Colorectal Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-01-11Clinical Trial Update: PD-1 Antibody Following Preoperative Chemoradiotherapy for Locally Advanced pMMR/MSS Rectal Cancer [Phase 2]
Phase 2 trial evaluating a PD-1 antibody after preoperative chemoradiotherapy in locally advanced pMMR/MSS rectal cancer.
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CLINICAL_TRIALS trial_result · 2022-11-17Clinical Trial Update: Mechanical Bowel Preparation and Oral Antibiotics Versus Mechanical Bowel Preparation Only Prior Rectal Surgery [Phase 4]
Phase 4 clinical trial evaluating mechanical bowel preparation with oral antibiotics versus mechanical bowel preparation alone prior to rect…
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CLINICAL_TRIALS trial_result · 2021-10-26Clinical Trial Update: Fruquintinib and Raltitrexed Versus Fruquintinib Monotherapy in Advanced Colorectal Cancer [Phase 2]
Phase 2 trial comparing Fruquintinib plus Raltitrexed versus Fruquintinib alone in advanced colorectal carcinoma.
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CLINICAL_TRIALS trial_result · 2021-10-26Clinical Trial Update: A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination With Immune Checkpoint Inhibition in Refractory Colorectal Cancer [Phase 1, Phase 2]
Phase I/II trial investigating Pexa-Vec oncolytic virus in combination with immune checkpoint inhibitor for refractory colorectal cancer has…
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CLINICAL_TRIALS trial_result · 2021-08-19Clinical Trial Update: Safety Study of 90Y-hMN14 to Treat Colorectal Cancer [Phase 1, Phase 2]
Clinical trial update for safety study of 90Y-hMN14 in colorectal cancer (Phase 1/Phase 2) completed.
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CLINICAL_TRIALS trial_result · 2021-06-21Clinical Trial Update: FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status [Phase 2]
A Phase 2 trial evaluating first-line FOLFIRI plus panitumumab in elderly patients with unresectable metastatic colorectal cancer that is RA…
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CLINICAL_TRIALS trial_result · 2021-01-08Clinical Trial Update: Recombinant Vaccinia Virus Administered Intravenously in Patients With Metastatic, Refractory Colorectal Carcinoma [Phase 1, Phase 2]
Phase 1/2 clinical trial investigating intravenously administered recombinant vaccinia virus for metastatic, refractory colorectal carcinoma…
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CLINICAL_TRIALS trial_result · 2020-10-06Clinical Trial Update: Avelumab Plus Autologous Dendritic Cell Vaccine in Pre-treated Metastatic Colorectal Cancer Patients [Phase 1, Phase 2]
Phase 1/2 trial evaluating avelumab with an autologous dendritic cell vaccine in pre-treated metastatic colorectal cancer completed.
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Dolcanatide in Preventing Colorectal Cancer in Healthy Volunteers [Phase 1]
Phase 1 trial evaluating Dolcanatide for preventing colorectal cancer in healthy volunteers has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-11-18Clinical Trial Update: An Evaluation of Tilmanocept by IV Injection Using SPECT/CT vs PET Imaging in Subjects With Liver Metastases. [Phase 1]
Phase 1 trial evaluating tilmanocept via IV injection with SPECT/CT versus PET imaging in subjects with liver metastases; study terminated w…
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CLINICAL_TRIALS trial_result · 2019-07-18Clinical Trial Update: Phase I of SGM-101 in Patients With Cancer of the Colon, Rectum or Pancreas [Phase 1, Phase 2]
Phase I/II clinical trial update for SGM-101 in colon, rectal, and pancreatic cancers, currently completed.
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CLINICAL_TRIALS trial_result · 2019-03-11Clinical Trial Update: BBI608 and Best Supportive Care vs Placebo and Best Supportive Care in Pretreated Advanced Colorectal Carcinoma [Phase 3]
Phase 3 trial comparing BBI608 plus best supportive care against placebo plus best supportive care in pretreated advanced colorectal carcino…
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CLINICAL_TRIALS trial_result · 2019-03-01Clinical Trial Update: Safety and Efficacy Study of mFOLFOX6 + Panitumumab Combination Therapy and 5-FU/LV + Panitumumab Combination Therapy in Participants With Chemotherapy-naïve Unresectable Advanced Recurrent Colorectal Carcinoma [Phase 2]
Phase 2 trial assessing mFOLFOX6 + panitumumab and 5-FU/LV + panitumumab in chemotherapy-naïve unresectable advanced recurrent colorectal ca…
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CLINICAL_TRIALS trial_result · 2018-08-28Clinical Trial Update: Trial Comparing Ferric(III)Carboxymaltose Infusion With Oral Iron Suppletion as Treatment of Anaemia [Phase 4]
Phase 4 trial comparing ferric(III) carboxymaltose infusion with oral iron supplementation for treating anemia in colorectal cancer patients…
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CLINICAL_TRIALS trial_result · 2018-08-16Clinical Trial Update: FOLFIRI and Panitumumab in Treating Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer [Phase 2]
Phase 2 trial updating FOLFIRI plus panitumumab in RAS and BRAF wild-type metastatic colorectal cancer; study terminated with posted results…
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CLINICAL_TRIALS trial_result · 2018-05-29Clinical Trial Update: Colonoscope Passive Bending Function [NA]
This update covers a trial evaluating colonoscope passive bending function; the study is completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: Macrogol 3350-based Oral Osmotic Laxative in Preventing Cancer in Patients at Risk of Colorectal Cancer [Phase 2]
Phase 2 trial evaluating a Macrogol 3350-based oral osmotic laxative for preventing colorectal cancer in patients at risk; the study has com…
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CLINICAL_TRIALS trial_result · 2016-08-25Clinical Trial Update: Phase I FOLFOX Combination [Phase 1]
This update describes a Phase I trial evaluating a FOLFOX chemotherapy combination in advanced colorectal carcinoma, sponsored by Genzyme, w…
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CLINICAL_TRIALS trial_result · 2015-11-06Clinical Trial Update: Accuracy of the Optical Diagnosis of Small Colonic Polyps Using the Nice Classification
A completed study evaluated the accuracy of optical diagnosis of small colonic polyps using the NICE classification, including colorectal ad…
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CLINICAL_TRIALS trial_result · 2014-07-14Clinical Trial Update: SKIP - A Double-blind Placebo-controlled Randomized Multicenter Trial of Skin Toxicity Treatment [Phase 2]
A Phase 2 double-blind, placebo-controlled multicenter trial evaluating a skin toxicity treatment in colorectal carcinoma patients has been …
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CLINICAL_TRIALS trial_result · 2013-04-15Clinical Trial Update: Effect of Sorafenib or Regorafenib on P63 Expression and Keratinocyte Differentiation in Human Skin
A terminated clinical trial evaluated whether Sorafenib or Regorafenib affects P63 expression and keratinocyte differentiation in human skin…
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CLINICAL_TRIALS trial_result · 2012-02-07Clinical Trial Update: Irinotecan, 5-Fluorouracil, and Leucovorin in Colorectal Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating a regimen of irinotecan, 5-fluorouracil, and leucovorin for colorectal carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2008-02-11Clinical Trial Update: Phase 2b Study of VELCADE Alone and VELCADE Plus Irinotecan in Patients With Relapsed or Refractory Colorectal Carcinoma [Phase 2]
A Phase 2b trial evaluating Velcade (bortezomib) alone and in combination with irinotecan for relapsed or refractory colorectal carcinoma ha…