Myelomonocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-17Clinical Trial Results: A Study of E7820 in People With Bone Marrow (Myeloid) Cancers [Phase 2]
Phase 2 trial results for E7820 in myeloid bone marrow cancers have been completed with posted results.
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CLINICAL_TRIALS trial_result · 2026-06-08Clinical Trial Results: Recombinant EphB4-HSA Fusion Protein and Azacitidine or Decitabine for Relapsed or Refractory Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia Patients Previously Treated With a Hypomethylating Agent [Phase 2]
Phase 2 trial evaluating recombinant EphB4-HSA with azacitidine or decitabine in relapsed/refractory MDS, CMML, or AML after hypomethylating…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Cobimetinib in Newly Diagnosed or HMA-treated CMML Patients With RAS Pathway Mutations [Phase 2]
Phase 2 trial evaluating cobimetinib in newly diagnosed or HMA-treated CMML patients with RAS pathway mutations has posted results.
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: A Study to Assess Safety, Tolerability and Preliminary Efficacy of Bexmarilimab in Combination With Standard of Care in Patients With Hematological Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Bexmarilimab in combination with standard of care for hematologic malignancies is active but not recru…
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CLINICAL_TRIALS trial_result · 2026-04-17Clinical Trial Update: Enasidenib in MDS &Non-proliferative Chronic Myelomonocytic Leukemia w/o IDH2 Mutation [Phase 1, Phase 2]
This clinical trial update reports Phase 1/2 results for Enasidenib in myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (C…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies [Phase 2]
Phase 2 study evaluating a two-step reduced-intensity conditioning approach for bone marrow transplant in adults with hematologic malignanci…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial update. It evaluates a conditioning strategy using chemotherapy, total body irradiation, and post-transpl…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/2 study of the combination of vorinostat and azacitidine in patients with myelodysplastic syndr…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Decitabine, Cytarabine, and Daunorubicin Hydrochloride in Treating Patients With Acute Myeloid Leukemia [Phase 2]
A Phase 2 clinical trial evaluating the combination of decitabine, cytarabine, and daunorubicin hydrochloride for treatment of Acute Myeloid…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: A Study to Evaluate S227928 as a Single Agent and in Combination With Venetoclax in Patients With R/R AML, MDS/AML, or CMML [Phase 1, Phase 2]
Clinical trial update for S227928 as a single agent and in combination with Venetoclax in relapsed/refractory AML, MDS/AML, and CMML shows t…
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CLINICAL_TRIALS trial_result · 2026-03-18Clinical Trial Update: Study of NMS-03592088 in Patients With Relapsed or Refractory AML or CMML [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating NMS-03592088 in relapsed or refractory acute myeloid leukemia and chronic myelomonocytic leukemia has …
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia [Phase 1]
A Phase 1 trial is evaluating CLAG-M or FLAG-Ida chemotherapy with reduced-intensity conditioning donor stem cell transplant for relapsed or…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: DEC-205/NY-ESO-1 Fusion Protein CDX-1401, Poly ICLC, Decitabine, and Nivolumab in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia [Phase 1]
Phase 1 trial evaluating the safety of a multi-agent regimen (CDX-1401, Poly ICLC, Decitabine, and Nivolumab) in patients with myelodysplast…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: Liposome-encapsulated Daunorubicin-Cytarabine and Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating liposome-encapsulated daunorubicin-cytarabine (CPX-351) in combination with gemtuzumab ozogamicin for relapsed or r…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: LILRB4 STAR-T Cell Therapy for Monocytic Leukemia [NA]
A clinical trial evaluating LILRB4 STAR-T Cell Therapy for monocytic leukemia has completed its study for Acute Myeloid Leukemia and Chronic…
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Guadecitabine and Atezolizumab in Treating Patients With Advanced Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia That Is Refractory or Relapsed [Phase 1, Phase 2]
Phase 1/2 study of guadecitabine plus atezolizumab in adults with advanced myelodysplastic syndrome or chronic myelomonocytic leukemia that …
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CLINICAL_TRIALS trial_result · 2026-01-28Clinical Trial Update: A Safety, Tolerability and Efficacy Study of NC525 in Subjects With Advanced Myeloid Neoplasms [Phase 1]
Phase 1 safety, tolerability and preliminary efficacy study of NC525 in adults with advanced myeloid neoplasms has been terminated and resul…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Dose-Escalation Study of Oral Administration of LP-108 as Monotherapy and in Combination With Azacitidine in Patients With Relapsed or Refractory MDS, CMML, or AML [Phase 1]
Phase 1 dose-escalation trial evaluating LP-108 as monotherapy and in combination with azacitidine in adults with relapsed or refractory mye…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: Efficacy and Safety of HMAs Combined With Venetoclax Versus HMAs Alone in ND Int-and H-risk MDS or CMML
This clinical trial update covers the efficacy and safety of combining hypomethylating agents with venetoclax versus hypomethylating agents …
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: A Phase 1 Trial of CD25/Treg-depleted DLI Plus Ipilimumab for Myeloid Disease Relapse After Matched-HCT [Phase 1]
Phase 1 trial evaluating a combination of CD25/Treg-depleted donor lymphocyte infusion with ipilimumab for relapse of myeloid diseases after…
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN [Phase 1]
This Phase 1 trial update reports adding venetoclax to fludarabine and busulfan conditioning before transplant and to maintenance therapy fo…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes [Phase 2]
Phase 2 trial evaluating adding pomalidomide to the standard liposomal daunorubicin/cytarabine chemotherapy in newly diagnosed acute myeloid…
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: Study of Efficacy and Safety of MBG453 in Combination With Azacitidine in Subjects With Intermediate, High or Very High Risk Myelodysplastic Syndrome (MDS) as Per IPSS-R, or Chronic Myelomonocytic Leukemia-2 (CMML-2) [Phase 3]
Phase 3 study evaluating MBG453 in combination with azacitidine in adults with intermediate/high/very high risk myelodysplastic syndromes (p…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Guadecitabine and Donor Lymphocyte Infusion in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Relapsing After Allogeneic Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating guadecitabine in combination with donor lymphocyte infusion for acute myeloid leukemia, chronic myelomonoc…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: IDH2 Inhibition Using Enasidenib as Maintenance Therapy for IDH2-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantation [Phase 1]
A Phase 1 trial evaluates enasidenib as maintenance therapy for IDH2-mutant myeloid neoplasms after allogeneic stem cell transplantation. Th…