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CLINICAL_TRIALS research · 2025-10-07

Clinical Trial Update: Phase I Study of Allogeneic Transforming Growth Factor-beta Receptor Type 2 Knockout CD70 CAR NK Cells in Treatment Refractory Clear Cell Renal Cell Carcinoma [Phase 1]

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Summary

An ongoing Phase I study at MD Anderson tests allogeneic CD70 CAR NK cells engineered with TGF-beta receptor type 2 knockout for treatment-refractory clear cell…

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Diseases / indications

Drugs mentioned

  • Allogeneic Transforming Growth Factor-beta Receptor Type 2 Knockout CD70 CAR NK Cells (TGFBR2 knockout CD70 CAR NK cells)

Snippet

Sponsor: M.D. Anderson Cancer Center | Conditions: Clear Cell Carcinoma, Phase 1 | Phase 1 | Status: RECRUITING