Myelomonocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-12-18Clinical Trial Update: A Safety Study of Lintuzumab in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome [Phase 1]
This document reports the completion of a Phase 1 safety study of lintuzumab in patients with acute myeloid leukemia and myelodysplastic syn…
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CLINICAL_TRIALS trial_result · 2014-11-25Clinical Trial Update: Azacitidine With or Without Entinostat in Treating Patients With Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating azacitidine with or without entinostat in patients with myelodysplastic syndromes, chronic myelomonocytic leukemia,…
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CLINICAL_TRIALS trial_result · 2014-09-01Clinical Trial Update: Sunitinib in Treating Patients With Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia [Phase 2]
Phase 2 clinical trial evaluating sunitinib in patients with chronic myelomonocytic leukemia and myelodysplastic syndromes has completed wit…
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CLINICAL_TRIALS trial_result · 2014-05-21Clinical Trial Update: 3-AP and Fludarabine in Treating Patients With Myeloproliferative Disorders, Chronic Myelomonocytic Leukemia, or Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia [Phase 2]
Phase 2 trial evaluating the combination of Triapine (3-AP) and fludarabine in various myeloproliferative disorders and advanced phases of c…
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CLINICAL_TRIALS trial_result · 2014-03-20Clinical Trial Update: Decitabine in Patients With Chronic Myelomonocytic Leukemia (CMML) [Phase 2]
This clinical trial update reports Phase 2 results for decitabine in patients with chronic myelomonocytic leukemia (CMML).
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CLINICAL_TRIALS trial_result · 2014-02-25Clinical Trial Update: Imatinib Mesylate in Treating Patients With Myelofibrosis [Phase 2]
Phase 2 clinical trial evaluating Imatinib Mesylate in patients with myelofibrosis has completed. The study also addresses related myeloprol…
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CLINICAL_TRIALS trial_result · 2014-02-11Clinical Trial Update: Sorafenib in Myelodysplastic Syndrome [Phase 2]
A Phase 2 trial of sorafenib in myelodysplastic syndromes and chronic myelomonocytic leukemia was terminated, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2014-02-06Clinical Trial Update: Bortezomib and Combination Chemotherapy in Treating Younger Patients With Recurrent, Refractory, or Secondary Acute Myeloid Leukemia [Phase 2]
A Phase 2 trial evaluating bortezomib in combination with chemotherapy for younger patients with recurrent, refractory, or secondary acute m…
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CLINICAL_TRIALS trial_result · 2013-12-16Clinical Trial Update: Tipifarnib in Treating Patients With Myelodysplastic Syndromes [Phase 1]
Phase 1 clinical trial update showing completion of a tipifarnib study in patients with myelodysplastic syndromes and related myeloid disord…
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CLINICAL_TRIALS trial_result · 2013-10-29Clinical Trial Update: Evaluation of Azacitidine in Transfusion Dependent Patients With Low-risk Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) [Phase 2]
Phase 2 clinical trial evaluating azacitidine in transfusion-dependent patients with low-risk myelodysplastic syndrome or chronic myelomonoc…
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CLINICAL_TRIALS trial_result · 2013-09-30Clinical Trial Update: Tanespimycin and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, Chronic Myelomonocytic Leukemia, or Myelodysplastic Syndromes [Phase 1]
Phase 1 trial evaluating Tanespimycin in combination with Cytarabine in adults with relapsed or refractory acute myeloid leukemia, acute lym…
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CLINICAL_TRIALS trial_result · 2013-09-19Clinical Trial Update: Entinostat and Sorafenib Tosylate in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory or Relapsed Acute Myeloid Leukemia [Phase 1]
A Phase 1 trial evaluating the combination of entinostat and sorafenib in patients with advanced or metastatic solid tumors or relapsed/refr…
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CLINICAL_TRIALS trial_result · 2013-08-26Clinical Trial Update: Azacitidine in Treating Patients With Chronic Myelomonocytic Leukemia [Phase 2]
A Phase 2 clinical trial evaluating azacitidine for chronic myelomonocytic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: Combination Chemotherapy With or Without Valspodar in Treating Patients With Previously Untreated Acute Myeloid Leukemia [Phase 3]
Phase 3 trial evaluating whether adding the P-glycoprotein modulator valspodar to standard chemotherapy improves outcomes in adults with pre…
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FDA approval · 2013-05-06FDA Approved: VIDAZA — Supplemental Application (Celgene Corporation)
The FDA approved a Celgene-supplied supplemental application for Vidaza (azacitidine), updating the drug's labeling and/or indications.
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CLINICAL_TRIALS trial_result · 2013-04-04Clinical Trial Update: Evaluation of the Anti-CD-33 Immunotoxin Hum-195/rGel in Patients With Advanced Myeloid Malignancies [Phase 1]
Phase 1 study evaluating Hum-195/rGel, an anti-CD-33 immunotoxin, in patients with advanced myeloid malignancies including acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2013-02-26Clinical Trial Update: Differentiation Therapy With Decitabine in Treating Patients With Myelodysplastic Syndrome [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluates differentiation therapy with decitabine in patients with myelodysplastic syndromes and related conditio…
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CLINICAL_TRIALS trial_result · 2013-02-05Clinical Trial Update: Bortezomib, Daunorubicin, and Cytarabine in Treating Older Patients With Previously Untreated Acute Myeloid Leukemia [Phase 1, Phase 2]
This update reports on a Phase 1/2 clinical trial evaluating the combination of bortezomib, daunorubicin, and cytarabine in older patients w…
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: Thalidomide in Treating Patients With Myelodysplastic Syndrome [Phase 2]
Phase 2 trial of thalidomide for chronic myelomonocytic leukemia and myelodysplastic syndromes has completed. The study investigated thalido…
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: Idarubicin and Cytarabine With or Without Bevacizumab in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
Phase 2 trial of idarubicin and cytarabine with or without bevacizumab for newly diagnosed acute myeloid leukemia was terminated.
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CLINICAL_TRIALS trial_result · 2013-01-23Clinical Trial Update: Liposomal Daunorubicin and SU5416 in Treating Patients With Hematologic Cancer That Has Not Responded to Initial Therapy [Phase 1, Phase 2]
This clinical trial update reports on a completed Phase 1/2 study of liposomal daunorubicin combined with SU5416 for hematologic cancers tha…
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CLINICAL_TRIALS trial_result · 2013-01-09Clinical Trial Update: Chemotherapy Plus Sargramostim in Treating Patients With Refractory Myeloid Cancer [Phase 1]
Phase 1 study assessing the safety of adding sargramostim (GM-CSF) to chemotherapy in patients with refractory myeloid cancers; the trial ha…
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CLINICAL_TRIALS withdrawal · 2012-07-09Clinical Trial Update: Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant [NA]
A clinical trial evaluating mechanical stimulation to prevent bone density loss in patients undergoing donor stem cell transplant has been w…
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CLINICAL_TRIALS trial_result · 2012-04-20Clinical Trial Update: A Phase 1/2 Study of SB1518 for the Treatment of Advanced Myeloid Malignancies [Phase 1, Phase 2]
This document provides an update on the completed Phase 1/2 trial of SB1518 for advanced myeloid malignancies.
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CLINICAL_TRIALS trial_result · 2012-02-22Clinical Trial Update: Study of DT388GMCSF Fusion Protein in Acute Myelogenous Leukemia (AML) and Chronic Myelomonocytic Leukemia (CMML) [Phase 1]
This Phase 1 trial of the DT388GMCSF fusion protein in acute myeloid leukemia and chronic myelomonocytic leukemia was terminated.