Myelomonocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: Treatment for Relapsed/Refractory AML Based on a High Throughput Drug Sensitivity Assay [NA]
Clinical trial update on using a high-throughput drug sensitivity assay to guide treatment for relapsed/refractory acute myeloid leukemia.
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CLINICAL_TRIALS withdrawal · 2017-04-05Clinical Trial Update: A Study of Volasertib Plus Induction Chemotherapy for Acute Myeloid Leukemia [Phase 1]
Phase 1 study of volasertib plus induction chemotherapy for acute myeloid leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports completion of a study evaluating an investigational biological therapy in adults with advanced mye…
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CLINICAL_TRIALS trial_result · 2017-03-14Clinical Trial Update: Phase II Hedgehog Inhibitor for Myelodysplastic Syndrome (MDS) [Phase 2]
Phase II trial of a Hedgehog pathway inhibitor in myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML) completed with r…
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Ixazomib (MLN9708) in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update of ixazomib in relapsed or refractory acute myeloid leukemia has been terminated; results were posted previous…
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CLINICAL_TRIALS research · 2017-03-03Clinical Trial Update: Comparison Between Cyclophosphamide and Combination of Methotrexate + Calcineurin Inhibitor for GVHD Prophylaxis [Phase 3]
A Phase 3 trial comparing cyclophosphamide with methotrexate plus a calcineurin inhibitor for GVHD prophylaxis in patients with various hema…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes [Phase 2]
Phase 2 clinical trial evaluating imatinib mesylate in patients with various activated tyrosine kinase-driven malignancies, including hypere…
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CLINICAL_TRIALS trial_result · 2016-12-23Clinical Trial Update: A Study of Gleevec in Patients With Idiopathic Myelofibrosis or Chronic Myelomonocytic Leukemia (CMML) [Phase 2]
Phase 2 study evaluating imatinib (Gleevec) in patients with myelofibrosis and chronic myelomonocytic leukemia has completed. The study was …
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CLINICAL_TRIALS trial_result · 2016-10-20Clinical Trial Update: Study of Azacitidine With or Without Birinapant in Subjects With MDS or CMMoL [Phase 2]
Phase 2 study evaluating azacitidine with or without birinapant in patients with Myelodysplastic syndrome or Chronic myelomonocytic leukemia…
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CLINICAL_TRIALS research · 2016-05-19Clinical Trial Update: Biomarkers in Bone Marrow Samples From Pediatric Patients With High-Risk Acute Myeloid Leukemia
A completed pediatric AML biomarker study update from the Children's Oncology Group examining biomarkers in bone marrow from high-risk AML p…
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CLINICAL_TRIALS trial_result · 2016-05-09Clinical Trial Update: Omacetaxine Mepesuccinate, Cytarabine, and Decitabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating a three-drug regimen of omacetaxine mepesuccinate, cytarabine, and decitabine in older adults with newly diagnosed …
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Korean Post-marketing Surveillance for Sprycel®
This is a completed Korean post-marketing surveillance study of Sprycel (dasatinib). It covered patients with chronic myelomonocytic leukemi…
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CLINICAL_TRIALS trial_result · 2016-03-22Clinical Trial Update: Azacitidine With or Without Lenalidomide or Vorinostat in Treating Patients With Higher-Risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia [Phase 2]
A Phase 2 trial investigates adding lenalidomide or vorinostat to azacitidine in higher-risk myelodysplastic syndromes or chronic myelomonoc…
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CLINICAL_TRIALS trial_result · 2016-03-08Clinical Trial Update: Phase I Clinical Study of CWP232291 in Acute Myeloid Leukemia Patients [Phase 1]
Phase I study of CWP232291 in patients with acute myeloid leukemia and related myeloid neoplasms has completed.
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Phase 1 Study of Terameprocol (EM-1421) in Patients With Leukemia [Phase 1]
Phase 1 study of Terameprocol (EM-1421) in leukemia was terminated; no efficacy results were reported in this update.
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CLINICAL_TRIALS trial_result · 2015-11-13Clinical Trial Update: Non-interventional Study With Azacitidin (Vidaza®)
This document reports a completed non-interventional study of azacitidine (Vidaza) in patients with myelodysplastic syndromes, acute myeloid…
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CLINICAL_TRIALS trial_result · 2015-10-29Clinical Trial Update: A Study of 5-Azacitidine (Vidaza®) in Patients With Chronic Myelomonocytic Leukemia [Phase 2]
Phase 2 study evaluating azacitidine (Vidaza) in patients with chronic myelomonocytic leukemia has completed, and results were posted in 201…
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CLINICAL_TRIALS trial_result · 2015-09-18Clinical Trial Update: Oral Clofarabine Study in Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 trial of oral clofarabine in patients with myelodysplastic syndrome and chronic myelomonocytic leukemia has completed; results were …
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CLINICAL_TRIALS trial_result · 2015-07-28Clinical Trial Update: Phase 1 Study of CC-486 in Japanese Subjects With Hematological Neoplasms [Phase 1]
Termination of a Phase 1 trial evaluating oral azacitidine (CC-486) in Japanese subjects with hematological neoplasms.
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CLINICAL_TRIALS trial_result · 2015-05-01Clinical Trial Update: Study of Lonafarnib Versus Placebo in Subjects With Either Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) (Study P02978AM3)(TERMINATED) [Phase 3]
Phase 3 trial evaluating lonafarnib versus placebo in patients with myelodysplastic syndromes or chronic myelomonocytic leukemia has been te…
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CLINICAL_TRIALS research · 2015-04-24Clinical Trial Update: A Study of the Efficacy and Safety of Lenalidomide Combined to Escalating Doses of Chemotherapy in Intermediate-2-or High Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) With Del 5q [Phase 2]
This is a Phase 2 clinical trial evaluating lenalidomide combined with escalating-dose chemotherapy for intermediate-2 or high-risk myelodys…
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Lenalidomide in Patients With Chronic Myelomonocytic Leukemia [Phase 1, Phase 2]
Clinical trial update indicates ongoing Phase 1 and Phase 2 evaluation of lenalidomide in chronic myelomonocytic leukemia.
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CLINICAL_TRIALS trial_result · 2015-01-08Clinical Trial Update: Aflibercept in Treating Patients With Myelodysplastic Syndromes [Phase 2]
A Phase 2 study of aflibercept in patients with various myelodysplastic syndromes was terminated, with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-01-07Clinical Trial Update: AKT Inhibitor MK-2206 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating AKT inhibitor MK-2206 in relapsed or refractory adult acute leukemias completed; results posted in 2015.
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Belinostat and Azacitidine in Treating Patients With Advanced Hematologic Cancers or Other Diseases [Phase 1]
Phase 1 trial update on belinostat plus azacitidine in adults with advanced hematologic cancers. The study has completed enrollment and eval…