Rhinosinusitis with Nasal Polyps
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Subjective and Objective Outcome of ESS in CRSwNP [NA]
This clinical trial update indicates ongoing recruitment for a study evaluating subjective and objective outcomes after endoscopic sinus sur…
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CLINICAL_TRIALS trial_result · 2024-04-17Clinical Trial Update: Comparison of Immune Profiles in Chronic Rhinosinusitis Patients After Mepolizumab Treatment [Phase 4]
Phase 4 trial evaluating immune profiles in chronic rhinosinusitis patients after mepolizumab treatment; currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-04-17Clinical Trial Update: th2 Modulation CRSwNP [Phase 4]
Phase 4 trial update for th2 modulation in chronic rhinosinusitis with nasal polyps (CRSwNP); status not yet recruiting.
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FDA approval · 2024-01-25FDA Approved: DUPIXENT — Supplemental Application (sanofi-aventis U.S. LLC)
FDA approved a supplemental application for Dupixent (dupilumab) filed by Sanofi‑Aventis U.S. LLC, indicating an approval of a supplement re…
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CLINICAL_TRIALS trial_result · 2024-01-22Clinical Trial Update: Dupilumab in Japanese Patients With Chronic Rhinosinusitis With Nasal Polyp (SINUS-M52) [Phase 4]
Phase 4 clinical trial update for dupilumab in Japanese patients with chronic rhinosinusitis with nasal polyps; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps [Phase 2]
Phase 2 clinical trial evaluating 611 in chronic rhinosinusitis with nasal polyps; current status unknown based on registry snippet.
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CLINICAL_TRIALS trial_result · 2023-10-17Clinical Trial Update: A Study to Evaluate CBP-201, Rademikibart, in Adult Patients With Chronic Rhinosinusitis With Nasal Polyps [Phase 2]
A Phase 2 trial investigating CBP-201 (Rademikibart) in adults with chronic rhinosinusitis with nasal polyps was terminated with results pos…
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CLINICAL_TRIALS trial_result · 2023-09-18Clinical Trial Update: Study Evaluating the Efficacy and Safety of Intranasal Administration of OPN-375 in Subjects With Chronic Rhinosinusitis With or Without the Presence of Nasal Polyps [Phase 3]
Phase 3 trial results for intranasal OPN-375 in chronic rhinosinusitis with or without nasal polyps have been posted following study complet…
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CLINICAL_TRIALS trial_result · 2023-08-29Clinical Trial Update: The Study of Long-term Outcomes of GR1802 in Patients With Chronic Rhinosinusitis With Nasal Polyps [Phase 2]
Phase 2 clinical trial update for GR1802 in chronic rhinosinusitis with nasal polyps (CRSwNP).
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CLINICAL_TRIALS withdrawal · 2023-08-09Clinical Trial Update: Pre-operative Steroids in CRSsP [Phase 2, Phase 3]
Clinical trial investigating pre-operative steroids in chronic rhinosinusitis with polyps was withdrawn.
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CLINICAL_TRIALS trial_result · 2023-07-05Clinical Trial Update: The Role of Budesonide Intrapolyp Injection in the Management of Type 2 Chronic Rhinosinusitis [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating intrapolyp budesonide injections for managing chronic rhinosinusitis with nasal polyps has been comple…
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CLINICAL_TRIALS trial_result · 2023-06-28Clinical Trial Update: Mepolizumab and In-office Nasal Polypectomy in Patients With Chronic Rhinosinusitis (CRS). A Three Arm Study. [Phase 4]
A Phase 4 clinical trial evaluating mepolizumab in combination with in-office nasal polypectomy for chronic rhinosinusitis with polyps; stat…
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CLINICAL_TRIALS trial_result · 2023-03-10Clinical Trial Update: CST1 Predictive Model of Oral Glucocorticoid Therapy Sensitivity for Chronic Rhinosinusitis With Polyps [Phase 4]
A Phase 4 clinical trial evaluating a CST1 predictive model to gauge sensitivity to oral glucocorticoid therapy in chronic rhinosinusitis wi…
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FDA approval · 2023-01-20FDA Approved: SINUVA — Supplemental Application (Intersect ENT, Inc.)
FDA approved a supplemental application for SINUVA (mometasone furoate) from Intersect ENT, Inc., updating its label.
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CLINICAL_TRIALS trial_result · 2022-10-28Clinical Trial Update: CST1-Guided Oral Glucocorticoids Management for CRSwNP [Phase 4]
Phase 4 trial updating CST1-guided oral glucocorticoid management for chronic rhinosinusitis with nasal polyps.
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CLINICAL_TRIALS trial_result · 2022-05-19Clinical Trial Update: Study Of PF-06817024 In Healthy Subjects, In Patients With Chronic Rhinosinusitis With Nasal Polyps And in Patients With Atopic Dermatitis [Phase 1]
A Phase 1 clinical trial evaluating PF-06817024 in healthy subjects, and in patients with chronic rhinosinusitis with nasal polyps and atopi…
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CLINICAL_TRIALS trial_result · 2022-03-18Clinical Trial Update: Role of Montelukast in the Management of Chronic Rhinosinusitis With Nasal Polyps. [Phase 1, Phase 2]
A early-phase clinical trial investigating montelukast for chronic rhinosinusitis with nasal polyps (CRSwNP) is in Phase 1/Phase 2 with unkn…
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CLINICAL_TRIALS trial_result · 2022-01-24Clinical Trial Update: Etokimab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) [Phase 2]
Phase 2 clinical trial of etokimab in adults with chronic rhinosinusitis with nasal polyps has completed; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2021-07-30Clinical Trial Update: GB001 in Adult Participants With Chronic Rhinosinusitis [Phase 2]
Phase 2 clinical trial update for GB001 in adults with chronic rhinosinusitis, including CRSsNP and CRSwNP; trial completed with results pos…
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CLINICAL_TRIALS trial_result · 2021-06-07Clinical Trial Update: Effect of Postoperative Additive Systemic Steroids in CRSwNP [Phase 4]
Phase 4 trial evaluating postoperative additive systemic steroids in chronic rhinosinusitis with nasal polyps (CRSwNP) has completed.
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CLINICAL_TRIALS trial_result · 2021-05-11Clinical Trial Update: An Extension Study of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
An extension study of omalizumab in chronic rhinosinusitis with nasal polyps completed Phase 3.
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CLINICAL_TRIALS trial_result · 2020-10-28Clinical Trial Update: Itraconazole for Fungal Sensitive Chronic Rhinosinusitis With Nasal Polyps [Phase 2, Phase 3]
A clinical trial update on itraconazole for fungal-sensitive chronic rhinosinusitis with nasal polyps (Phase 2/Phase 3) has been terminated;…
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FDA approval · 2020-04-28FDA Approved: SINUVA — Supplemental Application (Intersect ENT, Inc.)
FDA approves a supplemental application for SINUVA (mometasone furoate) from Intersect ENT, Inc., a steroid-releasing sinus implant used aft…
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CLINICAL_TRIALS trial_result · 2020-03-23Clinical Trial Update: A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
A Phase 3 trial evaluating omalizumab in chronic rhinosinusitis with nasal polyps has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-10-23Clinical Trial Update: Controlled Clinical Study of Dupilumab in Patients With Nasal Polyps [Phase 3]
Phase 3 clinical trial of dupilumab in patients with chronic rhinosinusitis with nasal polyps completed, with results posted.