Clear Cell Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Study of Nivolumab in Combination With 177Lu-girentuximab for Kidney Cancer [Phase 2]
Phase 2 trial evaluating nivolumab in combination with 177Lu-girentuximab for renal cell carcinoma is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: A Study to Evaluate the Safety and Dosimetry of 68Ga-OncoCAIX in Patients With CAIX-positive Cancer [Phase 1]
A Phase 1 study evaluating safety and dosimetry of the radiotracer 68Ga-OncoCAIX in CAIX-positive cancer has completed, including patients w…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Nivolumab With or Without Bevacizumab or Ipilimumab Before Surgery in Treating Patients With Metastatic Kidney Cancer That Can Be Removed by Surgery [EARLY_Phase 1]
An early-phase trial evaluating nivolumab with or without bevacizumab or ipilimumab before surgery in patients with resectable metastatic re…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Phase II Trial of Single Agent Belzutifan or Pembrolizumab Versus Combination as Neoadjuvant Therapy in Clear Cell Renal Cell Carcinoma (BLAZE) [Phase 2]
Phase II neoadjuvant trial in clear cell renal cell carcinoma comparing single-agent belzutifan or pembrolizumab versus their combination. T…
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: 68Ga-NYM096/177Lu-NYM096 in Metastatic ccRCC [Phase 1]
A Phase 1 trial of 68Ga-NYM096 and 177Lu-NYM096 for metastatic clear cell renal cell carcinoma is currently suspended.
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Identification of Novel High Quality Methylated DNA Markers in Renal Tumors: Whole Methylome Discovery, Tissue Validation, and Feasibility Testing In Blood and Urine, The INQUIRE Study
A Mayo Clinic-led INQUIRE study is identifying novel high-quality methylated DNA markers for renal tumors. The project uses whole-methylome …
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Axitinib With or Without Anti-OX40 Antibody PF-04518600 in Treating Patients With Metastatic Kidney Cancer [Phase 2]
Phase 2 trial evaluating axitinib with or without the anti-OX40 antibody PF-04518600 for metastatic renal cell carcinoma, currently active a…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: A First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their Body [Phase 1, Phase 2]
First-in-human Phase 1/2 trial evaluating REGN10597 alone or with cemiplimab in adults with melanoma, clear-cell renal cell carcinoma, and o…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Iparomlimab and Tuvonralimab Injection in Combination With Lenvatinib or Axitinib for the Treatment of Locally Advanced or Metastatic Clear Cell Renal Cell Carcinoma That Has Failed First-Line Systemic Therapy [Phase 2]
Phase 2 clinical trial update evaluating iparomlimab and tuvonralimab in combination with lenvatinib or axitinib for locally advanced or met…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Seleno-L Methionine (SLM)-Axitinib-Pembrolizumab [Phase 1, Phase 2]
Phase 1/2 trial of Seleno-L Methionine with Axitinib and Pembrolizumab for clear cell renal cell carcinoma, including metastatic disease, is…
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CLINICAL_TRIALS withdrawal · 2025-12-10Clinical Trial Update: Piflufolastat F 18 PET/CT in Patients With Suspected, or at High Risk for Metastatic ccRCC [Phase 2, Phase 3]
A Phase 2/3 trial evaluating Pylarify (piflufolastat F-18) PET/CT for suspected or high-risk metastatic clear cell renal cell carcinoma has …
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Aldesleukin and Pembrolizumab in Treating Patients With Advanced or Metastatic Kidney Cancer [Phase 1]
Phase 1 study of aldesleukin in combination with pembrolizumab in advanced or metastatic renal cell carcinoma has been terminated with resul…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: [18F]PT2385 PET/CT in Patients With Renal Cell Carcinoma [Phase 1]
Phase 1 clinical trial evaluating [18F]PT2385 PET/CT in renal cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors [Phase 2]
This Phase 2 clinical trial update reports recruitment for an alternative cabozantinib dosing schedule in metastatic renal cell carcinoma an…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Basket Trial Exploring the Efficacy and Safety of the Combination of Niraparib and Dostarlimab [Phase 2]
A Phase 2 basket trial evaluating the combination of niraparib and dostarlimab across multiple cancers has been terminated.
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: A Clinical Trial of Envafolimab Combined With Lenvatinib for Kidney Cancer With Liver Spread [Phase 2]
A Phase 2 clinical trial update indicates a study of Envafolimab in combination with Lenvatinib for clear cell renal cell carcinoma with liv…
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors [Phase 1, Phase 2]
Clinical trial update reports the completion of a Phase 1/2 safety and efficacy study of CTX131 in adults with relapsed or refractory solid …
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Study of BDC-3042 as Single Agent and in Combination With Cemiplimab in Patients With Advanced Malignancies [Phase 1]
This clinical trial update notes the termination of a Phase 1 study of BDC-3042 as a single agent and in combination with cemiplimab in pati…
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Ph2 Study NKT2152 With Palbociclib & Sasanlimab in Subjects With Advanced Clear Cell Renal Cell Carcinoma (ccRcc) [Phase 2]
Phase 2 study evaluating NKT2152 in combination with palbociclib and sasanlimab for advanced clear cell renal cell carcinoma has been termin…
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CLINICAL_TRIALS withdrawal · 2025-11-12Clinical Trial Update: A Study of NKT2152, a HIF2α Inhibitor, in Patients With Advanced Clear Cell Renal Cell Carcinoma [Phase 1, Phase 2]
This clinical trial update reports the termination of a Phase 1/2 study of NKT2152, a HIF2α inhibitor, in patients with advanced clear cell …
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors [Phase 1]
This is a completed Phase 1 clinical trial update evaluating CHS-388 (formerly SRF388) in patients with advanced solid tumors, including cle…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, vs Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)-China Extension Study [Phase 3]
Phase 3 China-extension study comparing pembrolizumab-based regimens (with belzutifan and lenvatinib, or with quavonlimab and lenvatinib) ve…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Ivonescimab Prior to Surgery for the Treatment of High-Risk Localized Clear Cell Renal Cell Cancer [Phase 2]
A Phase 2 clinical trial to evaluate Ivonescimab before surgery for high-risk localized clear cell renal cell carcinoma is not yet recruitin…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors [Phase 1, Phase 2]
A clinical trial update on REGN5678 (Nezastomig) alone or in combination with cemiplimab to treat metastatic castration-resistant prostate c…
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: Pembrolizumab With or Without Axitinib for Clear Cell Kidney Cancer in Patients Undergoing Surgery [Phase 2]
A Phase 2 trial evaluating pembrolizumab with or without axitinib for clear cell renal cell carcinoma in patients undergoing surgery was ter…