Phase 1/1B Study of DS-8201a in Combination With ATR Inhibition (AZD6738) in Advanced Solid Tumors With HER2 Expression (DASH Trial)

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Record identity and dates

Source

ClinicalTrials.gov

Source record ID

NCT04704661

Title field or adapter rule

protocolSection.identificationModule.officialTitle

Ingested At

2026-04-25T22:27:56.905998+00:00

Published At

2026-04-13T00:00:00+00:00

Record Updated At

2026-04-13

Timestamp Basis

source retrieval time was not retained by the feed adapter

Date limitation

source retrieval time was not retained by the feed adapter

Fields recorded by this source

protocolSection.conditionsModule.conditions

["Advanced Breast Carcinoma", "Advanced Colon Carcinoma", "Advanced Colorectal Carcinoma", "Advanced Endometrial Carcinoma", "Advanced Gastric Carcinoma", "Advanced Gastroesophageal Junction Adenocarcinoma", "Advanced Malignant Solid Neoplasm", "Advanced Salivary Gland Carcinoma", "Anatomic Stage III Breast Cancer AJCC v8", "Anatomic Stage IV Breast Cancer AJCC v8", "Clinical Stage III Gastric Cancer AJCC v8", "Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8", "Clinical Stage IV Gastric Cancer AJCC v8", "Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8", "HER2-Positive Breast Carcinoma", "Malignant Hepatobiliary Neoplasm", "Metastatic Breast Carcinoma", "Metastatic Colon Carcinoma", "Metastatic Colorectal Carcinoma", "Metastatic Endometrial Carcinoma", "Metastatic Gastric Carcinoma", "Metastatic Gastroesophageal Junction Adenocarcinoma", "Metastatic Malignant Solid Neoplasm", "Metastatic Salivary Gland Carcinoma", "Stage III Colon Cancer AJCC v8", "Stage III Colorectal Cancer AJCC v8", "Stage III Major Salivary Gland Cancer AJCC v8", "Stage III Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8", "Stage IV Colon Cancer AJCC v8", "Stage IV Colorectal Cancer AJCC v8", "Stage IV Major Salivary Gland Cancer AJCC v8", "Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8", "Unresectable Breast Carcinoma", "Unresectable Colon Carcinoma", "Unresectable Colorectal Carcinoma", "Unresectable Endometrial Carcinoma", "Unresectable Gastric Carcinoma", "Unresectable Gastroesophageal Junction Adenocarcinoma", "Unresectable Malignant Solid Neoplasm", "Unresectable Salivary Gland Carcinoma"]

protocolSection.statusModule.lastUpdatePostDateStruct.date

"2026-04-13"

protocolSection.identificationModule.nctId

"NCT04704661"

protocolSection.identificationModule.officialTitle

"Phase 1/1B Study of DS-8201a in Combination With ATR Inhibition (AZD6738) in Advanced Solid Tumors With HER2 Expression (DASH Trial)"

protocolSection.statusModule.overallStatus

"RECRUITING"

protocolSection.designModule.phases

["PHASE1"]

protocolSection.statusModule.resultsFirstPostDateStruct.date

""

Study condition terms

• Advanced Breast Carcinoma (protocolSection.conditionsModule.conditions)
• Advanced Colon Carcinoma (protocolSection.conditionsModule.conditions)
• Advanced Colorectal Carcinoma (protocolSection.conditionsModule.conditions)
• Advanced Endometrial Carcinoma (protocolSection.conditionsModule.conditions)
• Advanced Gastric Carcinoma (protocolSection.conditionsModule.conditions)
• Advanced Gastroesophageal Junction Adenocarcinoma (protocolSection.conditionsModule.conditions)
• Advanced Malignant Solid Neoplasm (protocolSection.conditionsModule.conditions)
• Advanced Salivary Gland Carcinoma (protocolSection.conditionsModule.conditions)
• Anatomic Stage III Breast Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Anatomic Stage IV Breast Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Clinical Stage III Gastric Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Clinical Stage IV Gastric Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 (protocolSection.conditionsModule.conditions)
• HER2-Positive Breast Carcinoma (protocolSection.conditionsModule.conditions)
• Malignant Hepatobiliary Neoplasm (protocolSection.conditionsModule.conditions)
• Metastatic Breast Carcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Colon Carcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Colorectal Carcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Endometrial Carcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Gastric Carcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Gastroesophageal Junction Adenocarcinoma (protocolSection.conditionsModule.conditions)
• Metastatic Malignant Solid Neoplasm (protocolSection.conditionsModule.conditions)
• Metastatic Salivary Gland Carcinoma (protocolSection.conditionsModule.conditions)
• Stage III Colon Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage III Colorectal Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage III Major Salivary Gland Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage III Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage IV Colon Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage IV Colorectal Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage IV Major Salivary Gland Cancer AJCC v8 (protocolSection.conditionsModule.conditions)
• Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8 (protocolSection.conditionsModule.conditions)
• Unresectable Breast Carcinoma (protocolSection.conditionsModule.conditions)
• Unresectable Colon Carcinoma (protocolSection.conditionsModule.conditions)
• Unresectable Colorectal Carcinoma (protocolSection.conditionsModule.conditions)
• Unresectable Endometrial Carcinoma (protocolSection.conditionsModule.conditions)
• Unresectable Gastric Carcinoma (protocolSection.conditionsModule.conditions)
• Unresectable Gastroesophageal Junction Adenocarcinoma (protocolSection.conditionsModule.conditions)
• Unresectable Malignant Solid Neoplasm (protocolSection.conditionsModule.conditions)
• Unresectable Salivary Gland Carcinoma (protocolSection.conditionsModule.conditions)

Intervention details are not present in the imported fields for this record. No drug-condition relationship is inferred from co-listing.

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