Colorectal Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-28Clinical Trial Results: Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Liver [Phase 2]
Phase 2 trial evaluating hepatic artery infusion pump chemotherapy with floxuridine and dexamethasone plus systemic chemotherapy in patients…
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CLINICAL_TRIALS trial_result · 2026-07-09Clinical Trial Results: A Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 study of pegylated IL-10 (pegilodecakin) in adults with advanced solid tumors; results from a first-in-human trial assessing safety …
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CLINICAL_TRIALS trial_result · 2026-07-08Clinical Trial Results: Phase 1b Dose Escalation Study of Intravenous JX-594 in Metastatic, Refractory Colorectal Carcinoma [Phase 1]
Phase 1b dose-escalation study of intravenous JX-594 in metastatic, refractory colorectal carcinoma completed; results posted.
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: A Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines. [Phase 1]
Phase 1 study of PF-07826390 in cancer patients, including non-small cell lung cancer, was terminated; the trial evaluated different doses o…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Liver Surgery and Chemotherapy in Treating Patients With Colorectal Cancer With Liver Metastases That Can Be Removed by Surgery and Lung Metastases That Cannot Be Removed by Surgery [Phase 2]
A Phase 2 trial evaluated liver surgery plus chemotherapy for colorectal cancer with resectable liver metastases and unresectable lung metas…
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors [Phase 1]
Pfizer's PF-07820435 study in advanced solid tumors, including non-small-cell lung cancer and other indications, has been terminated at Phas…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Study to Test the Safety and Tolerability of PF-07209960 in Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 study of PF-07209960 in advanced or metastatic solid tumors was terminated, with results posted in July 2024.
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Liposomal Irinotecan, Fluorouracil, Leucovorin Calcium, and Rucaparib in Treating Patients With Metastatic Pancreatic, Colorectal, Gastroesophageal, or Biliary Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports results for a combination of liposomal irinotecan, fluorouracil, leucovorin, and rucaparib in pati…
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CLINICAL_TRIALS trial_result · 2024-02-21Clinical Trial Update: Pemigatinib for the Treatment of Metastatic or Unresectable Colorectal Cancer Harboring FGFR Alterations [Phase 2]
Phase 2 clinical trial evaluating pemigatinib for metastatic or unresectable colorectal cancer with FGFR alterations; status and results det…
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CLINICAL_TRIALS trial_result · 2023-08-08Clinical Trial Update: Savolitinib in Treating Patients With MET Amplified Metastatic or Unresectable Colorectal Cancer [Phase 2]
Phase 2 trial investigating savolitinib for MET-amplified metastatic or unresectable colorectal cancer was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: VB-111 in Combination With Nivolumab in People With Metastatic Colorectal Cancer (mCRC) [Phase 2]
Phase 2 trial of VB-111 in combination with nivolumab for metastatic colorectal cancer was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2023-01-11Clinical Trial Update: PD-1 Antibody Following Preoperative Chemoradiotherapy for Locally Advanced pMMR/MSS Rectal Cancer [Phase 2]
Phase 2 trial evaluating a PD-1 antibody after preoperative chemoradiotherapy in locally advanced pMMR/MSS rectal cancer.
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CLINICAL_TRIALS trial_result · 2022-11-17Clinical Trial Update: Mechanical Bowel Preparation and Oral Antibiotics Versus Mechanical Bowel Preparation Only Prior Rectal Surgery [Phase 4]
Phase 4 clinical trial evaluating mechanical bowel preparation with oral antibiotics versus mechanical bowel preparation alone prior to rect…
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CLINICAL_TRIALS trial_result · 2021-10-26Clinical Trial Update: Fruquintinib and Raltitrexed Versus Fruquintinib Monotherapy in Advanced Colorectal Cancer [Phase 2]
Phase 2 trial comparing Fruquintinib plus Raltitrexed versus Fruquintinib alone in advanced colorectal carcinoma.
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CLINICAL_TRIALS trial_result · 2021-10-26Clinical Trial Update: A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination With Immune Checkpoint Inhibition in Refractory Colorectal Cancer [Phase 1, Phase 2]
Phase I/II trial investigating Pexa-Vec oncolytic virus in combination with immune checkpoint inhibitor for refractory colorectal cancer has…
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CLINICAL_TRIALS trial_result · 2021-08-19Clinical Trial Update: Safety Study of 90Y-hMN14 to Treat Colorectal Cancer [Phase 1, Phase 2]
Clinical trial update for safety study of 90Y-hMN14 in colorectal cancer (Phase 1/Phase 2) completed.
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CLINICAL_TRIALS trial_result · 2021-06-21Clinical Trial Update: FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status [Phase 2]
A Phase 2 trial evaluating first-line FOLFIRI plus panitumumab in elderly patients with unresectable metastatic colorectal cancer that is RA…
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CLINICAL_TRIALS trial_result · 2021-01-08Clinical Trial Update: Recombinant Vaccinia Virus Administered Intravenously in Patients With Metastatic, Refractory Colorectal Carcinoma [Phase 1, Phase 2]
Phase 1/2 clinical trial investigating intravenously administered recombinant vaccinia virus for metastatic, refractory colorectal carcinoma…
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CLINICAL_TRIALS trial_result · 2020-10-06Clinical Trial Update: Avelumab Plus Autologous Dendritic Cell Vaccine in Pre-treated Metastatic Colorectal Cancer Patients [Phase 1, Phase 2]
Phase 1/2 trial evaluating avelumab with an autologous dendritic cell vaccine in pre-treated metastatic colorectal cancer completed.
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Dolcanatide in Preventing Colorectal Cancer in Healthy Volunteers [Phase 1]
Phase 1 trial evaluating Dolcanatide for preventing colorectal cancer in healthy volunteers has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-11-18Clinical Trial Update: An Evaluation of Tilmanocept by IV Injection Using SPECT/CT vs PET Imaging in Subjects With Liver Metastases. [Phase 1]
Phase 1 trial evaluating tilmanocept via IV injection with SPECT/CT versus PET imaging in subjects with liver metastases; study terminated w…
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CLINICAL_TRIALS trial_result · 2019-07-18Clinical Trial Update: Phase I of SGM-101 in Patients With Cancer of the Colon, Rectum or Pancreas [Phase 1, Phase 2]
Phase I/II clinical trial update for SGM-101 in colon, rectal, and pancreatic cancers, currently completed.
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CLINICAL_TRIALS trial_result · 2019-03-11Clinical Trial Update: BBI608 and Best Supportive Care vs Placebo and Best Supportive Care in Pretreated Advanced Colorectal Carcinoma [Phase 3]
Phase 3 trial comparing BBI608 plus best supportive care against placebo plus best supportive care in pretreated advanced colorectal carcino…
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CLINICAL_TRIALS trial_result · 2019-03-01Clinical Trial Update: Safety and Efficacy Study of mFOLFOX6 + Panitumumab Combination Therapy and 5-FU/LV + Panitumumab Combination Therapy in Participants With Chemotherapy-naïve Unresectable Advanced Recurrent Colorectal Carcinoma [Phase 2]
Phase 2 trial assessing mFOLFOX6 + panitumumab and 5-FU/LV + panitumumab in chemotherapy-naïve unresectable advanced recurrent colorectal ca…
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CLINICAL_TRIALS trial_result · 2018-08-28Clinical Trial Update: Trial Comparing Ferric(III)Carboxymaltose Infusion With Oral Iron Suppletion as Treatment of Anaemia [Phase 4]
Phase 4 trial comparing ferric(III) carboxymaltose infusion with oral iron supplementation for treating anemia in colorectal cancer patients…