Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-28Clinical Trial Results: Sildenafil Exercise: Role of PDE5 Inhibition [Phase 2, Phase 3]
Phase 2/3 trial results for sildenafil as a PDE5 inhibitor assessing exercise-related outcomes in cystic fibrosis patients.
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CLINICAL_TRIALS trial_result · 2026-07-16Clinical Trial Results: A Phase 1b/2 Trial of the Safety and Microbiological Activity of Bacteriophage Therapy in Cystic Fibrosis Subjects Colonized With Pseudomonas Aeruginosa [Phase 1, Phase 2]
Phase 1b/2 clinical trial evaluating the safety and microbiological activity of bacteriophage therapy in cystic fibrosis patients colonized …
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CLINICAL_TRIALS trial_result · 2026-06-05Clinical Trial Update: Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age and Older [Phase 3]
A Phase 3 trial update assessing long-term safety and efficacy of ELX/TEZ/IVA (elexacaftor/tezacaftor/ivacaftor) in cystic fibrosis particip…
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CLINICAL_TRIALS trial_result · 2026-04-29Clinical Trial Results: Intrapulmonary Percussive Ventilation for Sputum Induction in Adults With Cystic Fibrosis [NA]
A completed clinical trial evaluating intrapulmonary percussive ventilation for sputum induction in adults with cystic fibrosis; results pos…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Genetic Disorders of Mucociliary Clearance in Nontuberculous Mycobacterial Lung Disease
This completed NHLBI study examined genetic disorders that affect mucociliary clearance in nontuberculous mycobacterial lung disease, includ…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Increase Tolerance for Exercise and Raise Activity Through Connectedness Trial [NA]
A completed clinical trial evaluating increasing exercise tolerance and daily activity through connectedness in individuals with cystic fibr…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Glycerol Phenylbutyrate Corrector Therapy For CF (Cystic Fibrosis) [Phase 1, Phase 2]
Phase 1/2 clinical trial of glycerol phenylbutyrate as a potential cystic fibrosis therapy was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Study to Test How Well BI 3720931 is Tolerated and Whether it Improves Lung Function in People With Cystic Fibrosis (Lenticlair™ 1) [Phase 1, Phase 2]
Boehringer Ingelheim's Lenticlair 1 trial of BI 3720931 in cystic fibrosis has been terminated in Phase 1/2, assessing tolerability and pote…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: An Intervention-Based Approach to Strengthen the Psychological Health of Children With Cystic Fibrosis and Their Mothers [NA]
A completed clinical trial evaluated an intervention-based program, including laughter yoga, to strengthen psychological health in children …
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Bacterial Gene Profiling to Predict Antibiotic Resistance During Cystic Fibrosis Pulmonary Exacerbations
A completed clinical trial from National Jewish Health investigates using bacterial gene profiling to predict antibiotic resistance during c…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Bacteriophages for Adults With Cystic Fibrosis and Chronic Achromobacter Lung Infection [Phase 1]
Phase 1 clinical trial evaluating bacteriophages for adults with cystic fibrosis and chronic Achromobacter xylosoxidans infection. The study…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: DNA Methylation and Lung Disease in Cystic Fibrosis [NA]
This completed clinical trial from University Hospital, Montpellier studied DNA methylation and lung disease in cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Evaluation of the Lung Clearance Index [NA]
A clinical trial update noting the completion of a study evaluating the Lung Clearance Index in cystic fibrosis patients.
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Identification of Predictive Epigenetic Biomarkers of Lung Disease Severity in Cystic Fibrosis [NA]
A completed clinical trial identified epigenetic biomarkers that may predict the severity of lung disease in cystic fibrosis.
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Effect of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) on the PK of Rosuvastatin in Healthy Participants [Phase 1]
A Phase 1 trial evaluated whether Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) alters the pharmacokinetics of rosuvastatin in health…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Ivacaftor in French Patients With Cystic Fibrosis and a G551D Mutation
This clinical trial update reports the completion of a study evaluating Ivacaftor in French patients with cystic fibrosis carrying the G551D…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Natural History of Noncirrhotic Portal Hypertension
This clinical trial update notes that a NIDDK-supported study is investigating the natural history of idiopathic noncirrhotic portal hyperte…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Impact of Bronchial Drainage Technique by the Medical Device Simeox® on Respiratory Function and Symptoms in Adult Patients With Cystic Fibrosis [NA]
A completed clinical trial assessed the effect of the Simeox bronchial drainage device on respiratory function and symptoms in adults with c…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Brensocatib Tablets in Adults With Cystic Fibrosis [Phase 2]
A Phase 2 trial evaluating the safety, tolerability, and pharmacokinetics of Brensocatib tablets in adults with cystic fibrosis has complete…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Validation of Respiratory Epithelial Functional Assessment to Predict Clinical Efficacy of Orkambi®. [NA]
A completed clinical trial update validating a respiratory epithelial functional assay to predict the clinical efficacy of Orkambi in people…
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Older [Phase 3]
Phase 3 long-term safety and efficacy update of elexacaftor/tezacaftor/ivacaftor in cystic fibrosis patients aged 2 years and older; the stu…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: COVID-19 ANtibody Responses in Cystic Fibrosis: CAR-CF
This clinical trial update reports the completion of a study evaluating antibody responses to COVID-19 in people with cystic fibrosis treate…
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: COVID-19 Antibody Responses in Cystic Fibrosis [NA]
A clinical trial update reports on COVID-19 antibody responses in individuals with cystic fibrosis; the study has completed.
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: The Sinonasal Cavity as a Reservoir for Upper Airway Bacterial Development
Completed clinical trial sponsored by the University of Minnesota examining whether the sinonasal cavity acts as a reservoir for upper airwa…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Clean Air for Rare MUcociliary Clearance dIsorders [NA]
This clinical trial update indicates that a study addressing rare mucociliary clearance disorders, including Primary Ciliary Dyskinesia and …