Brain Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Development of MRF for Characterization of Brain Tumors After Radiotherapy [NA]
Development of a Magnetic Resonance Framework (MRF) to characterize brain tumors after radiotherapy, with recruitment ongoing at Case Compre…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Motor Eloquent Navigated Transcranial Magnetic Stimulation for Radiosurgery Planning [NA]
This clinical trial investigates motor-eloquent navigated transcranial magnetic stimulation to assist radiosurgery planning for patients wit…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)
GT Medical Technologies reports that the STaRT GammaTiles brain tumor trial is currently recruiting patients with various brain tumors, incl…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: A Study Evaluating Furmonertinib Plus Platinum-based Doublet Chemotherapy Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Sensitizing Mutation-Positive Non-squamous Non-Small Cell Lung Cancer (NSCLC) and Brain Metastases [Phase 3]
A Phase 3 trial evaluating furmonertinib plus platinum-based chemotherapy versus osimertinib in patients with EGFR-sensitizing mutation-posi…
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CLINICAL_TRIALS trial_result · 2026-02-12Clinical Trial Update: Fractionated Stereotactic Radiotherapy for Limited Small Volume Brain Metastases [NA]
The completed clinical trial evaluated fractionated stereotactic radiotherapy for limited small-volume brain metastases. It was sponsored by…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies [NA]
This clinical trial update notes a Mayo Clinic-sponsored feasibility study on intraoperative microdialysis during neurosurgery for central n…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer [Phase 2]
A Phase 2 clinical trial evaluating dendritic cell vaccines targeting Her2/Her3 in combination with pembrolizumab for brain metastases arisi…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain [Phase 2]
An ongoing Phase 2 clinical trial is evaluating stereotactic radiosurgery for patients with lung cancer that has spread to the brain and is …
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CLINICAL_TRIALS trial_result · 2026-02-10Clinical Trial Update: Keto-Brain:Investigating the Use of Ketogenic Diets in Brain Metastases [NA]
A clinical trial evaluating ketogenic diets for brain metastases has been suspended, with recruitment halted for now.
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: A Prospective Cohort Study of Zorifertinib as a First-line Treatment in Patients With Epidermal Growth Factor Receptor-mutant Advanced Non-small Cell Lung Cancer With Central Nervous System (CNS) Metastases
A prospective cohort study evaluating Zorifertinib as first-line therapy for EGFR-mutant advanced non-small cell lung cancer with brain/CNS …
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Study on the Treatment of HER2-negative Breast Cancer Brain Metastases With Radiotherapy Combined With Anlotinib [Phase 2]
Phase 2 clinical trial evaluating radiotherapy combined with Anlotinib for HER2-negative breast cancer with brain metastases; currently recr…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Evaluation of the CONVIVO System [NA]
The CONVIVO System is currently recruiting for a clinical trial evaluating its use in brain tumor surgery. It targets glioblastoma, glioma, …
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases [Phase 1, Phase 2]
A Phase 1/2 trial evaluating the combination of stereotactic radiation and abemaciclib for HR-positive, HER2-negative metastatic breast canc…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Brain Oligometastasis in NSCLC
Clinical trial update for a study on brain oligometastasis in non-small cell lung cancer shows the trial is active but not recruiting.
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Phase II Trial of the PARP Inhibitor Niraparib and PD-1 Inhibitor Dostarlimab in Patients With Advanced Cancers With Active Progressing Brain Metastases (STARLET) [Phase 2]
A Phase II clinical trial evaluating niraparib plus dostarlimab for patients with advanced cancers and active brain metastases. The study is…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors [Phase 1]
A Phase 1 imaging trial evaluating a zirconium-89 labeled antibody (Zr-89 Crefmirlimab Berdoxam) for Immuno-PET imaging of resectable brain …
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT) [Phase 2]
A Phase 2 clinical trial called BIGSHOT evaluating hypofractionated radiotherapy options for brain metastases; the study is currently recrui…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: 18F-FLUC PET/MR in Patients With Brain Mets [Phase 3]
Phase 3 trial evaluating 18F-FLUC PET/MR imaging in patients with brain metastases is currently recruiting. Sponsor is University of Wiscons…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Use of CEST (Chemical Exchange Saturation Transfer) Imaging in PET/MRI [NA]
This clinical trial update describes the use of Chemical Exchange Saturation Transfer (CEST) imaging in PET/MRI for glioma and brain metasta…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Multi-disciplinary Care for Brain Metastases [NA]
A study evaluating multi-disciplinary care for brain metastases is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Retrospective Multicenter Study of Patient-level T1CE/FLAIR MRI Deep Learning to Predict EGFR/ALK Driver Status in NSCLC Brain Metastases With External Validation and Survival Analysis
A retrospective multicenter study using T1CE/FLAIR MRI deep learning to predict EGFR/ALK driver status in brain metastases from non-small ce…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Role of Hyperpolarized 13C-Pyruvate MR Spectroscopy in Patients With Intracranial Metastasis Treated With (SRS) [Phase 1]
Phase 1 trial update evaluating hyperpolarized 13C-pyruvate MR spectroscopy as an imaging biomarker in patients with brain metastases treate…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Furmonertinib 160mg vs 80mg + Chemotherapy in EGFR-Mutated NSCLC With Brain Metastases: Efficacy and Safety Study [Phase 2]
Phase 2 trial evaluating furmonertinib at 160 mg versus 80 mg with chemotherapy in EGFR-mutated non-small cell lung cancer with brain metast…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Niraparib in Tumors Metastatic to the CNS [Phase 2]
Niraparib is being studied in a Phase 2 trial for tumors metastatic to the central nervous system. The study is currently active but not rec…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: GDC-0084 in Combination With Trastuzumab for Patients With HER2-Positive Breast Cancer Brain Metastases [Phase 2]
Phase 2 trial evaluating GDC-0084 in combination with trastuzumab for HER2-positive breast cancer with brain metastases has been terminated.