study who are judged by inves…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting [Phase 2]
Kumquat Biosciences is conducting a Phase 2 trial evaluating KQB198 in combination with imatinib as first-line therapy for advanced or metas…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial update for Inlexisertib (DCC-3116) in combination with anticancer therapies in participants with advanced maligna…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Anti-cancer Drug, Rogaratinib (BAY 1163877), for Treatment of Advanced Sarcoma With Alteration in Fibroblast Growth Factor Receptor (FGFR 1-4), and in Patients With SDH-deficient Gastrointestinal Stromal Tumor (GIST) [Phase 2]
A Phase 2 clinical trial update on rogaratinib (BAY 1163877) for FGFR1-4-altered advanced sarcoma and SDH-deficient gastrointestinal stromal…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Long-term Survivorship Challenges of Advanced/Metastatic GIST Patients Responding to Tyrosine Kinase Inhibitor Treatment: an Observational Study
This clinical trials entry describes an observational study assessing long-term survivorship challenges in patients with advanced or metasta…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study of HQP1351 in Patients With GIST or Other Solid Tumors [Phase 1]
A Phase 1 clinical trial of HQP1351 in patients with Gastrointestinal stromal tumor and other solid tumors is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Rivoceranib Plus Paclitaxel in Patients With Gastrointestinal Stromal Tumor [Phase 2]
Phase 2 clinical trial evaluating rivoceranib plus paclitaxel in people with Gastrointestinal Stromal Tumor is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: GIST Oral Paclitaxel(Liporaxel) [Phase 2]
An ongoing Phase 2 clinical trial is evaluating oral paclitaxel (Liporaxel) for gastrointestinal stromal tumors, sponsored by Asan Medical C…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Lenvatinib After Progression on Imatinib, Sunitinib, and Regorafenib for GIST Patients [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating lenvatinib in gastrointestinal stromal tumor (GIST) patients after progres…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Neoadjuvant Imatinib and Fampridine in KIT Mutant Gastrointestinal Stromal Tumor [Phase 1]
A Phase 1 neoadjuvant trial evaluating imatinib plus fampridine in KIT-mutant Gastrointestinal Stromal Tumor is currently recruiting at the …
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors [Phase 2]
This is a Phase 2 clinical trial update for avapritinib in KIT or PDGFRA mutation-positive locally advanced or metastatic malignant solid tu…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: RCT of EFTR Versus STER for GIST Treatment [NA]
A randomized trial comparing endoscopic full-thickness resection (EFTR) versus submucosal tunneling endoscopic resection (STER) for small-si…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Safety of Robotic Surgery for GISTs at Special Anatomic Sites [NA]
An update on an ongoing clinical trial evaluating the safety of robotic surgery for gastrointestinal stromal tumors at special anatomical si…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: A Master Protocol to Evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST) [Phase 1, Phase 2]
A master protocol to evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST) across Phase 1 and Phase 2 is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST) [Phase 1]
Kura Oncology is conducting a Phase 1 study of Ziftomenib in combination with Imatinib for advanced gastrointestinal stromal tumors, and the…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: (Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors [Phase 3]
A Phase 3 randomized trial compares CGT9486 plus sunitinib versus sunitinib alone in advanced or metastatic gastrointestinal stromal tumors;…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Phase 2 Study to Evaluate the Efficacy of Regorafenib in Specific GIST Mutation Subsets (KIT Exon 17, 18, or 14 Mutation and SDHB Deficient GIST) in the Post-imatinib Second-line Setting. [Phase 2]
A Phase 2 clinical trial is evaluating regorafenib in selected GIST mutation subtypes after imatinib, in the second-line setting. The study …
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Oncogenetic Panel and Integrated Clinical Data Registry Study for Wild Type Gastrointestinal Stromal Tumor Patients
Clinical trial update on an oncogenetic panel and integrated clinical data registry study in wild-type gastrointestinal stromal tumor patien…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
Ongoing Stanford University clinical trial evaluating clinical and pathological aspects of upper gastrointestinal cancers, including stomach…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Study of Ripretinib vs Sunitinib in Patients With Advanced GIST With Specific KIT Exon Mutations Who Were Previously Treated With Imatinib [Phase 3]
Phase 3 trial comparing ripretinib to sunitinib in adults with advanced gastrointestinal stromal tumor (GIST) harboring KIT exon mutations a…