Clear Cell Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Phase I/II Study Evaluating PSMA Targeted Radionuclide Therapy in Adult Patients With Metastatic Clear Cell Renal Cancer [Phase 1, Phase 2]
Phase I/II study evaluating PSMA-targeted radionuclide therapy in adults with metastatic clear cell renal cell carcinoma has completed its P…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Cadonilimab Combination With Lenvatinib as Neoadjuvant Therapy for ccRCC [Phase 2]
A Phase 2 trial evaluating cadonilimab in combination with lenvatinib as neoadjuvant therapy for clear cell renal cell carcinoma has complet…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Perioperative Lenvatinib With Pembrolizumab in Patients With Locally Advanced Nonmetastatic Clear Cell Renal Cell Carcinoma [Phase 2]
Phase 2 trial examining perioperative lenvatinib with pembrolizumab in locally advanced nonmetastatic clear cell renal cell carcinoma; resul…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Study of Combination Spartalizumab and Canakinumab in Patients With Localized Clear Cell Renal Cell Carcinoma [EARLY_Phase 1]
An early-phase 1 study evaluating the combination of Spartalizumab and Canakinumab in localized clear cell renal cell carcinoma has complete…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Study of Adaptive Immunotherapy With VEGFR-TKI in Patients With Advanced RCC [Phase 2]
A Phase 2 study evaluating adaptive immunotherapy with a VEGFR-TKI in patients with advanced renal cell carcinoma has been suspended.
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Real World Evidence of Tivozanib as First-line Treatment for Metastatic Clear Cell Renal Cell Carcinoma
This completed study reports real-world evidence on using tivozanib as first-line therapy for metastatic clear cell renal cell carcinoma.
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: A Study to Evaluate the Safety and Dosimetry of 68Ga-OncoCAIX in Patients With CAIX-positive Cancer [Phase 1]
A Phase 1 study evaluating safety and dosimetry of the radiotracer 68Ga-OncoCAIX in CAIX-positive cancer has completed, including patients w…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Nivolumab With or Without Bevacizumab or Ipilimumab Before Surgery in Treating Patients With Metastatic Kidney Cancer That Can Be Removed by Surgery [EARLY_Phase 1]
An early-phase trial evaluating nivolumab with or without bevacizumab or ipilimumab before surgery in patients with resectable metastatic re…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: 68Ga-NYM096/177Lu-NYM096 in Metastatic ccRCC [Phase 1]
A Phase 1 trial of 68Ga-NYM096 and 177Lu-NYM096 for metastatic clear cell renal cell carcinoma is currently suspended.
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Aldesleukin and Pembrolizumab in Treating Patients With Advanced or Metastatic Kidney Cancer [Phase 1]
Phase 1 study of aldesleukin in combination with pembrolizumab in advanced or metastatic renal cell carcinoma has been terminated with resul…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Basket Trial Exploring the Efficacy and Safety of the Combination of Niraparib and Dostarlimab [Phase 2]
A Phase 2 basket trial evaluating the combination of niraparib and dostarlimab across multiple cancers has been terminated.
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors [Phase 1, Phase 2]
Clinical trial update reports the completion of a Phase 1/2 safety and efficacy study of CTX131 in adults with relapsed or refractory solid …
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Study of BDC-3042 as Single Agent and in Combination With Cemiplimab in Patients With Advanced Malignancies [Phase 1]
This clinical trial update notes the termination of a Phase 1 study of BDC-3042 as a single agent and in combination with cemiplimab in pati…
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Ph2 Study NKT2152 With Palbociclib & Sasanlimab in Subjects With Advanced Clear Cell Renal Cell Carcinoma (ccRcc) [Phase 2]
Phase 2 study evaluating NKT2152 in combination with palbociclib and sasanlimab for advanced clear cell renal cell carcinoma has been termin…
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors [Phase 1]
This is a completed Phase 1 clinical trial update evaluating CHS-388 (formerly SRF388) in patients with advanced solid tumors, including cle…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors [Phase 1, Phase 2]
A clinical trial update on REGN5678 (Nezastomig) alone or in combination with cemiplimab to treat metastatic castration-resistant prostate c…
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: Pembrolizumab With or Without Axitinib for Clear Cell Kidney Cancer in Patients Undergoing Surgery [Phase 2]
A Phase 2 trial evaluating pembrolizumab with or without axitinib for clear cell renal cell carcinoma in patients undergoing surgery was ter…
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: Study of ARO-HIF2 in Patients With Advanced Clear Cell Renal Cell Carcinoma [Phase 1]
The document is a Clinical Trial Update reporting a Phase 1 study of ARO-HIF2 in advanced clear cell renal cell carcinoma, with the trial st…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Safety and Efficacy of ALLO-316 in Subjects With Advanced or Metastatic Clear Cell Renal Cell Carcinoma [Phase 1]
A Phase 1 clinical trial update on ALLO-316 for advanced or metastatic clear cell renal cell carcinoma, noting safety and efficacy assessmen…
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CLINICAL_TRIALS trial_result · 2025-08-08Clinical Trial Update: 68Ga-NYM096 PET/ CT for the Detection of Clear Cell Renal Cell Carcinoma in Presurgical Patients With Renal Masses [Phase 2]
A Phase 2 clinical trial update for the PET radiotracer 68Ga-NYM096 aiming to detect clear cell renal cell carcinoma in presurgical patients…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors [Phase 1]
Phase 1, first-in-human dose-finding and expansion study of XmAb808 in combination with pembrolizumab in advanced solid tumors; the trial ha…
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: ABEMA Alone or in COMBO With MK-6482 [Phase 1]
Phase 1 study evaluating ABEMA (abemaciclib) alone or in combination with MK-6482 (belzutifan) in patients with Clear cell renal cell carcin…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: A Trial of Belzutifan (PT2977, MK-6482) Tablets In Patients With Advanced Solid Tumors (MK-6482-001) [Phase 1]
Phase 1 trial update of belzutifan (PT2977, MK-6482) in patients with advanced solid tumors; study status is Phase 1 and not recruiting.
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: AURORAX-0087A: GAG Scores for Surveillance of Recurrence in Leibovich Points ≥5 Non-metastatic ccRCC
This clinical trial update reports on AURORAX-0087A, a study evaluating glycosaminoglycan (GAG) scores for surveillance of recurrence in non…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Study of Zanzalintinib (XL092) + AB521 and Zanzalintinib + AB521 + Nivolumab in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Other Advanced Solid Tumors (STELLAR-009) [Phase 1]
Phase 1 study evaluating Zanzalintinib (XL092) in combination with AB521, and Zanzalintinib with AB521 plus Nivolumab, in participants with …