Esophageal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS other · 2026-02-18Clinical Trial Update: SYS6010 Versus Chemotherapy in Locally Advanced or Metastatic/Recurrent Esophageal Squamous Cell Carcinoma [Phase 3]
Clinical trial comparing SYS6010 against chemotherapy in locally advanced or metastatic/recurrent esophageal squamous cell carcinoma; the st…
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CLINICAL_TRIALS withdrawal · 2026-02-17Clinical Trial Update: S095033 in Combination With Paclitaxel as 2nd- or 3rd-line Treatment in Participants With Advanced or Metastatic ESCC [Phase 1, Phase 2]
This clinical trial update indicates that the phase 1/2 study of S095033 in combination with paclitaxel for advanced or metastatic esophagea…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: A Study to Investigate the Safety and Tolerability of Intravenous QEQ278 in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study of intravenous QEQ278 in patients with advanced solid tumors has been terminated.
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors [Phase 1]
Phase 1 study update for NRM-823 in locally advanced or metastatic refractory solid tumors, currently recruiting. The trial lists head and n…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: Short-course Radiotherapy Combined With Serplulimab and Chemotherapy as Neoadjuvant Treatment for Resectable ESCC [Phase 2]
A Phase 2 clinical trial evaluating short-course radiotherapy in combination with serplulimab and chemotherapy as neoadjuvant therapy for re…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Real-world Experience of ICIs Plus Chemotherapy for Advanced ESCC.
A completed real-world study examining immune checkpoint inhibitors combined with chemotherapy for advanced/metastatic esophageal squamous c…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: DCRT vs. Surgery in Resectable ESCC Patient Achiving cCR/PR After nCI [Phase 2]
Phase 2 trial comparing definitive chemoradiation therapy versus surgery in patients with resectable esophageal squamous cell carcinoma who …
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Neoadjuvant Chemoimmunotherapy or Chemoradiotherapy in ESCC [Phase 2]
Phase 2 trial exploring neoadjuvant chemoimmunotherapy or chemoradiotherapy for resectable esophageal squamous cell carcinoma; status is NOT…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Adebrelimab Neoadjuvant Treatment for Resectable ESCC [NA]
The document reports a clinical trial evaluating adebrelimab as neoadjuvant therapy for resectable esophageal squamous cell carcinoma, with …
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC [Phase 1, Phase 2]
This is a multicenter Phase Ib/II trial evaluating Ivonescimab (AK112) in combination with albumin-bound paclitaxel and cisplatin as neoadju…
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation [Phase 1]
A Phase 1 study of PRT7732, an oral SMARCA2 degrader, in patients with SMARCA4-mutant advanced or metastatic solid tumors has been terminate…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Chemoradiotherapy Following Immunotherapy Plus Chemotherapy for Locally-advanced Esophageal Squamous Cell Cancer (RICE) [Phase 2]
Phase 2 clinical trial evaluating sequential treatment with immunotherapy plus chemotherapy followed by chemoradiotherapy for locally-advanc…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Neoadjuvant Treatment of Toripalimab Combined With Nab-paclitaxel and Platinum Versus Neoadjuvant Docetaxel Combined With Cisplatin and 5-fluorouracil (DCF) in Esophageal Squamous Cell Carcinoma [Phase 3]
A Phase 3 clinical trial compares neoadjuvant toripalimab plus nab-paclitaxel and platinum against neoadjuvant docetaxel with cisplatin and …
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Indocyanine Green-guided Omental Shield Anastomosis for Cervical Esophagogastric Anastomosis in Minimally Invasive McKeown Esophagectomy [Phase 2]
Phase 2 clinical trial evaluating indocyanine green-guided omental shield anastomosis during cervical esophagogastric anastomosis in minimal…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Study of Durvalumab Versus Placebo in Combination With Definitive Chemoradiation Therapy in Patient With ESCC [Phase 3]
Phase 3 clinical trial comparing durvalumab plus definitive chemoradiation versus placebo with chemoradiation for esophageal squamous cell c…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Ipromlimab and Tuvonralimab Combined With Albumin-Bound Paclitaxel and Nedaplatin as Neoadjuvant Therapy for Locally Advanced Resectable Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 trial update on neoadjuvant therapy combining ipromlimab and tuvonralimab with albumin-bound paclitaxel and nedaplatin for locally a…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Registry Platform Gastric/Esophageal Cancer (SAPHIR)
This Clinical Trial Update reports an ongoing registry platform trial SAPHIR addressing gastric and esophageal cancers, currently recruiting…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Neoadjuvant Immunochemotherapy and Chemoradiotherapy Followed by Surgery for Advanced Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial conducted by National Taiwan University Hospital evaluating neoadjuvant immunochemotherapy and chemoradiotherapy foll…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Based on ctDNA-MRD Guided Adjuvant Treatment Escalation After Definitive Chemoradiotherapy for Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma: a Study on Safety and Efficacy [EARLY_Phase 1]
A Phase 1 trial assessing the safety and potential efficacy of ctDNA MRD-guided escalation of adjuvant therapy after definitive chemoradioth…
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EMA approval · 2026-01-26EMA Authorised: Tevimbra (tislelizumab) — Beone Medicines Ireland Limited
EMA authorised Tevimbra (tislelizumab) from Beone Medicines Ireland Limited for multiple cancer indications, including esophageal squamous c…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Impact of Preserving Versus Ligating the Right Gastric Artery on Anastomotic Outcomes After McKeown Esophagectomy: A Randomized Controlled Trial [NA]
This completed randomized trial evaluated whether preserving versus ligating the right gastric artery affects anastomotic outcomes after McK…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: MR-Guided Radiotherapy Dose Escalation Trial for Esophageal Squamous Cell Carcinoma [Phase 1]
Phase 1 trial evaluating MR-guided radiotherapy dose escalation for esophageal squamous cell carcinoma, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Radiotherapy Combined With Immunochemotherapy in Metastatic Esophageal Squamous Cell Carcinoma [Phase 2]
This is an update on an ongoing Phase 2 clinical trial evaluating radiotherapy combined with immunochemotherapy for metastatic esophageal sq…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400 [Phase 1]
Phase 1 study assessing adverse events and change in disease activity in adults with select advanced solid tumors treated with ABBV-400; the…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Standardized Management of Esophageal Fistula in Esophageal Squamous Cell Carcinoma
This clinical trial update describes standardized management strategies for esophageal fistula in patients with esophageal squamous cell car…