Esophageal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Multicenter Prospective Cohort on Esophageal Endoscopic Submucosal Dissection
A multicenter prospective cohort study evaluating esophageal endoscopic submucosal dissection for superficial esophageal cancer and Barrett'…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Intestinal Low-Dose Radiotherapy Plus Immunochemotherapy for Conversion of Borderline Resectable/Unresectable Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating intestinal low-dose radiotherapy plus immunochemotherapy, including tislelizumab, to convert borderline …
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Trial of Nivolumab and Cetuximab After Chemoradiation in Esophageal Squamous Cell Carcinoma Patients. [Phase 2]
This update covers a Phase 2 trial evaluating nivolumab in combination with cetuximab after chemoradiation for esophageal squamous cell carc…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: A Phase II Clinical Study to Evaluate HLX43 in Patients With Recurrent/Metastatic ESCC Failed or Intolerance to Standard Therapy [Phase 2]
Phase II clinical study evaluating HLX43 in patients with recurrent/metastatic esophageal squamous cell carcinoma who failed or were intoler…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01) [Phase 3]
Phase 3 study evaluating Ifinatamab Deruxtecan in patients with pretreatment advanced or metastatic Esophageal Squamous Cell Carcinoma is cu…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors [Phase 1, Phase 2]
A first-in-human Phase 1/2 trial of JAB-8263 in adults with advanced tumors is currently recruiting across multiple cancer types including l…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy
A clinical trial update describing a multi-omic assessment of squamous cell cancers receiving systemic therapy; currently active but not rec…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Chemoradiation Plus Iparomlimab Consolidation in Older With ESCC [Phase 2]
Phase 2 trial evaluating chemoradiation with consolidation iparomlimab in older adults with esophageal cancer (esophageal squamous cell carc…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Neoadjuvant Immunotherapy Combined With Chemotherapy Sequenced With Endoscopic Resection for Esophageal Cancer (Endosurgery-02) [Phase 1]
This Phase 1 clinical trial evaluates neoadjuvant immunotherapy combined with chemotherapy followed by endoscopic resection for esophageal s…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Nimotuzumab,Camrelizumab, and Neoadjuvant Chemotherapy（nCT） in the Treatment of Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating nimotuzumab plus camrelizumab with neoadjuvant chemotherapy for esophageal squamous cell carcinoma; the st…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Perioperative Cadonilimab Combined With Neoadjuvant Chemotherapy in Resectable Esophageal Squamous Cell Carcinoma (ESCC) [Phase 2]
A Phase 2 clinical trial is evaluating perioperative cadonilimab in combination with neoadjuvant chemotherapy for resectable esophageal squa…
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors [Phase 1]
First-in-human Phase 1 study of JAB-3312 in adults with advanced solid tumors has been completed, evaluating multiple tumor indications.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: The Efficacy and Safety of Iparomlimab and Tuvonralimab Injection Combined With Chemotherapy as the First-line Treatment for Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of combining Iparomlimab and Tuvonralimab with chemotherapy as first-line treatmen…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Study of Combination Therapies With or Without Pembrolizumab (MK-3475) and/or Chemotherapy in Participants With Advanced Esophageal Cancer (MK-3475-06A) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating pembrolizumab with or without chemotherapy in advanced esophageal squamous cell carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: A Study of SGN-B6A in Chinese Participants With Advanced Solid Tumors [Phase 1]
A Phase 1 study of SGN-B6A in Chinese participants with advanced solid tumors has completed, reporting safety and preliminary activity acros…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Plus Chemotherapy in Participants With Metastatic Esophageal Carcinoma (MK-7902-014/E7080-G000-320/LEAP-014) [Phase 3]
Phase 3 trial evaluating pembrolizumab plus lenvatinib and chemotherapy in metastatic esophageal squamous cell carcinoma; the study status i…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: A Phase II Study of Toripalimab Plus Chemotherapy and Low-Dose Radiotherapy for Neoadjuvant Therapy-Refractory Esophageal Squamous Cell Carcinoma [Phase 2]
This is a Phase II trial evaluating toripalimab in combination with chemotherapy and low-dose radiotherapy as neoadjuvant therapy for esopha…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Oncolytic Virus in Esophageal Squamous Cell Carcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating an oncolytic virus therapy for esophageal squamous cell carcinoma is currently recruiting, sponsored b…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Integrated Cf-miRNA and Exosomal miRNA Signature for Early Detection of Esophageal Squamous Cell Carcinoma
A clinical trial evaluating a combined cf-miRNA and exosomal miRNA signature for early detection of esophageal squamous cell carcinoma (ESCC…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Efficacy and Safety of Neoadjuvant Envafolimab Combined With Albumin-bound Paclitaxel and Carboplatin for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase 2 trial evaluating neoadjuvant envafolimab in combination with albumin-bound paclitaxel and carboplatin for resectable locally advan…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Clinical Study of Adbelimumab in the Adjuvant Treatment of Esophageal Squamous Cell Carcinoma. [Phase 2]
Phase 2 clinical trial investigating Adbelimumab as adjuvant therapy for esophageal squamous cell carcinoma; currently recruiting.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program [Phase 2]
Phase 2 trial evaluating in-home versus in-clinic subcutaneous nivolumab administration under the CC Beyond Walls program; the study is curr…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: A Phase I Clinical Study of Recombinant Humanized Anti-BTLA Monoclonal Antibody (JS004) Injection Combined With Toripalimab Injection in Patients With Advanced Solid Tumors [Phase 1]
A Phase I trial of JS004, a recombinant humanized anti-BTLA monoclonal antibody, in combination with toripalimab for advanced solid tumors h…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: A Trial of the Combination of Afatinib and Palbociclib in Previously Treated Advanced Esophageal Squamous Cell Carcinoma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the combination of afatinib and palbociclib in previously treated advanced esophageal squamous cell carc…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Circulating Tumor DNA MRD-Guided Adjuvant Therapy for Curatively Resected Locally Advanced Esophageal Squamous Cell Carcinoma [Phase 3]
Phase 3 clinical trial evaluating circulating tumor DNA MRD-guided adjuvant therapy after curative resection of locally advanced esophageal …