Rhinosinusitis with Nasal Polyps
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Sign up freeTop drugs studied for this disease
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EMA approval · 2026-08-18EMA Authorised: Dupixent (dupilumab) — Sanofi Winthrop Industrie
The EMA has authorised Dupixent (dupilumab) for multiple indications including atopic dermatitis, prurigo, esophageal diseases, asthma, and …
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CLINICAL_TRIALS trial_result · 2026-08-05Clinical Trial Results: Mechanisms of Smell Improvement With Dupilumab. [Phase 4]
Phase 4 trial results examining mechanisms of smell improvement with dupilumab in chronic rhinosinusitis with nasal polyps.
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CLINICAL_TRIALS trial_result · 2026-06-02Clinical Trial Update: A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
A Phase 3 study evaluating the efficacy, safety, and tolerability of itepekimab (anti-IL-33 monoclonal antibody) in adults with inadequately…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
A Phase 3 study is evaluating itepekimab, an anti-IL-33 monoclonal antibody, for inadequately controlled chronic rhinosinusitis with nasal p…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: BIOlogics in Severe Nasal POlyposis SurvEy
A clinical trial update for a study evaluating biologic therapies in severe nasal polyps associated with chronic rhinosinusitis, currently a…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study to Investigate the Clinical Outcome and Quality of Life in Chinese Post-operative CRSwNP Patients
AstraZeneca-sponsored clinical trial in Chinese postoperative patients with Chronic Rhinosinusitis With Nasal Polyps assessing clinical outc…
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EMA approval · 2026-04-20EMA Authorised: Dupixent (dupilumab) — Sanofi Winthrop Industrie
The EMA authorised Dupixent (dupilumab) for multiple EU indications, including atopic dermatitis, prurigo nodularis, eosinophilic esophagiti…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study to Investigate Changes in Symptoms in Adult Participants With Chronic Rhinosinusitis With Nasal Polyposis Initiating Treatment With Tezepelumab [Phase 3]
A Phase 3 trial update indicates AstraZeneca is initiating a study to evaluate tezepelumab for symptoms in adults with chronic rhinosinusiti…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP) [Phase 3]
A Phase 3 clinical trial evaluating Lebrikizumab (LY3650150) for chronic rhinosinusitis with nasal polyps in participants treated with intra…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Mepolizumab Effectiveness in Patients With Chronic Rhinosinusitis, Nasal Polyps and Comorbid Severe Eosinophilic Asthma
A clinical trial update assessing the effectiveness of mepolizumab for patients with chronic rhinosinusitis with nasal polyps and comorbid s…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Inflammatory Profiles, Histopathological Features, and Remodeling Factors in Chronic Rhinosinusitis With Nasal Polyps [NA]
This clinical trial explores inflammatory profiles, tissue histology, and remodeling factors in chronic rhinosinusitis with nasal polyps.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Long-term Safety and Efficacy Evaluation of Lunsekimig in Adult Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Who Completed a Previous Lunsekimig CRSwNP Study [Phase 2]
This clinical trial update describes a Phase 2 long-term safety and efficacy evaluation of Lunsekimig in adults with chronic rhinosinusitis …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: An Extension Study to Investigate the Long-term Safety and Tolerability of Itepekimab in Adult Participants With Inadequately Controlled Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
An extension Phase 3 trial to assess the long-term safety and tolerability of itepekimab in adults with inadequately controlled chronic rhin…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Evaluation of Nasal Biomarkers for Objective Assessment of Disease Severity in Respiratory Disorders
A completed clinical trial evaluating nasal biomarkers for objective assessment of disease severity in chronic respiratory diseases, includi…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Phenotyping of Type 2 Inflammation Profile by Rheology of Nasal Secretions and Tissue Quantification of Eosinophilic Polymorphonuclear Cells in the Middle Turbinate [NA]
A clinical trial update from University Hospital, Montpellier describing a study to phenotype Type 2 inflammation in chronic rhinosinusitis …
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study to Investigate NPS and Symptoms in Chinese Adult Participants With CRSwNP Initiating Treatment With Tezepelumab [Phase 3]
A Phase 3 clinical trial in Chinese adults with chronic rhinosinusitis with nasal polyps is starting tezepelumab to evaluate nasal polyp sym…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
A Phase 3 clinical trial is evaluating the efficacy, safety, and tolerability of itepekimab, an anti-IL-33 monoclonal antibody, for inadequa…
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CLINICAL_TRIALS other · 2026-04-07Clinical Trial Update: Biologics in Chronic Rhinosinusitis With Nasal Polyposis [Phase 4]
This document reports a Phase 4 clinical trial investigating biologics for chronic rhinosinusitis with nasal polyps. The study is currently …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: ReAl-woRld Evaluation of tEzepelumab for Chronic rhinoSinusitis With Nasal Polyps in Russia
A real-world Russia trial is evaluating tezepelumab for chronic rhinosinusitis with nasal polyps, with asthma as a coexisting condition, and…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Aggravated Airway Inflammation: Research on Biological Treatment (Mepolizumab) [Phase 4]
Phase 4 trial results for mepolizumab in aspirin-induced asthma and chronic rhinosinusitis with nasal polyps have been completed with result…
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: OPN-375 Efficacy and Safety in Adolescents With Bilateral Nasal Polyps [Phase 3]
A Phase 3 trial investigating the efficacy and safety of OPN-375 in adolescents with bilateral nasal polyps is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Adult Japanese Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
A Phase 3 clinical trial evaluating the efficacy, safety, and tolerability of itepekimab (anti-IL-33 mAb) in adult Japanese participants wit…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Viral and Epigenetic Influences in CRSwNP
This entry reports on a clinical trial investigating viral and epigenetic influences in chronic rhinosinusitis with nasal polyps (CRSwNP). T…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Study of Stapokibart Injection in Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) .
A clinical trial is planned to evaluate Stapokibart Injection in patients with chronic rhinosinusitis with nasal polyps, with the study curr…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: A Study of GR1802 in Participants With Chronic Sinusitis With Nasal Polyps [Phase 3]
Phase 3 clinical trial update for GR1802 in chronic rhinosinusitis with nasal polyps; the study is currently active but not recruiting.