Esophageal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-22Clinical Trial Update: Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975) [Phase 3]
Phase 3 trial examining pembrolizumab plus chemoradiation versus placebo in esophageal cancer has completed.
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CLINICAL_TRIALS trial_result · 2026-07-20Clinical Trial Update: Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Plus Chemotherapy in Participants With Metastatic Esophageal Carcinoma (MK-7902-014/E7080-G000-320/LEAP-014) [Phase 3]
Phase 3 trial evaluating pembrolizumab plus lenvatinib and chemotherapy in metastatic esophageal squamous cell carcinoma has completed with …
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CLINICAL_TRIALS trial_result · 2026-07-20Clinical Trial Results: Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Plus Chemotherapy in Participants With Metastatic Esophageal Carcinoma (MK-7902-014/E7080-G000-320/LEAP-014) [Phase 3]
Phase 3 trial evaluating pembrolizumab plus lenvatinib plus chemotherapy in metastatic esophageal squamous cell carcinoma completed with pos…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Comparison of Nab-Paclitaxel Versus Paclitaxel in Neoadjuvant Immunochemotherapy Therapy for Esophageal Squamous Cell Carcinoma: A Retrospective IPTW-Adjusted Analysis
A retrospective IPTW-adjusted analysis compares nab-paclitaxel versus paclitaxel in neoadjuvant immunochemotherapy for esophageal squamous c…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: A First in Human Study of ALX2004 With Advanced or Metastatic Selected Solid Tumors [Phase 1]
This first-in-human Phase 1 trial update reports ALX2004 for advanced or metastatic solid tumors and notes that the study is currently recru…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Consolidation of Toripalimab and Capecitabine After Chemoradiotherapy in ESCC [Phase 3]
A Phase 3 trial evaluating consolidation with toripalimab plus capecitabine after chemoradiotherapy in esophageal squamous cell carcinoma is…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Phase II Study Evaluating Safety and Efficacy of Tislelizumab for Elderly Patients Unfit for Chemotherapy, With Advanced Esophageal Squamous-cell Carcinoma [Phase 2]
Phase II clinical trial evaluating safety and efficacy of tislelizumab in elderly patients with advanced esophageal squamous cell carcinoma …
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Dose Finding Study of TNO155 in Adult Patients With Advanced Solid Tumors [Phase 1]
Novartis' Phase 1 dose-finding trial of TNO155 in adults with advanced solid tumors has been terminated. No efficacy results are provided in…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Vebrekotuzumab ± Anti-PD-1 in Pretreated Advanced ESCC [Phase 2]
Phase 2 trial of Vebrekotuzumab with or without an anti-PD-1 antibody for pretreatment advanced esophageal squamous cell carcinoma has been …
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Study to Investigate Tislelizumab (BGB-A317) Versus Placebo in Combination With Concurrent Chemoradiotherapy in Participants With Localized Esophageal Squamous Cell Carcinoma [Phase 3]
A Phase 3 trial comparing tislelizumab plus concurrent chemoradiotherapy versus placebo with chemoradiotherapy in localized esophageal squam…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: A Trial of ChAdOx1 and MVA Vaccines Against MAGE-A3 and NY-ESO-1 [Phase 1, Phase 2]
A Phase 1/2 trial evaluating ChAdOx1 and MVA vaccines targeting MAGE-A3 and NY-ESO-1 for non-small cell lung cancer and esophageal squamous …
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Study of Lomvastomig (RO7121661) and Tobemstomig (RO7247669) Compared With Nivolumab in Participants With Advanced or Metastatic Squamous Cell Carcinoma of the Esophagus [Phase 2]
Phase 2 trial comparing Roche investigational agents Lomvastomig and Tobemstomig with nivolumab in advanced or metastatic esophageal squamou…
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Development and Multicenter Validation of a Novel Bio-Anatomical Staging System for Predicting Survival and Tailoring Adjuvant Therapy in ESCC After Neoadjuvant Chemoimmunotherapy.
A completed multicenter study validates a novel bio-anatomical staging system to predict survival and tailor adjuvant therapy for esophageal…
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Study of MRI Guided Personal Chemoradiotherapy and Immunotherapy for Limited Advanced Esophageal Squamous Caicinoma. [Phase 2]
Clinical trial update for a Phase 2 study of MRI-guided personalized chemoradiotherapy plus immunotherapy for limited advanced unresectable …
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: A Study to Investigate the Safety and Tolerability of Intravenous QEQ278 in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study of intravenous QEQ278 in patients with advanced solid tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation [Phase 1]
A Phase 1 study of PRT7732, an oral SMARCA2 degrader, in patients with SMARCA4-mutant advanced or metastatic solid tumors has been terminate…
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: Ipromlimab and Tuvonralimab Combined With Albumin-Bound Paclitaxel and Nedaplatin as Neoadjuvant Therapy for Locally Advanced Resectable Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 trial update on neoadjuvant therapy combining ipromlimab and tuvonralimab with albumin-bound paclitaxel and nedaplatin for locally a…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Impact of Preserving Versus Ligating the Right Gastric Artery on Anastomotic Outcomes After McKeown Esophagectomy: A Randomized Controlled Trial [NA]
This completed randomized trial evaluated whether preserving versus ligating the right gastric artery affects anastomotic outcomes after McK…
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CLINICAL_TRIALS trial_result · 2025-12-29Clinical Trial Update: A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors [Phase 1]
First-in-human Phase 1 study of JAB-3312 in adults with advanced solid tumors has been completed, evaluating multiple tumor indications.
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: A Study of SGN-B6A in Chinese Participants With Advanced Solid Tumors [Phase 1]
A Phase 1 study of SGN-B6A in Chinese participants with advanced solid tumors has completed, reporting safety and preliminary activity acros…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: A Phase I Clinical Study of Recombinant Humanized Anti-BTLA Monoclonal Antibody (JS004) Injection Combined With Toripalimab Injection in Patients With Advanced Solid Tumors [Phase 1]
A Phase I trial of JS004, a recombinant humanized anti-BTLA monoclonal antibody, in combination with toripalimab for advanced solid tumors h…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Circulating Tumor DNA MRD-Guided Adjuvant Therapy for Curatively Resected Locally Advanced Esophageal Squamous Cell Carcinoma [Phase 3]
Phase 3 clinical trial evaluating circulating tumor DNA MRD-guided adjuvant therapy after curative resection of locally advanced esophageal …
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Study of Tislelizumab in Participants With Resectable Esophageal Squamous Cell Carcinoma [Phase 2]
BeiGene's tislelizumab was evaluated in a Phase 2 trial in patients with resectable esophageal squamous cell carcinoma; the study has comple…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Neoadjuvant Immunochemotherapy vs Chemoradiotherapy in ESCC [NA]
A clinical trial update indicates that a study comparing neoadjuvant immunochemotherapy to chemoradiotherapy in esophageal squamous cell car…
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer [Phase 2]
Phase II trial evaluating the effect of itraconazole on pathologic complete response rates in resectable esophageal cancer is currently recr…