Rhinosinusitis with Nasal Polyps
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Dupilumab for Prevention of Recurrence of CRSwNP After ESS [Phase 4]
Phase 4 trial completion update for dupilumab aimed at preventing recurrence of chronic rhinosinusitis with nasal polyps after endoscopic si…
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CLINICAL_TRIALS research · 2025-02-06Clinical Trial Update: A Cohort Study on Biomarkers to Predict the Efficacy of Biologics for Chronic Rhinosinusitis with Nasal Polyps [Phase 4]
A Phase 4 cohort study at Beijing Tongren Hospital aims to identify biomarkers that predict the efficacy of biologic therapies for chronic r…
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CLINICAL_TRIALS research · 2025-02-03Clinical Trial Update: Development of a Severity Assessment Score for Nasosinus Polyposis (PSI Score)
This completed clinical trial reports the development of the PSI Score, a severity assessment tool for chronic rhinosinusitis with nasal pol…
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: Upper Airway Inflammation and Olfaction: Mechanisms of Loss and Recovery [NA]
This clinical trial investigates the mechanisms of olfactory loss and recovery in chronic rhinosinusitis with nasal polyps, focusing on uppe…
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: Olfactory Outcomes of Dupilumab Treatment for Nasal Polyposis [Phase 4]
Phase 4 study evaluating the effects of dupilumab on sense of smell in nasal polyposis; recruitment is ongoing.
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Opening the "Black Box" on Tezepelumab's Effect on Chronic Rhinosinusitis With Severe Asthma [Phase 3]
This update covers a Phase 3 trial of tezepelumab for patients with asthma and chronic rhinosinusitis with nasal polyps, focusing on its pot…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: Correlation of Preoperative Indices (serum Vit D, Calcium, Phosphorus, FAR, PLR, SII) on Intraoperative Bleeding in CRS
This clinical trial update examines whether preoperative indices (serum vitamin D, calcium, phosphorus, FAR, PLR, and SII) correlate with in…
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: Efficacy and Safety of Mepolizumab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)/ Eosinophilic Chronic Rhinosinusitis (ECRS) [Phase 3]
A Phase 3 study evaluating the efficacy and safety of mepolizumab in adults with chronic rhinosinusitis with nasal polyps and eosinophilic C…
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CLINICAL_TRIALS research · 2024-11-12Clinical Trial Update: Real-life Evaluation of the Efficacy of Biologicals in Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
This clinical trial update describes a real-world evaluation of biological therapies for chronic rhinosinusitis with nasal polyps (CRSwNP). …
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: The Study of CM310 in Patients With Chronic Rhinosinusitis With Nasal Polyps [Phase 2]
A Phase 2 trial evaluating CM310 for chronic rhinosinusitis with nasal polyps has completed.
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: A Study of CM326 in Patients With Chronic Rhinosinusitis With Nasal Polyps [Phase 1, Phase 2]
The Phase 1/2 trial of CM326 for Chronic Rhinosinusitis With Nasal Polyps has completed.
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: NAsal Polyps: Inflammatory & Molecular Phenotyping of Responders to Benralizumab [Phase 3]
Phase 3 trial evaluating inflammatory and molecular phenotyping of responders to benralizumab in nasal polyps has completed.
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Effect of Celecoxib on Postoperative Analgesia and Disease Severity in AERD Patients with CRS [Phase 4]
This Phase 4 clinical trial examines whether celecoxib affects postoperative analgesia and disease severity in patients with aspirin-exacerb…
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CLINICAL_TRIALS other · 2024-09-25Clinical Trial Update: The Study of GR1802 in Patients with Chronic Rhinosinusitis with Nasal Polyps [Phase 2]
This document reports that the Phase 2 study of GR1802 for chronic rhinosinusitis with nasal polyps is currently active but not recruiting.
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CLINICAL_TRIALS research · 2024-09-20Clinical Trial Update: Does Batten Grafting Improve Nasal Outcomes in Septoplasty and Turbinate Reduction? [NA]
A clinical trial is evaluating whether Batten grafting improves nasal outcomes after septoplasty and turbinate reduction and is currently re…
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FDA approval · 2024-09-12FDA Approved: DUPIXENT — Supplemental Application (sanofi-aventis U.S. LLC)
FDA approved a supplemental application for Dupixent (dupilumab) submitted by sanofi-aventis U.S. LLC.
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: Immunologic Impact of Dupilumab in Patients Suffering From Asthma and Chronic Rhinosinusitis With Polyps [Phase 4]
Phase 4 trial assessing the immunologic impact of dupilumab in patients with asthma and chronic rhinosinusitis with nasal polyps; the study …
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Role of Doxycycline in Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
Phase 3 trial evaluating doxycycline for chronic rhinosinusitis with nasal polyps has completed.
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Preclinical Studies of Omalizumab in Chronic Rhinosinusitis With Nasal Polyposis [EARLY_Phase 1]
This update summarizes early-phase studies of omalizumab for chronic rhinosinusitis with nasal polyps, with the trial status listed as compl…
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CLINICAL_TRIALS research · 2024-07-16Clinical Trial Update: BIOlogics in Severe Nasal POlyposis SurvEy.: a French Registry [NA]
Registry entry for a French survey on biologics in severe nasal polyposis; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: A Study in Male and Female Adult Participants With Chronic Rhinosinusitis With Nasal Polyps In the Greater Gulf Region
A completed clinical trial update from Sanofi studying adults with chronic rhinosinusitis with nasal polyps in the Greater Gulf Region.
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Efficacy and Safety of SHR-1905 Injection in Patients With Chronic Rhinosinusitis With Nasal Polyps [Phase 2]
Phase 2 trial update on the efficacy and safety of SHR-1905 injections for chronic rhinosinusitis with nasal polyps; the study is currently …
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CLINICAL_TRIALS research · 2024-06-14Clinical Trial Update: Predictive Factors in Chronic Rhinosinusitis With Nasal Polyps [NA]
A clinical trial update investigating predictive factors in chronic rhinosinusitis with nasal polyps. The current status and trial phase are…
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CLINICAL_TRIALS research · 2024-06-10Clinical Trial Update: Anatomo-clinico-biological Profiles in Severe Nasal Polyps [NA]
This Poitiers University Hospital-sponsored study, Anatomo-clinico-biological Profiles in Severe Nasal Polyps, is currently recruiting to ch…
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CLINICAL_TRIALS withdrawal · 2024-05-09Clinical Trial Update: Early-onset Dupilumab Effects in CRSwNP [Phase 4]
A Phase 4 trial investigating early-onset dupilumab in chronic rhinosinusitis with nasal polyps has been withdrawn.