Falciparum Malaria
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: The Impact RTS,S/AS01 Vaccine in School Aged Children RTS,S/AS01 Malaria Vaccine in School Aged Children [Phase 4]
Clinical trial update for the RTS,S/AS01 malaria vaccine in school-aged children; a Phase 4 study currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-03-29Clinical Trial Update: Seasonal Malaria Chemoprevention Rapid Assessment Study Mozambique [Phase 4]
Phase 4 trial update on seasonal malaria chemoprevention in Mozambique under Malaria Consortium.
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: Reducing the Risk of P. Vivax After Falciparum Infections in Co-endemic Areas [Phase 4]
Phase 4 clinical trial evaluating strategies to reduce risk of Plasmodium vivax after Plasmodium falciparum infections in co-endemic areas, …
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CLINICAL_TRIALS trial_result · 2023-08-03Clinical Trial Update: A Study to Determine if a New Malaria Vaccine is Safe and Induces Immunity Among Kenyan Adults, Young Children and Infants [Phase 1, Phase 2]
A multicenter early-phase trial evaluating safety and immunogenicity of a new malaria vaccine in Kenyan adults, children, and infants has co…
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CLINICAL_TRIALS trial_result · 2023-03-07Clinical Trial Update: Seasonal Malaria Chemoprevention With Dihydroartemisin Piperaquin vs. Sulfadoxine-pyrimethamin+Amodiaquin [Phase 3]
Phase 3 trial update comparing dihydroartemisinin-piperaquine versus sulfadoxine-pyrimethamine+amodiaquine for seasonal malaria chemoprevent…
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CLINICAL_TRIALS trial_result · 2023-02-23Clinical Trial Update: TES of Artemether-lumefantrine for Pf and Chloroquine for Pv in the Philippines From 2013-2014
A completed clinical trial update investigating artemether-lumefantrine for Plasmodium falciparum and chloroquine for Plasmodium vivax malar…
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CLINICAL_TRIALS trial_result · 2022-02-24Clinical Trial Update: Adjunctive Ivermectin Mass Drug Administration for Malaria Control [Phase 3]
Phase 3 clinical trial update on adjunctive ivermectin MDA for malaria control and related neglected tropical diseases.
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CLINICAL_TRIALS trial_result · 2022-01-18Clinical Trial Update: Gametocytocidal and Transmission-blocking Efficacy of PQ in Combination With AL and TQ in Combination With SPAQ in Mali [Phase 2]
Phase 2 clinical trial evaluating gametocytocidal and transmission-blocking efficacy of PQ with AL and TQ with SPAQ in malaria patients in M…
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CLINICAL_TRIALS trial_result · 2021-09-17Clinical Trial Update: Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria Patients [Phase 3]
Phase 3 trial comparing pyronaridine-artesunate (3:1) to mefloquine-artesunate in falciparum malaria has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-09-05Clinical Trial Update: Study in Blood Stage Malaria Infection After DVI of Cryopreserved P. Falciparum (NF54 Strain) Sporozoites [Phase 1]
Phase 1 clinical trial investigating blood-stage malaria infection after direct venous inoculation of cryopreserved Plasmodium falciparum NF…
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CLINICAL_TRIALS trial_result · 2021-04-02Clinical Trial Update: Efficacy and Safety of Artesunate-amodiaquine and Artemether-lumefantrine for the Treatment of Malaria in Cameroon [Phase 4]
A Phase 4 trial update assessing efficacy and safety of artesunate-amodiaquine and artemether-lumefantrine for falciparum malaria in Cameroo…
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CLINICAL_TRIALS trial_result · 2021-04-02Clinical Trial Update: Effectiveness and Safety of Artesunate-Amodiaquine and Artemether-Lumefantrine for the Treatment of Malaria in Yaounde [Phase 4]
Phase 4 trial evaluating effectiveness and safety of artesunate-amodiaquine and artemether-lumefantrine for treating malaria in Yaounde, com…
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CLINICAL_TRIALS trial_result · 2020-06-09Clinical Trial Update: MMV390048 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Participants [Phase 1]
Phase 1 trial evaluating MMV390048 for early blood-stage infection of Falciparum malaria in healthy participants; study terminated with resu…
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CLINICAL_TRIALS trial_result · 2020-03-31Clinical Trial Update: Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2 [NA]
A completed clinical trial evaluating transmission-blocking interventions using a controlled human malaria infection model in malaria falcip…
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CLINICAL_TRIALS trial_result · 2020-03-25Clinical Trial Update: Methylene Blue Against Falciparum Malaria in Burkina Faso [Phase 2]
Phase 2 trial evaluating methylene blue for falciparum malaria completed in Burkina Faso with results posted.
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CLINICAL_TRIALS trial_result · 2018-05-09Clinical Trial Update: A Study by the Tracking Resistance to Artemisinin Collaboration (TRAC) [Phase 2, Phase 3]
This update notes the completion of Phase 2 and Phase 3 trials conducted by the TRAC collaboration on falciparum malaria.
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CLINICAL_TRIALS trial_result · 2018-05-04Clinical Trial Update: Clinical Investigation of In-vivo Susceptibility of P.Falciparum to Artesunate in Western Cambodia [NA]
This clinical trial evaluated the in-vivo susceptibility of Plasmodium falciparum to artesunate in western Cambodia and the study is complet…
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CLINICAL_TRIALS research · 2018-04-27Clinical Trial Update: Evaluation of the Performance of a hsRDT Versus cRDT in Reactive Case Detection of Malaria Infections [NA]
This clinical trial compares the performance of a highly sensitive rapid diagnostic test (hsRDT) to a conventional rapid diagnostic test (cR…
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CLINICAL_TRIALS trial_result · 2018-03-27Clinical Trial Update: "Prolonging the Therapeutic Life Span of Artemisinin-based Combination Therapies (ACT) in Bagamoyo District, Tanzania" [Phase 4]
A Phase 4 clinical trial conducted in Tanzania aims to prolong the therapeutic life span of artemisinin-based combination therapies for falc…
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CLINICAL_TRIALS trial_result · 2017-01-26Clinical Trial Update: Study of the Impact of Intermittent Preventive Treatment in Schools on Malaria, Anaemia and Education. [Phase 3]
A Phase 3 trial evaluating intermittent preventive treatment in schoolchildren for falciparum malaria and related anemia has completed.
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: ACT With Chloroquine, Amodiaquine & Sulphadoxine-pyrimethamine in Pakistan [Phase 3]
Phase 3 clinical trial update examining a combination of chloroquine, amodiaquine, and sulfadoxine-pyrimethamine for malaria in Pakistan. Th…
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CLINICAL_TRIALS trial_result · 2017-01-12Clinical Trial Update: Preventing Malaria During Pregnancy in Epidemic-prone Areas. [Phase 3]
Phase 3 clinical trial update on preventing malaria in pregnant women in epidemic-prone areas; the study has completed. The snippet does not…
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: Chlorproguanil-Dapsone-Artesunate (CDA) Versus Chlorproguanil-Dapsone (LAPDAP) For Uncomplicated Malaria [Phase 3]
A Phase 3 trial comparing Chlorproguanil-Dapsone-Artesunate (CDA) to Chlorproguanil-Dapsone (LAPDAP) for uncomplicated falciparum malaria ha…
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CLINICAL_TRIALS trial_result · 2016-08-23Clinical Trial Update: Safety and Tolerability of Low Dose Primaquine [Phase 4]
Phase 4 trial update evaluating the safety and tolerability of a low-dose primaquine regimen for falciparum malaria, including consideration…
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CLINICAL_TRIALS trial_result · 2015-11-30Clinical Trial Update: Time to Become Negative of Three Rapid Diagnostic Tests for Malaria
A completed clinical trial evaluating the time to negativity for three rapid diagnostic tests used to detect falciparum malaria.