Gastroesophageal Junction Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: A Prospective Cohort Study on the Treatment of Locally Advanced Gastric Cancer
A prospective cohort study investigating treatments for locally advanced gastric cancer; the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG) [NA]
The LIVELONG trial from University of California, Davis is an ongoing study evaluating locally ablative therapy for oligoprogressive gastroi…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: EPITOME-1015-I: a Study to Investigate the Safety and Tolerability of MDG1015 in Patients with Epithelial Ovarian Cancer, Gastroesophageal Adenocarcinoma, Round Cell Liposarcoma And/or Synovial Sarcoma [Phase 1]
This is a Phase 1 study to evaluate the safety and tolerability of MDG1015 in patients with epithelial ovarian cancer, gastroesophageal junc…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: CYNK-101 in Combination with Trastuzumab and Pembrolizumab in Patients with Locally Advanced Unresectable or Metastatic HER2-Positive Gastric or Gastroesophageal Junction (G/GEJ) Adenocarcinoma [Phase 1, Phase 2]
The clinical trial of CYNK-101 in combination with trastuzumab and pembrolizumab for HER2-positive gastric or gastroesophageal junction canc…
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Anti-HER2 Bispecific Antibody Zanidatamab (ZW25) Activity in Combination With Chemotherapy With/Without Tislelizumab [Phase 1, Phase 2]
Zanidatamab (ZW25) in combination with chemotherapy, with or without tislelizumab, is being evaluated in Phase 1/2 trials for breast cancer,…
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CLINICAL_TRIALS trial_result · 2024-12-02Clinical Trial Update: A Study of IMAB362 in Japanese Subjects With Locally Advanced or Metastatic Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma [NA]
Clinical trial update for IMAB362 (zolbetuximab) in Japanese patients with locally advanced or metastatic gastric or GEJ adenocarcinoma; the…
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FDA approval · 2024-11-22FDA Approved: PHESGO — Supplemental Application (Genentech, Inc.)
FDA approved a supplemental application for PHESGO, the fixed-dose combination of pertuzumab, trastuzumab, and hyaluronidase-zzxf, submitted…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: A Phase 2 Clinical Study of ABSK061 and ABSK043 [Phase 2]
Abbisko Therapeutics is recruiting for a Phase 2 study of ABSK061 and ABSK043 in multiple cancers, including HER2-positive gastric/gastroeso…
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Mecapegfilgrastim Combined With Adebrelimab and Chemotherapy as Neoadjuvant Therapy in Resectable GC/GEJC [Phase 2]
A Phase 2 clinical trial is evaluating mecapegfilgrastim combined with adebrelimab and chemotherapy as neoadjuvant therapy for resectable ga…
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CLINICAL_TRIALS research · 2024-10-28Clinical Trial Update: IMmune Proteomics to Predict neoAdjuvant Chemotherapy and immunoTherapy Response in Gastric Cancer
Clinical trial investigating immune proteomics to predict response to neoadjuvant chemotherapy and immunotherapy in gastric cancer; currentl…
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: BGB A317 in Combination With Chemotherapy as First-Line Treatment in Adults With Inoperable, Locally Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Carcinoma [Phase 2]
Phase 2 trial evaluating BGB-A317 in combination with chemotherapy as first-line treatment for adults with inoperable, locally advanced, or …
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CLINICAL_TRIALS research · 2024-10-22Clinical Trial Update: A Study of MRG002 in Patients with HER2-Positive Advanced Solid Tumors and Locally Advanced or Metastatic Gastric/Gastroesophageal Junction (GEJ) Cancer [Phase 1, Phase 2]
Clinical trial update on MRG002 in patients with HER2-positive advanced solid tumors and locally advanced or metastatic gastric/GEJ cancer, …
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Cadonilimab Combination Regimen as First-line Treatment for HER2-expressing GC/GEJ Patients [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating a Cadonilimab-based combination as first-line therapy for metastatic HER2-expressing gastric or gas…
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: A Study to Investigate Sitravatinib as Monotherapy and in Combination With Tislelizumab in Participants With Unresectable Locally Advanced or Metastatic Hepatocellular Carcinoma or Gastric/Gastroesophageal Junction Cancer [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating sitravatinib as monotherapy and in combination with tislelizumab in participants with unresectable loc…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Phase IIT Trial of SNA014 [EARLY_Phase 1]
Early-phase trial update for SNA014 by SmartNuclide Biopharma targeting gastric and gastroesophageal junction adenocarcinomas; the study is …
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: MRI and CT in Gastroesophageal Junction or Upper Gastric Adenocarcinoma
This clinical trial update describes an imaging study using MRI and CT in patients with gastric cancer or gastroesophageal junction cancer. …
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: Safety and Efficacy of Telatinib in Combination With Keytruda in Subjects With Advanced Stomach and Gastroesophageal Junction Cancers or Hepatocellular Carcinoma [Phase 2]
Phase 2 trial evaluating safety and efficacy of telatinib in combination with pembrolizumab in advanced gastric cancer, gastroesophageal jun…
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CLINICAL_TRIALS research · 2024-10-04Clinical Trial Update: Radical Surgery for Advanced Gastric- or GEJ-cancer With Oligometastatic Dissmination to the Liver [NA]
A clinical trial is evaluating radical surgery for advanced gastric or gastroesophageal junction cancer with limited liver metastases. The s…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: The Efficacy and Safety of LM-302 in Combination With Candonilimab and Capecitabine for First-Line Treatment in Patients With Unresectable Advanced, Recurrent, or Metastatic CLDN18.2-Positive Gastric or Gastroesophageal Junction Adenocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating LM-302 with Candonilimab and capecitabine as first-line therapy for CLDN18.2-positive gastric or GEJ ade…
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: NT-I7 in Combination With Nivolumab in Advanced Gastric, Gastro-Esophageal Junction or Esophageal Adenocarcinoma [Phase 1]
A Phase 1 trial of NT-I7 in combination with nivolumab for advanced gastric, gastroesophageal junction, or esophageal adenocarcinoma has bee…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: A Phase II Trial of Perioperative Adebrelimab Combined With XELOX in Resectable Locally Advanced Gastric/Gastroesophageal Junction Cancer (GC/GEJC) [Phase 2]
This document describes an ongoing Phase II trial investigating perioperative adebrelimab in combination with XELOX for patients with resect…
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CLINICAL_TRIALS research · 2024-07-11Clinical Trial Update: Neoadjuvant Serplulimab in Combination With Chemotherapy in Locally Advanced Gastric or Gastro-esophageal Junction Cancer [Phase 2]
This Phase 2 trial is evaluating neoadjuvant serplulimab with chemotherapy for locally advanced gastric or gastroesophageal junction cancer.…
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CLINICAL_TRIALS research · 2024-06-07Clinical Trial Update: Perioperative Surufatinib Plus Sintilimab Combined With Chemotherapy in Gastric/Gastroesophageal Junction Adenocarcinoma [Phase 2]
Phase 2 clinical trial update evaluating perioperative surufatinib plus sintilimab with chemotherapy for gastric cancer and gastroesophageal…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: A Study Evaluating Safety and Efficacy of Niraparib in Patients With Previously Treated Metastatic Esophageal/Gastroesophageal Junction/Proximal Gastric Adenocarcinoma [Phase 2]
A Phase 2 study evaluating niraparib in previously treated metastatic esophageal, gastroesophageal junction, and proximal gastric adenocarci…
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Adjuvant Treatment With Serplulimab，Trastuzumab and SOX in the HER-2 Positive GC/GEJC [Phase 2]
A Phase 2 clinical trial update evaluating adjuvant therapy with serplulimab, trastuzumab, and the SOX regimen (S-1 plus oxaliplatin) for HE…