Brain Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Study of Osimertinib in Patients with a Lung Cancer with Brain or Leptomeningeal Metastases with EGFR Mutation [Phase 2]
Phase 2 trial evaluating Osimertinib in EGFR-mutant non-small cell lung cancer with brain or leptomeningeal metastases has completed. The st…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Keynatinib in Treated Patients With NSCLC and Brain Metastases [Phase 2]
Phase 2 trial of Keynatinib in previously treated non-small cell lung cancer with brain metastases has completed; the update does not detail…
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: Feasibility of the LUM Imaging System for Detection of Cancer to the Brain [NA]
A feasibility trial of the LUM Imaging System for detecting cancer in the brain has been terminated.
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CLINICAL_TRIALS trial_result · 2024-12-30Clinical Trial Update: Study of TY-9591 in Patients With a Lung Cancer With Brain or Leptomeningeal Metastases With EGFR Mutation [Phase 2]
A Phase 2 trial of TY-9591 in non-small cell lung cancer with EGFR activating mutation and brain or leptomeningeal metastases has completed.
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: MR-Linac Guided Adaptive FSRT for Brain Metastases From Non-small Cell Lung Cancer [Phase 2]
Completed Phase 2 trial evaluating MR-Linac guided adaptive FSRT for brain metastases in non-small cell lung cancer.
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Study on Prevalence and Impact of Brain Metastases on Survival in Lung Cancer by Line of Treatment
This completed clinical trial update examines how prevalent brain metastases are in lung cancer and assesses their impact on survival across…
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Safety Study of Pritumumab in Brain Cancer [Phase 1]
Phase 1 safety study of Pritumumab in adult brain cancer patients with malignant primary brain tumors and brain metastases has completed.
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CLINICAL_TRIALS trial_result · 2024-11-13Clinical Trial Update: Study to Evaluate the Safety and Efficacy of Serplulimab Plus Bevacizumab and Chemotherapy in NSCLC Patients With Brain Metastases [Phase 2, Phase 3]
Phase 2/3 study evaluating the safety and efficacy of serplulimab plus bevacizumab and chemotherapy in non-small cell lung cancer patients w…
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: ARRY-380 + Trastuzuamab for Breast w/ Brain Mets [Phase 1]
Phase 1 trial evaluating ARRY-380 in combination with trastuzumab for brain metastases in HER2-positive breast cancer. The study status is c…
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CLINICAL_TRIALS trial_result · 2024-10-22Clinical Trial Update: Advanced MRI Scan Before and After Radiation Therapy for the Detection of Intracranial Metastasis [NA]
Clinical trial results assess the use of advanced MRI before and after radiation therapy to detect intracranial metastases in patients with …
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Pembro+Chemo in Brain Mets [Phase 2]
Phase 2 trial of pembrolizumab plus chemotherapy for brain metastases from lung cancer was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery [Phase 1]
APN401 was evaluated in a Phase 1 trial for patients with recurrent or metastatic pancreatic cancer, colorectal cancer, and unresectable sol…
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CLINICAL_TRIALS trial_result · 2024-09-27Clinical Trial Update: Blood Brain Barrier Differences in Patients with Brain Tumors Undergoing Surgery
This completed clinical trial examined differences in the blood-brain barrier in patients with brain tumors undergoing surgical resection.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Radiosurgery Dose Reduction for Brain Metastases on Immunotherapy (RADREMI): A Prospective Pilot Study [NA]
RADREMI was a prospective pilot study evaluating dose reduction of radiosurgery for brain metastases in patients receiving immunotherapy; th…
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CLINICAL_TRIALS trial_result · 2024-08-23Clinical Trial Update: Comparaison Between MRI Alone or Combined With Positron Emission Tomography for Brain Metastasis Diagnosis
A completed clinical trial compared MRI alone to MRI combined with PET for diagnosing brain metastases, assessing whether adding PET improve…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Intraoperative Laser Speckle Contrast Imaging of Cerebral Blood Flow
Clinical trial update on using intraoperative laser speckle contrast imaging to monitor cerebral blood flow during brain procedures across s…
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: GM1 Prophylaxis for WBRT Related Cognitive Dysfunction [Phase 3]
A Phase 3 trial evaluating GM1 ganglioside prophylaxis to prevent whole-brain radiotherapy-related cognitive dysfunction in patients with br…
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CLINICAL_TRIALS trial_result · 2024-07-17Clinical Trial Update: Hypofractionated Brain Radiationcavity [NA]
Clinical trial update indicates the hypofractionated brain radiation trial for brain metastases has completed; no results are provided in th…
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastases [Phase 2]
Phase 2 clinical trial update evaluating the combination of radiosurgery and nivolumab for brain metastases in various cancers, with complet…
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Pilot Phase 2 Study Whole Brain Radiation Therapy With Simultaneous Integrated Boost for Patients With Brain Metastases [NA]
The pilot Phase 2 trial evaluating whole brain radiation therapy with simultaneous integrated boost for brain metastases was terminated; res…
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases [EARLY_Phase 1]
This early-phase trial evaluates 18F-FMAU PET/CT with MRI to detect brain tumors in patients with brain cancer or brain metastases. The stud…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: HKI-272 for HER2-Positive Breast Cancer and Brain Metastases [Phase 2]
Phase 2 trial update for neratinib (HKI-272) in HER2-positive breast cancer with brain metastases; the study completed and results have been…
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: A Retrospective Study of the Efficacy and Safety of Lolatinib in ALK+ NSCLC Patients With Brain or Meningeal Metastasis
A retrospective study evaluating the efficacy and safety of Lolatinib in ALK-positive non-small cell lung cancer patients with brain metasta…
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Nivo/Ipi Combination Therapy in Symptomatic Brain Metastases [Phase 2]
Phase 2 clinical trial evaluating the nivolumab and ipilimumab combination in symptomatic melanoma with brain metastases has been terminated…
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: Dual Time Point FDG PET/MRI Scan in Improving the Imaging Cancer Patients With Brain Metastases [Phase 4]
Phase 4 clinical trial assessing a dual time-point FDG PET/MRI protocol to improve imaging of brain metastases; trial status is completed.