Clear Cell Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: RP2 and Tivozanib for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy [Phase 2]
A Phase 2 clinical trial update evaluating RP2 in combination with tivozanib for metastatic renal cell carcinoma after progression on immuno…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A Study to Assess Safety, Tolerability and Imaging Characteristics of [68Ga]Ga-DPI-4452 and to Assess Safety, Tolerability, and Efficacy of [177Lu]Lu-DPI-4452 in Participants With Unresectable Locally Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial update describing safety, tolerability, and imaging with [68Ga]Ga-DPI-4452 and safety, tolerability, and efficacy…
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: Study of ARO-HIF2 in Patients With Advanced Clear Cell Renal Cell Carcinoma [Phase 1]
The document is a Clinical Trial Update reporting a Phase 1 study of ARO-HIF2 in advanced clear cell renal cell carcinoma, with the trial st…
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CLINICAL_TRIALS other · 2025-10-09Clinical Trial Update: A Study of Subcutaneous Nivolumab Versus Intravenous Nivolumab in Participants With Previously Treated Clear Cell Renal Cell Carcinoma That is Advanced or Has Spread [Phase 3]
Phase 3 trial comparing subcutaneous versus intravenous nivolumab in previously treated advanced or metastatic clear cell renal cell carcino…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Phase I Study of Allogeneic Transforming Growth Factor-beta Receptor Type 2 Knockout CD70 CAR NK Cells in Treatment Refractory Clear Cell Renal Cell Carcinoma [Phase 1]
An ongoing Phase I study at MD Anderson tests allogeneic CD70 CAR NK cells engineered with TGF-beta receptor type 2 knockout for treatment-r…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Prior Axitinib as a Determinant of Outcome of Renal Surgery [Phase 2]
Phase 2 clinical trial evaluating whether prior axitinib affects surgical outcomes in clear cell renal cell carcinoma; the study is currentl…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Neoadjuvant Study With Combination Immuno-oncology for Primary Clear Cell Renal Cell Cancer [Phase 2]
Phase 2 neoadjuvant immuno-oncology trial for primary clear cell renal cell carcinoma. The study is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Safety and Efficacy of ALLO-316 in Subjects With Advanced or Metastatic Clear Cell Renal Cell Carcinoma [Phase 1]
A Phase 1 clinical trial update on ALLO-316 for advanced or metastatic clear cell renal cell carcinoma, noting safety and efficacy assessmen…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Modulation of the Bone Immune Microenvironment Following Cabozantinib Treatment of Bone Metastatic Clear Cell Renal Cell Carcinoma: Proof of Concept Study [Phase 1]
Phase 1 clinical trial update evaluating cabozantinib's effects on the bone immune microenvironment in bone-metastatic clear cell renal cell…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Adding a Live Biotherapeutic Product (CBM588) to Pembrolizumab for the Treatment of Renal Cell Cancer After Surgery [Phase 2]
Phase 2 trial exploring adding CBM588 to pembrolizumab for renal cell carcinoma after surgery; the study status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit [Phase 1]
Phase 1 study evaluating NN3201, a c-Kit targeted antibody-drug conjugate, in advanced and/or metastatic solid tumors expressing c-Kit; curr…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: AB-2100, an Integrated Circuit T Cell Therapy in Patients With Recurrent Clear-cell Renal Cell Carcinoma (ccRCC) [Phase 1, Phase 2]
Arsenal Biosciences reports an ongoing Phase 1/2 clinical trial of AB-2100, an integrated circuit T cell therapy, in patients with recurrent…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Real-World Effectiveness and Pharmacogenetics of Belzutifan in VHL Syndrome: The BELIEVE-VHL Trial [Phase 2]
Phase 2 BELIEVE-VHL trial is assessing real-world effectiveness and pharmacogenetics of belzutifan in Von Hippel-Lindau syndrome; recruitmen…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial [Phase 3]
The PROBE trial is a Phase 3 study evaluating immunotherapy-based combination therapy for metastatic renal cell carcinoma with or without su…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial [Phase 1, Phase 2]
Clinical trial update describing the ICON study, evaluating a combination of an inulin gel with ipilimumab and nivolumab for locally advance…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Multiomics Approach in Metastatic Clear Renal Cell Carcnoma
This clinical trial update describes a study using a multiomics approach for metastatic clear cell renal cell carcinoma, with the trial curr…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: KSD-201 Treatment for Advanced Clear Cell Renal Cell Carcinoma: an Early Exploratory Clinical Study [EARLY_Phase 1]
An early exploratory Phase 1 study evaluating KSD-201 for advanced clear cell renal cell carcinoma; currently not yet recruiting.
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CLINICAL_TRIALS withdrawal · 2025-08-19Clinical Trial Update: PSMA Therapy and Immunotherapy in Kidney Cancer [Phase 1, Phase 2]
A clinical trial investigating PSMA-targeted therapy and immunotherapy for metastatic renal cell carcinoma has been withdrawn.
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CLINICAL_TRIALS other · 2025-08-15Clinical Trial Update: A Phase 1/2 Trial of ADI-270 in ccRCC [Phase 1, Phase 2]
This is an update on the Phase 1/2 trial of ADI-270 for clear cell renal cell carcinoma; the study is currently active but not recruiting.
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CLINICAL_TRIALS other · 2025-08-14Clinical Trial Update: A Study of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022) [Phase 3]
A Phase 3 trial evaluating belzutifan plus pembrolizumab versus placebo plus pembrolizumab in post-nephrectomy clear cell renal cell carcino…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: 68Ga-NYM096 PET/ CT for the Detection of Clear Cell Renal Cell Carcinoma in Presurgical Patients With Renal Masses [Phase 2]
A Phase 2 clinical trial update for the PET radiotracer 68Ga-NYM096 aiming to detect clear cell renal cell carcinoma in presurgical patients…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors [Phase 1]
Phase 1, first-in-human dose-finding and expansion study of XmAb808 in combination with pembrolizumab in advanced solid tumors; the trial ha…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Study of HS-10516 Combination Therapy in Patients With Advanced Renal Cell Carcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating HS-10516 combination therapy in patients with advanced renal cell carcinoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: ABEMA Alone or in COMBO With MK-6482 [Phase 1]
Phase 1 study evaluating ABEMA (abemaciclib) alone or in combination with MK-6482 (belzutifan) in patients with Clear cell renal cell carcin…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Clinical Evaluation of [68Ga]Ga-XT771 PET for Diagnosis in Patients With Glioblastoma and Clear Cell Renal Cell Carcinoma [EARLY_Phase 1]
Early-phase clinical trial evaluating the diagnostic PET tracer [68Ga]Ga-XT771 for glioblastoma and clear cell renal cell carcinoma, current…