Granulomatous Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD) [Phase 1]
Phase 1 clinical trial investigating NADPH oxidase correction in mRNA-transfected granulocyte-enriched cells for Chronic Granulomatous Disea…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Lentiviral Gene Therapy for CGD [NA]
A clinical trial is recruiting to evaluate a lentiviral gene therapy for Chronic Granulomatous Disease.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease With Inflammatory Complications [Phase 1, Phase 2]
An ongoing Phase 1/2 clinical trial is evaluating the safety and efficacy of tofacitinib for Chronic Granulomatous Disease with inflammatory…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide [EARLY_Phase 1]
Clinical trial update on an early-phase haploidentical transplant approach for chronic granulomatous disease using alemtuzumab, busulfan, to…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating base editing of hematopoietic stem and progenitor cells to repair mutations causing X-linked chroni…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Part B- G1X-CGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease [Phase 1, Phase 2]
Ongoing Phase 1/2 clinical trial evaluating G1X-CGD, a lentiviral vector–transduced CD34+ cell therapy for X-linked Chronic Granulomatous Di…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study of the Safety and Efficacy of Prime Editing (PM359) in Participants With p47phox Autosomal Recessive Chronic Granulomatous Disease (CGD ) [Phase 1, Phase 2]
Prime Medicine is conducting a Phase 1/2 study to evaluate the safety and efficacy of PM359, a prime editing therapy, in participants with p…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Evaluation of Patients With Immune Function Abnormalities
The NIAID-sponsored study evaluating patients with immune function abnormalities (chronic granulomatous disease, X-linked severe combined im…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating allogeneic hematopoietic stem cell transplantation for chronic granulomatous disease using alemtuzumab…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes
NIAID-sponsored clinical trial is recruiting to study recruitment and apheresis collection of peripheral blood hematopoietic stem cells, mon…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease
An ongoing clinical trial sponsored by Ensoma is evaluating the prevalence of antibodies and cytokines in participants with Chronic Granulom…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Immune Disorder HSCT Protocol [Phase 2]
Phase 2 clinical trial update on a hematopoietic stem cell transplant protocol for several inherited immune deficiency disorders; the study …
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Study to Assess the Use of JSP191 in Matched Unrelated Donor Transplantation for Chronic Granulomatous Disease (CGD) [EARLY_Phase 1]
This is an early-phase 1 clinical trial update assessing JSP191 in matched unrelated donor transplantation for Chronic Granulomatous Disease…
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CLINICAL_TRIALS research · 2014-09-05Clinical Trial Update: Chronic Granulomatous Disease Study in China
Clinical trial update for Chronic granulomatous disease in China, sponsored by Shanghai Children's Medical Center; current trial status is u…
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CLINICAL_TRIALS research · 2008-03-04Clinical Trial Update: Learning and Behavior Problems in Children With Chronic Granulomatous Disease and Related Disorders
This completed clinical trial update investigates learning and behavior problems in children with chronic granulomatous disease and related …
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CLINICAL_TRIALS research · 2007-11-28Clinical Trial Update: Gene Therapy for Chronic Granulomatous Disease [Phase 1, Phase 2]
Update on a phase 1/2 clinical trial evaluating a gene therapy for chronic granulomatous disease.