Colorectal Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-28Clinical Trial Results: Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Liver [Phase 2]
Phase 2 trial evaluating hepatic artery infusion pump chemotherapy with floxuridine and dexamethasone plus systemic chemotherapy in patients…
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CLINICAL_TRIALS trial_result · 2026-07-09Clinical Trial Results: A Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 study of pegylated IL-10 (pegilodecakin) in adults with advanced solid tumors; results from a first-in-human trial assessing safety …
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CLINICAL_TRIALS trial_result · 2026-07-08Clinical Trial Results: Phase 1b Dose Escalation Study of Intravenous JX-594 in Metastatic, Refractory Colorectal Carcinoma [Phase 1]
Phase 1b dose-escalation study of intravenous JX-594 in metastatic, refractory colorectal carcinoma completed; results posted.
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: At-Home Cancer Directed Therapy Versus in Clinic for the Treatment of Patients With Advanced Cancer [Phase 2]
A Phase 2 trial sponsored by Mayo Clinic compares at-home cancer-directed therapy to in-clinic treatment for patients with various advanced …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing Obeticholic Acid for Familial Adenomatous Polyposis [Phase 2]
A Phase 2 clinical trial of obeticholic acid for attenuated familial adenomatous polyposis is currently suspended.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial [Phase 1]
This is an early-stage (Phase 1) clinical trial evaluating the combination of DS-8201a (trastuzumab deruxtecan) and AZD6738 (camonsertib) fo…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: The Application of Sentire Surgical System Plus Patient Side Single Arm in Robotic Colorectal Surgery [NA]
Clinical trial update for a single-arm robotic colorectal surgery study using the Sentire Surgical System Plus; status indicates not yet rec…
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: A Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines. [Phase 1]
Phase 1 study of PF-07826390 in cancer patients, including non-small cell lung cancer, was terminated; the trial evaluated different doses o…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Liver Surgery and Chemotherapy in Treating Patients With Colorectal Cancer With Liver Metastases That Can Be Removed by Surgery and Lung Metastases That Cannot Be Removed by Surgery [Phase 2]
A Phase 2 trial evaluated liver surgery plus chemotherapy for colorectal cancer with resectable liver metastases and unresectable lung metas…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Pilot Window of Opportunity Trial (POET) [Phase 2]
This report provides an update on the Phase 2 Pilot Window of Opportunity Trial (POET) led by the University of Oklahoma, currently listed a…
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Immune Checkpoint Inhibitors + Chemotherapy Versus Chemotherapy in the Neoadjuvant Treatment of Locally Advanced Colorectal Cancer [Phase 2]
This Phase 2 trial compares immune checkpoint inhibitors plus chemotherapy versus chemotherapy alone as neoadjuvant treatment for locally ad…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Improving Colonoscopy Surveillance for Patients With High Risk Colon Polyps [NA]
A clinical trial update describing a study to improve colonoscopy surveillance for patients with high-risk colon polyps, currently recruitin…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies [Phase 1]
A Phase 1 study of JANX008 in advanced or metastatic solid tumors is currently recruiting, evaluating multiple indications including Non-Sma…
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors [Phase 1]
Pfizer's PF-07820435 study in advanced solid tumors, including non-small-cell lung cancer and other indications, has been terminated at Phas…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Rectus Sheath Catheters Following Midline Laparotomy [NA]
Clinical trial update on rectus sheath catheters following midline laparotomy; the study is not yet recruiting and sponsored by Asklepios Kl…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: Clinicopathological Value of p16 Expression in Colorectal Carcinoma
A clinical trial update evaluating the clinicopathological value of p16 expression in colorectal carcinoma, sponsored by Sohag University, c…
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CLINICAL_TRIALS withdrawal · 2025-06-05Clinical Trial Update: A Pilot Study to Explore the Role of Gut Flora in Colorectal Cancer
A pilot trial investigating the role of gut microbiota in colorectal cancer has been withdrawn.
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: BXQ-350 in Newly Diagnosed Metastatic Colorectal Carcinoma [Phase 1, Phase 2]
A clinical trial update shows BXQ-350 is being studied in newly diagnosed metastatic colorectal carcinoma in Phase 1/Phase 2. The study is c…
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: The Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Injectable SPN01 in Phase I. [Phase 1]
Phase I trial evaluating the safety, tolerability, pharmacokinetics, and preliminary efficacy of SPN01 injected in colorectal carcinoma; the…
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CLINICAL_TRIALS research · 2024-08-16Clinical Trial Update: A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors [Phase 1]
RemeGen's RC198 is being evaluated in a Phase 1 study across locally advanced unresectable or metastatic solid tumors, including melanoma, u…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 study of PF-07209960 in advanced or metastatic solid tumors was terminated, with results posted in July 2024.
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports results for a combination of liposomal irinotecan, fluorouracil, leucovorin, and rucaparib in pati…
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CLINICAL_TRIALS trial_result · 2024-02-21Clinical Trial Update: Pemigatinib for the Treatment of Metastatic or Unresectable Colorectal Cancer Harboring FGFR Alterations [Phase 2]
Phase 2 clinical trial evaluating pemigatinib for metastatic or unresectable colorectal cancer with FGFR alterations; status and results det…
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CLINICAL_TRIALS trial_result · 2023-08-08Clinical Trial Update: Savolitinib in Treating Patients With MET Amplified Metastatic or Unresectable Colorectal Cancer [Phase 2]
Phase 2 trial investigating savolitinib for MET-amplified metastatic or unresectable colorectal cancer was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: VB-111 in Combination With Nivolumab in People With Metastatic Colorectal Cancer (mCRC) [Phase 2]
Phase 2 trial of VB-111 in combination with nivolumab for metastatic colorectal cancer was terminated, with results posted.