Falciparum Malaria
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2015-11-03Clinical Trial Update: Arterolane-PQP Versus DHA-PQP in Uncomplicated Falciparum Malaria in Eastern Myanmar [Phase 2, Phase 3]
This clinical trial comparing Arterolane-PQP to DHA-PQP for uncomplicated falciparum malaria in eastern Myanmar has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-05-19Clinical Trial Update: Effectiveness of the Association Artesunate and Mefloquine in the Treatment of Malaria by Plasmodium Falciparum [Phase 2, Phase 3]
Phase 2/3 trial update evaluating the effectiveness of artesunate plus mefloquine for treatment of falciparum malaria.
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CLINICAL_TRIALS trial_result · 2015-04-13Clinical Trial Update: Safety and Efficacy Study of Adjunctive Rosiglitazone in the Treatment of Uncomplicated Falciparum Malaria [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating the safety and potential efficacy of adding rosiglitazone to standard treatment for uncomplicated fal…
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CLINICAL_TRIALS research · 2015-01-22Clinical Trial Update: Evaluation of Volume Status, Haemodynamics and Microcirculatory Flow in Adult Patients With Severe Falciparum Malaria
A University of Oxford-sponsored clinical trial evaluating volume status, haemodynamics, and microcirculatory flow in adults with severe fal…
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CLINICAL_TRIALS withdrawal · 2014-11-13Clinical Trial Update: Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine or Chloroquine/Azithromycin Prophylaxis [Phase 1, Phase 2]
A Phase 1/2 clinical trial of immunization with Plasmodium falciparum sporozoites under chloroquine or chloroquine/azithromycin prophylaxis …
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CLINICAL_TRIALS trial_result · 2014-08-19Clinical Trial Update: Sevuparin/DF02 as an Adjunctive Therapy in Subjects Affected With Uncomplicated Falciparum Malaria [Phase 1, Phase 2]
This document reports the termination of a Phase 1/2 clinical trial evaluating Sevuparin/DF02 as an adjunctive therapy for uncomplicated fal…
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CLINICAL_TRIALS trial_result · 2014-05-28Clinical Trial Update: Artemether/ Lumefantrine: A Study of the Effect of Local Food on Pharmacokinetics and Population Pharmacokinetics [Phase 4]
Phase 4 pharmacokinetic study evaluating how local food affects artemether/lumefantrine exposure and population pharmacokinetics in malaria …
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CLINICAL_TRIALS trial_result · 2013-06-07Clinical Trial Update: Study of Iron Absorption and Utilization in Asymptomatic Malaria [EARLY_Phase 1]
This document provides an update on an early-phase 1 clinical trial evaluating iron absorption and utilization in asymptomatic Plasmodium fa…
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CLINICAL_TRIALS trial_result · 2013-02-13Clinical Trial Update: Re-exposure of Human Volunteers to a Heterologous Strain of P. Falciparum Sporozoites [NA]
The trial assessing re-exposure of volunteers to a heterologous Plasmodium falciparum sporozoite strain has completed.
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CLINICAL_TRIALS trial_result · 2012-09-27Clinical Trial Update: Assessing the Efficacy of Four Drug Combinations as the Next First-line Therapy for Uncomplicated Malaria in Malawi [Phase 4]
Phase 4 clinical trial in Malawi evaluated four drug combinations as the next first-line therapy for uncomplicated falciparum malaria; the s…
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CLINICAL_TRIALS trial_result · 2012-07-12Clinical Trial Update: Artesunate+Sulfadoxine-Pyrimethamine for the Treatment of Uncomplicated Falciparum Malaria
Clinical trial update on artesunate plus sulfadoxine-pyrimethamine for uncomplicated falciparum malaria. The study status is completed.
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CLINICAL_TRIALS trial_result · 2011-06-17Clinical Trial Update: Safety Study on the Effect of Eurartesim™ on QT/QTc Interval Compared to Riamet in Healthy Volunteers [Phase 1]
Phase 1 safety study comparing QT/QTc interval effects between Eurartesim and Riamet in healthy volunteers has completed.
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CLINICAL_TRIALS trial_result · 2011-05-11Clinical Trial Update: Azithromycin Plus Chloroquine Versus Atovaquone-Proguanil For The Treatment Of Uncomplicated Plasmodium Falciparum Malaria In South America [Phase 2, Phase 3]
A completed Phase 2/3 randomized trial comparing azithromycin plus chloroquine with atovaquone-proguanil for uncomplicated falciparum malari…
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CLINICAL_TRIALS trial_result · 2011-05-11Clinical Trial Update: Azithromycin Plus Chloroquine Versus Mefloquine for the Treatment of Uncomplicated Malaria in Africa [Phase 2, Phase 3]
This update reports the completion of a Phase 2/3 trial comparing azithromycin plus chloroquine against mefloquine for uncomplicated falcipa…
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CLINICAL_TRIALS trial_result · 2011-01-25Clinical Trial Update: Artemisinin Resistance in Cambodia II [NA]
A completed clinical trial update from the Armed Forces Research Institute of Medical Sciences on artemisinin resistance in falciparum malar…
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CLINICAL_TRIALS trial_result · 2011-01-14Clinical Trial Update: Efficacy of ArTiMist™ in Children [Phase 2]
A Phase 2 study evaluated the efficacy of ArTiMist™ in children with falciparum malaria. The trial has completed and results were posted on …
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CLINICAL_TRIALS trial_result · 2011-01-04Clinical Trial Update: Chloroquine and Coartem for Treatment of Symptomatic Children With Plasmodium Falciparum in Guinea Bissau [Phase 4]
A Phase 4 trial evaluating chloroquine and artemether-lumefantrine (Coartem) for treating symptomatic Plasmodium falciparum malaria in child…
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CLINICAL_TRIALS trial_result · 2010-06-25Clinical Trial Update: Bioequivalence Study Comparing Artesunate Tablet To Arsuamoon® Tablets (Guilin-China) In Healthy Subjects [Phase 1]
Pfizer-sponsored Phase 1 bioequivalence study in healthy subjects completed, comparing Artesunate tablets with Arsuamoon tablets in Guilin, …
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CLINICAL_TRIALS trial_result · 2010-04-21Clinical Trial Update: A Bioequivalence Study Comparing Amodiaquine Tablet (Pfizer) To Amodiaquine Tablets (Arsuamoon-Guilin China) In Healthy Subjects [Phase 1]
This Phase 1 bioequivalence study compared amodiaquine tablets from Pfizer with a marketed amodiaquine formulation (Arsuamoon) in healthy vo…
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CLINICAL_TRIALS trial_result · 2009-11-25Clinical Trial Update: Extended-dose Chloroquine (ECQ) for Resistant Falciparum Malaria Among Afghan Refugees in Pakistan [Phase 4]
A Phase 4 trial evaluated extended-dose chloroquine for resistant falciparum malaria among Afghan refugees in Pakistan. The study has comple…
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CLINICAL_TRIALS trial_result · 2008-11-03Clinical Trial Update: Azithromycin Plus Chloroquine Versus Sulfadoxine-Pyrimethamine Plus Chloroquine For The Treatment Of Uncomplicated, Symptomatic Falciparum Malaria In Southeast Asia [Phase 2, Phase 3]
Pfizer conducted a Phase 2/3 trial comparing azithromycin plus chloroquine to sulfadoxine-pyrimethamine plus chloroquine for uncomplicated F…
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CLINICAL_TRIALS trial_result · 2008-08-13Clinical Trial Update: Mass-Drug Administration to Reduce Malaria Transmission [NA]
A completed clinical trial evaluating mass-drug administration to reduce transmission of falciparum malaria.
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CLINICAL_TRIALS trial_result · 2008-06-02Clinical Trial Update: Arginine Malaria Trial: Study of Adjunctive Arginine in Falciparum Malaria [Phase 1, Phase 2]
The document indicates the completion of a Phase 1/Phase 2 clinical trial evaluating adjunctive L-arginine in falciparum malaria.
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CLINICAL_TRIALS trial_result · 2008-04-08Clinical Trial Update: Chloroquine and Amodiaquine for Treatment of Malaria in Children [Phase 4]
Phase 4 trial update on chloroquine and amodiaquine for falciparum malaria in children; the study has completed.
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CLINICAL_TRIALS trial_result · 2008-03-26Clinical Trial Update: The Impact of Artemether-Lumefantrine on Genes Associated With Antimalarial Resistance
The completed trial update analyzes how artemether-lumefantrine affects genes associated with antimalarial resistance in falciparum malaria.