Rhinosinusitis with Nasal Polyps
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CLINICAL_TRIALS trial_result · 2026-08-05Clinical Trial Results: Mechanisms of Smell Improvement With Dupilumab. [Phase 4]
Phase 4 trial results examining mechanisms of smell improvement with dupilumab in chronic rhinosinusitis with nasal polyps.
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CLINICAL_TRIALS trial_result · 2026-06-02Clinical Trial Update: A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
A Phase 3 study evaluating the efficacy, safety, and tolerability of itepekimab (anti-IL-33 monoclonal antibody) in adults with inadequately…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Mepolizumab Effectiveness in Patients With Chronic Rhinosinusitis, Nasal Polyps and Comorbid Severe Eosinophilic Asthma
A clinical trial update assessing the effectiveness of mepolizumab for patients with chronic rhinosinusitis with nasal polyps and comorbid s…
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: Aggravated Airway Inflammation: Research on Biological Treatment (Mepolizumab) [Phase 4]
Phase 4 trial results for mepolizumab in aspirin-induced asthma and chronic rhinosinusitis with nasal polyps have been completed with result…
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Adult Japanese Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
A Phase 3 clinical trial evaluating the efficacy, safety, and tolerability of itepekimab (anti-IL-33 mAb) in adult Japanese participants wit…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Mechanisms of Smell Improvement With Dupilumab. [Phase 4]
Phase 4 clinical trial update on the mechanisms by which dupilumab may improve sense of smell in chronic rhinosinusitis with nasal polyps.
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis [Phase 3]
Phase 3 trial update reporting efficacy and safety results for tezepelumab in adults with severe chronic rhinosinusitis with nasal polyps; r…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Efficacy of Long-Term Low Dose Macrolide Therapy in Preventing Early Recurrence of Nasal Polyps After Endoscopic Sinus Surgery [NA]
A completed clinical trial assessing whether long-term low-dose macrolide therapy reduces early recurrence of nasal polyps after endoscopic …
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
Phase 3 results evaluate the efficacy and safety of Depemokimab (GSK3511294) in adults with chronic rhinosinusitis with nasal polyps. The st…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Role of IL-5R Signaling in Non-eosinophil Upper Airway Cells in CRSwNP
A completed clinical trial from Brigham and Women's Hospital studied IL-5R signaling in non-eosinophil upper airway cells in chronic rhinosi…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Regulatory Post-Marketing Surveillance of Xolair® for Chronic Rhinosinusitis With Nasal Polyps
This document reports the completed regulatory post-marketing surveillance study of Xolair (omalizumab) for chronic rhinosinusitis with nasa…
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: A Extension Clinical Study of TQC2731 Injection in the Treatment of Chronic Sinusitis With Nasal Polyps [Phase 2]
This update reports the completion of an extension Phase 2 clinical trial evaluating TQC2731 injection for chronic rhinosinusitis with nasal…
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: EValuating trEatment RESponses of Dupilumab Versus Omalizumab in Type 2 Patients [Phase 4]
Phase 4 trial comparing dupilumab versus omalizumab in Type 2 inflammatory disease patients (chronic rhinosinusitis with nasal polyps and as…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: Dupilumab in Chinese Adult Participants With CRSwNP [Phase 3]
Phase 3 trial evaluating dupilumab in Chinese adults with chronic rhinosinusitis with nasal polyps has completed and results were posted.
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps (ANCHOR-2) [Phase 3]
Phase 3 ANCHOR-2 trial results evaluate the efficacy and safety of depemokimab in participants with chronic rhinosinusitis with nasal polyps…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Participants With Chronic Rhinosinusitis With Nasal Polyps [Phase 2]
This ClinicalTrials.gov entry reports the completion of a Phase 2 study evaluating Verekitug (UPB-101) for chronic rhinosinusitis with nasal…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Tissue Immune Interaction in Nasal Polyposis
A completed clinical trial from the University of California, San Francisco examining tissue immune interactions in nasal polyposis (Chronic…
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: A Clinical Study of TQH2722 Injection in the Treatment of Chronic Sinusitis With or Without Nasal Polyps. [Phase 2]
Phase 2 clinical study of TQH2722 Injection for chronic sinusitis with or without nasal polyps has completed.
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CLINICAL_TRIALS trial_result · 2025-07-01Clinical Trial Update: A Real-world, Head-to-head Comparison of Dupilumab Versus Mepolizumab in Danish Patients With Chronic Rhinosinusitis With Nasal Polyps [Phase 4]
Phase 4 real-world head-to-head trial in Danish patients compares dupilumab with mepolizumab for chronic rhinosinusitis with nasal polyps an…
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: A Clinical Study of TQC2731 Injection in the Treatment of Chronic Rhinosinusitis With Nasal Polyps [Phase 2]
A Phase 2 clinical trial evaluating TQC2731 injection for chronic rhinosinusitis with nasal polyps has completed.
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: Interleukin-4Ra Blockade by Dupilumab Decreases Staphylococcus Colonization and Increases Microbial Diversity in CRSwNP [Phase 4]
A Phase 4 trial update shows that dupilumab, by blocking IL-4 receptor alpha, reduces Staphylococcus aureus colonization and increases micro…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Safety and Efficacy of BHV-3000 (Rimegepant) Orally Disintegrating Tablet for the Acute Treatment of Chronic Rhinosinusitis [Phase 3]
Phase 3 trial evaluating the safety and efficacy of BHV-3000 (rimegepant) orally disintegrating tablet for acute treatment of chronic rhinos…
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Dupilumab for Prevention of Recurrence of CRSwNP After ESS [Phase 4]
Phase 4 trial completion update for dupilumab aimed at preventing recurrence of chronic rhinosinusitis with nasal polyps after endoscopic si…
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: Efficacy and Safety of Mepolizumab in Adults With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)/ Eosinophilic Chronic Rhinosinusitis (ECRS) [Phase 3]
A Phase 3 study evaluating the efficacy and safety of mepolizumab in adults with chronic rhinosinusitis with nasal polyps and eosinophilic C…
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: The Study of CM310 in Patients With Chronic Rhinosinusitis With Nasal Polyps [Phase 2]
A Phase 2 trial evaluating CM310 for chronic rhinosinusitis with nasal polyps has completed.