Esophageal Squamous Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: QLC5508 vs. Chemotherapy in Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma [Phase 3]
A Phase 3 trial evaluating QLC5508 versus standard chemotherapy in pretreated advanced or metastatic esophageal squamous cell carcinoma is c…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Clinical Trial of Ifinatamab Deruxtecan in People With Advanced Esophageal Cancer (MK-3475-06F) [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial evaluating Ifinatamab Deruxtecan in patients with advanced esophageal squamous cell carcinoma; the study …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: TPF Concurrent Chemo-radiotherapy Plus Immunotherapy for Local Advanced Esophageal Squamous Cell Carcinoma [NA]
A clinical trial from Fudan University is evaluating TPF-based concurrent chemoradiotherapy with immunotherapy for locally advanced esophage…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Neoadjuvant Ivonescimab（AK112） Combined With Chemotherapy in Patients With Resectable Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 neoadjuvant trial evaluating Ivonescimab (AK112) plus chemotherapy in patients with resectable esophageal squamous cell carcinoma; t…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Efficacy and Safety of Tislelizumab Plus Chemotherapy as Conversion Therapy in Unresectable Locally Advanced ESCC
A clinical trial is evaluating tislelizumab plus chemotherapy as conversion therapy for unresectable locally advanced esophageal squamous ce…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study Evaluating the Safety and Efficacy of JS212 Combination Therapy in Patients With Advanced Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating JS212 combination therapy for advanced esophageal squamous cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study of Sigvotatug Vedotin in Advanced Solid Tumors [Phase 1]
Phase 1 study of Sigvotatug Vedotin in advanced solid tumors is currently recruiting. The trial targets multiple indications, including non-…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy [Phase 3]
Phase 3 study evaluating atezolizumab with or without tiragolumab in unresectable esophageal squamous cell carcinoma after definitive chemor…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study Comparing BL-B01D1 With Chemotherapy of Physician's Choice in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma(PANKU-Esophagus01) [Phase 3]
Phase 3 study updating BL-B01D1 vs physician's choice chemotherapy in recurrent or metastatic esophageal squamous cell carcinoma; the trial …
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Tpex Subsets in Negative Tumor Draining Lymph Nodes for Predicting the Efficacy of PD 1 Inhibitors in Advanced or Recurrent Esophageal Squamous Cell Carcinoma
A clinical trial update from Fudan University describes evaluating Tpex T-cell subsets in negative tumor-draining lymph nodes to predict how…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Efficacy and Safety of QL1706 Combined With Nab-paclitaxel and Cisplatin as 1st Line Therapy for Advanced or Metastatic Esophageal Squamous Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating QL1706 in combination with nab-paclitaxel and cisplatin as first-line therapy for advanced or metastatic e…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Prospective, Open-label, Multi-cohort Study of Becotatug Vedotin With Tislelizumab and Chemotherapy in Esophageal Squamous Cell Carcinoma - Phase 2 [Phase 2]
A Phase 2 open-label, multi-cohort study evaluating Becotatug Vedotin in combination with Tislelizumab and chemotherapy for esophageal squam…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Intensive Nutritional Support in Conversion Therapy for Locally Advanced Unresectable ESCC [Phase 2]
Phase 2 clinical trial update for intensive nutritional support as conversion therapy in locally advanced unresectable esophageal squamous c…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Study of XB010 in Subjects With Solid Tumors [Phase 1]
A Phase 1 trial evaluating XB010 in locally advanced or metastatic solid tumors is currently recruiting across multiple indications.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Phase Ib/II Study of an Anti-HER3 Antibody, HMBD-001, With Cetuximab +/- Docetaxel in Advanced Squamous Cell Cancers [Phase 1, Phase 2]
A Phase Ib/II clinical trial evaluating HMBD-001, an anti-HER3 antibody, in combination with cetuximab with or without docetaxel for advance…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Short-Course Definitive Chemoradiotherapy Combined With Adjuvant or Concurrent Plus Adjuvant Camrelizumab for Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma [Phase 2]
A Phase 2 clinical trial is evaluating short-course definitive chemoradiotherapy with camrelizumab given concurrently or as adjuvant therapy…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Efficacy and Safety of Adebrelimab Combined With Chemoradiotherapy in Patients With Unresectable Locally Advanced or Postoperative Recurrent Esophageal Squamous Cell Carcinoma [Phase 2]
Clinical trial update on the efficacy and safety of Adebrelimab with chemoradiotherapy in patients with unresectable locally advanced or pos…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: First-in-Human Study of PLX-61639 in Locally Advanced or Metastatic Solid Tumors [Phase 1]
Plexium, Inc. is conducting a first-in-human Phase 1 study of PLX-61639 in locally advanced or metastatic solid tumors, and the trial is cur…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas [Phase 1]
Phase 1 study evaluating safety, efficacy, and pharmacokinetics of EVOLVE104 in patients with advanced urothelial cancer and squamous cell c…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors [Phase 2]
Phase 2 study evaluating futibatinib in combination with a PD-1 antibody-based standard of care for locally advanced unresectable or metasta…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Perioperative Toripalimab (JS001) Combined With Neoadjuvant Chemotherapy in Patients With Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma [Phase 3]
Phase 3 trial evaluating perioperative toripalimab in combination with neoadjuvant chemotherapy for patients with resectable locally advance…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Prospective Study of Physical Function in Adults Who Receive Systemic Therapy for Stage I-III Gastroesophageal Cancer, FAST-GO Study
This Clinical Trials update describes the FAST-GO prospective study evaluating physical function in adults receiving systemic therapy for st…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors [Phase 1]
Pfizer's Phase 1 study PF-08046876 is recruiting adults with various advanced solid tumors to evaluate safety and dosing. The trial includes…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer [Phase 3]
A Phase 3 clinical trial comparing proton therapy to photon radiation therapy for esophageal cancer across multiple stages and histologies i…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Observational Study of Patients Treated With Nivolumab and Chemotherapy for Advanced or Metastatic Esophageal, Gastroesophageal or Gastric Cancer in France
An observational study in France evaluating outcomes for patients with advanced gastric and esophageal cancers treated with nivolumab in com…