Clear Cell Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Testing AZD1775 in Advanced Solid Tumors That Have a Mutation Called SETD2 [Phase 2]
An ongoing Phase 2 trial evaluating the WEE1 inhibitor adavosertib (AZD1775) in advanced solid tumors with SETD2 mutations, including clear …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Dual-target CD70/CAIX CAR-NK Cells for Advanced Clear Cell Renal Cell Carcinoma [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating dual-target CD70/CAIX CAR-NK cells for advanced or metastatic clear cell renal cell carcinoma is curre…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Phase I/II Study Evaluating PSMA Targeted Radionuclide Therapy in Adult Patients With Metastatic Clear Cell Renal Cancer [Phase 1, Phase 2]
Phase I/II study evaluating PSMA-targeted radionuclide therapy in adults with metastatic clear cell renal cell carcinoma has completed its P…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors [Phase 2]
Phase 2 clinical trial update of ceralasertib (AZD6738) alone and in combination with olaparib or durvalumab in various solid tumors; the st…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Cadonilimab Combination With Lenvatinib as Neoadjuvant Therapy for ccRCC [Phase 2]
A Phase 2 trial evaluating cadonilimab in combination with lenvatinib as neoadjuvant therapy for clear cell renal cell carcinoma has complet…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Perioperative Lenvatinib With Pembrolizumab in Patients With Locally Advanced Nonmetastatic Clear Cell Renal Cell Carcinoma [Phase 2]
Phase 2 trial examining perioperative lenvatinib with pembrolizumab in locally advanced nonmetastatic clear cell renal cell carcinoma; resul…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: CAIX PET/ CT Guided Radiation Therapy in CcRCC. [NA]
This entry reports an ongoing clinical trial evaluating CAIX PET/CT-guided radiation therapy for clear cell renal cell carcinoma, including …
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Phase 1b/2 Study of Combination 177Lu Girentuximab Plus Cabozantinib and Nivolumab in Treatment naïve Patients With Advanced Clear Cell RCC [Phase 1, Phase 2]
Phase 1b/2 trial evaluating a triple combination of 177Lu-girentuximab, cabozantinib, and nivolumab in treatment-naïve patients with advance…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Study of Combination Spartalizumab and Canakinumab in Patients With Localized Clear Cell Renal Cell Carcinoma [EARLY_Phase 1]
An early-phase 1 study evaluating the combination of Spartalizumab and Canakinumab in localized clear cell renal cell carcinoma has complete…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Nivolumab and Ipilimumab With and Without Camu Camu for the Treatment of Patients With Metastatic Renal Cell Carcinoma [Phase 1]
Phase 1 clinical trial evaluating nivolumab and ipilimumab with and without Camu Camu in metastatic renal cell carcinoma, including clear ce…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: IB-T101 Injection for Treatment of Patients With Advanced Clear Cell Renal Cell Carcinoma [Phase 1]
Phase 1 clinical trial evaluating IB-T101 injection for advanced clear cell renal cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors [Phase 1]
KO-2806 is being studied in Phase 1 trials as a monotherapy and in combination regimens for advanced solid tumors, including HRAS-altered ca…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study [Phase 3]
PDIGREE is a Phase 3 trial evaluating nivolumab plus ipilimumab followed by nivolumab with or without cabozantinib in advanced renal cell ca…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study [Phase 2]
Phase 2 trial exploring the addition of radium-223 dichloride to cabozantinib for advanced renal cell carcinoma with bone metastases (RadiCa…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Safety and Feasibility of Immunotherapy Drugs, Botensilimab and Balstilimab, Before Surgery for Clear Cell Renal Cell Carcinoma, NEO RoBOT Trial [Phase 2]
This update describes a Phase 2 trial to assess the safety and feasibility of Botensilimab and Balstilimab given before surgery for clear ce…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Palbociclib and Sasanlimab for the Treatment of Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Papillary Renal Cell Carcinoma (pRCC) [Phase 1, Phase 2]
A sponsor-backed Phase 1/2 clinical trial evaluates the combination of palbociclib and sasanlimab for advanced clear cell renal cell carcino…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer [Phase 3]
Phase 3 trial evaluating adding tivozanib to pembrolizumab after surgery for kidney cancer; currently recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC) [Phase 1]
A first-in-human Phase 1 trial evaluating BMS-986506 in adults with advanced clear cell renal cell carcinoma (ccRCC); recruitment is ongoing…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Neoadjuvant Zanzalintinib Plus Nivolumab in Patients With Locally Advanced and/or Inoperable Clear Cell Renal Cell Carcinoma With or Without Non-measurable Metastasis [Phase 2]
A Phase 2 neoadjuvant trial evaluating Zanzalintinib plus nivolumab for locally advanced or inoperable clear cell renal cell carcinoma (with…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Trial of Zanzalintinib (XL092) in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC [Phase 2]
This is a Phase 2 clinical trial update for Zanzalintinib (XL092) in combination with immunotherapy for advanced or metastatic renal cell ca…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: VSV-IFNβ-NIS With Ipilimumab and Nivolumab for the Treatment of Advanced or Metastatic Clear Cell Renal Cell Carcinoma [Phase 2]
A Phase 2 trial evaluating VSV-IFNβ-NIS in combination with ipilimumab and nivolumab for advanced or metastatic clear cell renal cell carcin…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Randomized Trial of Fianlimab and Cemiplimab +/- Ipilimumab or Ipilimumab Plus Nivolumab in First-line Advanced Renal Cell Carcinoma (RCC) [Phase 2]
A Phase 2 randomized trial evaluating the combination of fianlimab and cemiplimab with or without ipilimumab, or ipilimumab plus nivolumab, …
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Phase 3 Study to Assess Safety and Efficacy of 177Lu-TLX250 in Advanced Relapsed or Recurrent ccRCC [Phase 3]
Phase 3 study to assess safety and efficacy of 177Lu-TLX250 in advanced relapsed or recurrent clear cell renal cell carcinoma is currently r…
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CLINICAL_TRIALS other · 2026-04-01Clinical Trial Update: Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma [Phase 3]
A Phase 3 clinical trial comparing Casdatifan plus cabozantinib versus placebo plus cabozantinib in patients with advanced or metastatic cle…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders
An NCI-sponsored clinical trial evaluating Von Hippel-Lindau–associated renal and other urologic malignancies, including manifestations, dia…