Granulomatous Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Analysis of Patients Treated for Chronic Granulomatous Disease Since January 1, 1995
This document presents a completed analysis of patients treated for Chronic Granulomatous Disease since January 1, 1995.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Genetic Disorders of Mucociliary Clearance in Nontuberculous Mycobacterial Lung Disease
This completed NHLBI study examined genetic disorders that affect mucociliary clearance in nontuberculous mycobacterial lung disease, includ…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patients With Chronic Granulomatous Disease [Phase 1, Phase 2]
This clinical trial update reports on a phase 1/2 study of high-dose peripheral blood stem cell transplantation with post-transplant cycloph…
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: pCCLCHIM-p47 (Lentiviral Vector Transduced CD34 Plus Cells) in Patients With p47 Autosomal Recessive Chronic Granulomatous Disease (AR-CGD) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating pCCLCHIM-p47 lentiviral vector-transduced CD34+ cells for p47 Autosomal Recessive Chronic Granulomatous …
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies [NA]
This clinical trial investigates allogeneic hematopoietic stem cell transplantation as a treatment for primary immune deficiencies, includin…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases [Phase 1, Phase 2]
This clinical trial update describes an early-phase study evaluating sequential cadaveric lung transplantation followed by bone marrow trans…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Elemental Diet for Treatment of Inflammatory Bowel Disease in Patients With Chronic Granulomatous Disease [Phase 2]
Phase 2 clinical trial evaluating an elemental diet for inflammatory bowel disease in patients with chronic granulomatous disease has comple…
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CLINICAL_TRIALS trial_result · 2025-05-02Clinical Trial Update: Study of Gene Therapy Using a Lentiviral Vector to Treat X-linked Chronic Granulomatous Disease [Phase 1, Phase 2]
A Phase 1/2 clinical trial using a lentiviral vector gene therapy to treat X-linked chronic granulomatous disease has completed.
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: Vitamin D3 For CGD Patients With BCGosis/Itis [Phase 2, Phase 3]
Clinical trial update reports completion of Phase 2/3 studies evaluating Vitamin D3 for chronic granulomatous disease patients with BCG-rela…
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating conditioning regimens for allogeneic hematopoietic stem-cell transplantation has completed recruitment…
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CLINICAL_TRIALS trial_result · 2020-11-30Clinical Trial Update: Pharmacokinetics of Posaconazole in Children With Chronic Granulomatous Disease (CGD) [Phase 2]
Phase 2 trial update on the pharmacokinetics of posaconazole in children with Chronic Granulomatous Disease.
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CLINICAL_TRIALS trial_result · 2020-05-01Clinical Trial Update: Haploidentical Transplant for People With Chronic Granulomatous Disease Using Post Transplant Cyclophosphamide [Phase 1, Phase 2]
Phase 1/2 trial update on haploidentical transplant with post-transplant cyclophosphamide for Chronic Granulomatous Disease (CGD); study ter…
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CLINICAL_TRIALS trial_result · 2019-09-17Clinical Trial Update: Plerixafor/G-CSF as Additional Agents for Conditioning Before HSCT in CGD Patients [Phase 2]
Phase 2 clinical trial evaluating Plerixafor with G-CSF as conditioning agents before hematopoietic stem cell transplantation in patients wi…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Effect of IFN-γ on Innate Immune Cells [Phase 1]
Phase 1 trial investigating the effect of interferon-gamma on innate immune cells in chronic granulomatous disease has completed.
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CLINICAL_TRIALS trial_result · 2018-11-09Clinical Trial Update: Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous Disease [Phase 2]
Phase 2 clinical trial update on matched donor transplantation for Chronic Granulomatous Disease with results posted.
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Gene Therapy for Chronic Granulomatous Disease [EARLY_Phase 1]
An early-phase gene therapy trial for Chronic Granulomatous Disease sponsored by NIAID was terminated.
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CLINICAL_TRIALS trial_result · 2018-06-01Clinical Trial Update: Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204) [Phase 2]
Phase 2 trial update for reduced intensity conditioning in hemophagocytic syndromes and selected primary immune deficiencies completed with …
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Evaluating the Transition From Pediatric to Adult Care Among Adolescents With Chronic Granulomatous Disease
This clinical trial update describes the transition from pediatric to adult care for adolescents with chronic granulomatous disease and indi…
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CLINICAL_TRIALS trial_result · 2017-09-20Clinical Trial Update: Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease [Phase 4]
Phase 4 trial update on biochemical response to interferon-gamma in subjects with a CGD gene mutation; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up [Phase 1]
Long-term follow-up data from an early-phase gene therapy trial for Chronic Granulomatous Disease are reported. The document updates on safe…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Use of Busulfan as Conditioning Agent for a Second Stem Cell Transplant [Phase 1]
This update summarizes a Phase 1 trial evaluating busulfan as a conditioning agent for a second stem cell transplant in patients with chroni…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Posaconazole to Treat Invasive Fungal Infections [Phase 3]
Phase 3 trial of posaconazole for invasive fungal infections has completed, involving patients with chronic granulomatous disease and Hyper-…
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CLINICAL_TRIALS trial_result · 2016-06-17Clinical Trial Update: Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood Cells [Phase 2]
Phase 2 study evaluating related hematopoietic stem cell transplantation for several genetic blood disorders; the trial was terminated and r…
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CLINICAL_TRIALS trial_result · 2015-12-29Clinical Trial Update: Infliximab to Treat Crohn'S-like Inflammatory Bowel Disease in Chronic Granulomatous Disease [Phase 1, Phase 2]
Infliximab was studied in a Phase 1/2 trial for Crohn's-like inflammatory bowel disease in patients with chronic granulomatous disease. The …
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation [NA]
Clinical trial update indicating termination of an Alefacept plus allogeneic hematopoietic stem cell transplantation study, with results pos…