Diffuse Intrinsic Pontine Glioma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-12-06Clinical Trial Update: Study of Re-irradiation at Relapse Versus RT and Multiple Elective rt Courses [Phase 2]
Phase 2 trial evaluating re-irradiation at relapse versus standard RT and multiple elective RT courses for diffuse intrinsic pontine glioma …
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Nimotuzumab in Combined With Chemoradiotherapy to Treat the Newly Diagnosed Diffuse Intrinsic Pontine Glioma in Children [Phase 3]
A Phase 3 clinical trial evaluating nimotuzumab combined with chemoradiotherapy for newly diagnosed diffuse intrinsic pontine glioma in chil…
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CLINICAL_TRIALS research · 2022-10-20Clinical Trial Update: Diffuse Intrinsic Pontine Glioma (DIPG) Reirradiation (ReRT) [Phase 1, Phase 2]
Phase 1/2 clinical trial update on reirradiation for diffuse intrinsic pontine glioma (DIPG) is completed.
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CLINICAL_TRIALS trial_result · 2022-08-09Clinical Trial Update: Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22 [Phase 1, Phase 2]
Phase 1/2 trial evaluating intraarterial cetuximab (Erbitux) and bevacizumab for relapsed/refractory intracranial glioma in patients under 2…
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CLINICAL_TRIALS trial_result · 2022-06-06Clinical Trial Update: International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013) [Phase 3]
International Phase III trial HIT-HGG-2013 update; no results or status publicly available yet.
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CLINICAL_TRIALS trial_result · 2022-04-12Clinical Trial Update: A Study of DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas [Phase 1, Phase 2]
Phase 1/2 trial of DSP-7888 in pediatric patients with relapsed or refractory high-grade gliomas has completed.
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CLINICAL_TRIALS trial_result · 2022-02-25Clinical Trial Update: MTX110 by Convection-Enhanced Delivery in Treating Participants With Newly-Diagnosed Diffuse Intrinsic Pontine Glioma [Phase 1, Phase 2]
Phase 1/2 clinical trial update for MTX110 delivered via convection-enhanced delivery in newly diagnosed diffuse intrinsic pontine glioma ha…
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CLINICAL_TRIALS trial_result · 2021-08-27Clinical Trial Update: Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors [Phase 1]
Phase 1 trial evaluating ribociclib with everolimus in pediatric patients with recurrent or refractory malignant brain tumors; completed wit…
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CLINICAL_TRIALS trial_result · 2021-07-21Clinical Trial Update: Valproic Acid, Radiation, and Bevacizumab in Children With High Grade Gliomas or Diffuse Intrinsic Pontine Glioma [Phase 2]
Phase 2 trial evaluating valproic acid with radiation and bevacizumab in pediatric high-grade gliomas and diffuse intrinsic pontine glioma h…
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CLINICAL_TRIALS trial_result · 2020-11-05Clinical Trial Update: A Phase I/II Study of Ribociclib,a CDK4/6 Inhibitor, Following Radiation Therapy [Phase 1, Phase 2]
Phase I/II study of ribociclib (CDK4/6 inhibitor) following radiation therapy in high-grade glioma and DIPG was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2020-03-03Clinical Trial Update: Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma [Phase 1, Phase 2]
Phase 1/2 trial evaluating Vorinostat with radiation followed by maintenance therapy in younger patients with newly diagnosed diffuse intrin…
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CLINICAL_TRIALS trial_result · 2019-09-04Clinical Trial Update: Molecularly Determined Treatment of Diffuse Intrinsic Pontine Gliomas (DIPG) [Phase 2]
Phase 2 trial for molecularly determined treatment in diffuse intrinsic pontine glioma (DIPG) has been terminated; results posted in 2019.
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CLINICAL_TRIALS research · 2018-07-23Clinical Trial Update: Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication [Phase 2]
An update on a Phase 2 clinical trial evaluating a biological medicine for Diffuse Intrinsic Pontine Glioma. The current status of the trial…
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CLINICAL_TRIALS trial_result · 2018-05-02Clinical Trial Update: A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas [EARLY_Phase 1]
This early-phase trial evaluated bevacizumab in patients with newly diagnosed high-grade gliomas and diffuse intrinsic pontine glioma; the s…
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CLINICAL_TRIALS research · 2018-03-02Clinical Trial Update: Safety Study of DIPG Treatment With Autologous Dendritic Cells Pulsed With Lysated Allegenic Tumor Lines [Phase 1]
Phase 1 safety study evaluating autologous dendritic cells pulsed with lysed allogeneic tumor lines for Diffuse Intrinsic Pontine Glioma (DI…
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma [Phase 1]
Phase 1 trial of crenolanib, a PDGFR inhibitor, in pediatric patients with Diffuse Intrinsic Pontine Glioma or recurrent high-grade glioma h…
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CLINICAL_TRIALS trial_result · 2016-10-28Clinical Trial Update: Erivedge (Vismodegib) in the Treatment of Pediatric Patients With Refractory Pontine Glioma [Phase 2]
This ClinicalTrials.gov update reports results from a Phase 2 study of vismodegib (Erivedge) in pediatric patients with refractory diffuse i…
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CLINICAL_TRIALS research · 2016-09-13Clinical Trial Update: Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma [Phase 1, Phase 2]
This entry reports a Phase 1/Phase 2 clinical trial evaluating an anti-PD-1 antibody in diffuse intrinsic pontine glioma; no trial results a…
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CLINICAL_TRIALS trial_result · 2016-07-26Clinical Trial Update: DNA Analysis of Tumor Tissue Samples From Patients With Diffuse Brain Stem Glioma
This clinical trial update reports on DNA analysis of tumor tissue samples from patients with diffuse intrinsic pontine glioma, a form of di…
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CLINICAL_TRIALS trial_result · 2015-07-21Clinical Trial Update: Cilengitide and Metronomic Temozolomide for Relapsed or Refractory High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas in Children and Adolescents [Phase 2]
Phase 2 trial in children tested cilengitide with metronomic temozolomide for relapsed or refractory high-grade gliomas and diffuse intrinsi…
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: Palliative Re-irradiation for Progressive Diffuse Intrinsic Pontine Glioma (DIPG) in Children [Phase 1, Phase 2]
A completed phase 1/phase 2 clinical trial evaluated palliative re-irradiation for progressive diffuse intrinsic pontine glioma in children.
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CLINICAL_TRIALS trial_result · 2015-04-06Clinical Trial Update: Clinical Trial Evaluating the Combination of Vandetanib and Dasatinib During and After Radiation Therapy (RT) in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) [Phase 1]
A completed Phase 1 clinical trial evaluating the combination of vandetanib and dasatinib during and after radiation therapy in children wit…
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CLINICAL_TRIALS trial_result · 2014-07-28Clinical Trial Update: Combination Chemotherapy Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma [Phase 1]
This update reports the completion of a Phase 1 trial evaluating a combination of chemotherapy and radiation therapy in children with newly …
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CLINICAL_TRIALS trial_result · 2014-02-21Clinical Trial Update: Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma [Phase 2]
A phase 2 trial evaluating chemotherapy and radiation therapy after surgery in children with newly diagnosed astrocytoma, glioblastoma multi…
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CLINICAL_TRIALS trial_result · 2013-08-12Clinical Trial Update: Temozolomide and Radiation Therapy in Treating Young Patients With Pontine Glioma [Phase 2]
A Phase 2 clinical trial update investigates temozolomide with radiation therapy for young patients with diffuse intrinsic pontine glioma; t…