Brain Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-03-06Clinical Trial Update: Prophylactic Cranial Irradiation (PCI) Versus no PCI in Non Small Cell Lung Cancer After a Response to Chemotherapy [Phase 3]
Phase 3 trial comparing prophylactic cranial irradiation versus no PCI in non-small cell lung cancer patients after chemotherapy response; t…
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CLINICAL_TRIALS trial_result · 2017-03-01Clinical Trial Update: Icotinib or Whole Brain Irradiation in EGFR-mutant Lung Cancer [Phase 3]
A Phase 3 randomized trial comparing icotinib with whole brain irradiation in patients with EGFR-mutant non-small cell lung cancer and brain…
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: Response of Brain Metastases After Gamma-Knife Radiosurgery Using Dynamic Susceptibility-weighted Contrast-enhanced Perfusion Magnetic Resonance Imaging [Phase 1]
Phase 1 trial evaluating response of brain metastases to Gamma Knife radiosurgery, assessed with dynamic susceptibility-weighted contrast-en…
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CLINICAL_TRIALS trial_result · 2017-02-08Clinical Trial Update: Toronto BNB Pilot Study
Clinical trial NCT02082587, the Toronto BNB Pilot Study, has completed.
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CLINICAL_TRIALS trial_result · 2016-12-29Clinical Trial Update: Perfexion Brain Metastasis [Phase 1]
A Phase 1 clinical trial of Perfexion for brain metastases has been terminated.
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: A Study of Whole Brain Radiation Therapy and Capecitabine in Breast Cancer Participants With Newly Diagnosed Brain Metastasis [Phase 2]
This update reports the termination of a Phase 2 study evaluating whole brain radiation therapy in combination with capecitabine for breast …
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CLINICAL_TRIALS trial_result · 2016-10-21Clinical Trial Update: Using Intensity Modulated Radiation Therapy (IMRT) for Brain Metastases [Phase 1]
Phase 1 clinical trial evaluating the use of intensity modulated radiation therapy (IMRT) for brain metastases.
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CLINICAL_TRIALS trial_result · 2016-09-23Clinical Trial Update: Hypofractionated Stereotactic Radiation Therapy of Brain Metastases: Evaluation of Whole-brain Radiotherapy
The clinical trial evaluating hypofractionated stereotactic radiotherapy for brain metastases with evaluation of whole-brain radiotherapy ha…
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CLINICAL_TRIALS trial_result · 2016-09-22Clinical Trial Update: A Trial of Postoperative Whole Brain Radiation Therapy vs. Salvage Stereotactic Radiosurgery Therapy for Metastasis [Phase 3]
Completed Phase 3 trial comparing postoperative whole-brain radiation therapy to salvage stereotactic radiosurgery for brain metastases.
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CLINICAL_TRIALS trial_result · 2016-08-29Clinical Trial Update: Investigate the Maximum Tolerated Dose of Vandetanib and Concurrent Whole Brain Radiotherapy (WBRT) in Patients With Non-small Cell Lung Cancer (NSCLC) and Brain Metastases [Phase 1]
This Phase 1 trial assessed the maximum tolerated dose of vandetanib when given with whole brain radiotherapy in patients with non-small cel…
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CLINICAL_TRIALS trial_result · 2016-08-25Clinical Trial Update: Phase Ⅲ Trial of WBRT Versus Erlotinib Concurrent Whole-brain Radiation Therapy as first-line Treatment for Patients With Multiple Brain Metastases From Non-small-cell Lung Cancer(ENTER): a Multicentre, Open-label, Randomised Study [Phase 3]
A multicenter Phase 3 randomized study comparing whole-brain radiation therapy alone to erlotinib given with WBRT as first-line treatment in…
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CLINICAL_TRIALS trial_result · 2016-08-09Clinical Trial Update: A Phase II Study of Dacomitinib in Progressive Brain Metastases [Phase 2]
This clinical trial update notes the termination of a Phase II study of dacomitinib in progressive brain metastases, with results posted in …
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CLINICAL_TRIALS trial_result · 2016-07-28Clinical Trial Update: Supplementation of L-arginine in Patients With Non-resectable Brain Metastases [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating supplementation with L-arginine in patients with unresectable brain metastases has completed.
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CLINICAL_TRIALS trial_result · 2016-07-13Clinical Trial Update: GRN1005 Alone or in Combination With Trastuzumab in Breast Cancer Patients With Brain Metastases [Phase 2]
A Phase 2 study evaluating GRN1005 alone or with trastuzumab in breast cancer patients with brain metastases has completed (status: COMPLETE…
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CLINICAL_TRIALS trial_result · 2016-07-07Clinical Trial Update: Radiosurgery With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases [Phase 3]
Phase 3 trial comparing radiosurgery with vs. without whole-brain radiation therapy for brain metastases has completed.
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CLINICAL_TRIALS trial_result · 2016-06-06Clinical Trial Update: Stereotactic Radiation Therapy in Treating Patients With Brain Metastases [NA]
The document reports the completion of a clinical trial evaluating stereotactic radiation therapy for brain metastases, with results posted …
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CLINICAL_TRIALS trial_result · 2016-05-30Clinical Trial Update: Neurocognition After Gamma Knife Radiosurgery for Multiple Brian Metastases
A clinical trial studying neurocognition after Gamma Knife radiosurgery for patients with multiple brain metastases has been terminated.
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: A Phase II Multi-institutional Study Assessing Simultaneous In-field Boost Helical Tomotherapy for 1-3 Brain Metastases [Phase 2]
A Phase II multi-institutional trial evaluating simultaneous in-field boost with Helical Tomotherapy for patients with 1-3 brain metastases …
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CLINICAL_TRIALS trial_result · 2016-04-11Clinical Trial Update: Non Invasive Methods for Differential Diagnosis Radionecrosis/Recurrence After Radiosurgery of Brain Metastases [Phase 3]
Phase 3 trial evaluating non-invasive methods to differentiate radionecrosis from recurrence after radiosurgery for brain metastases; the st…
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CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: A Study Evaluating INIPARIB in Combination With Chemotherapy to Treat Triple Negative Breast Cancer Brain Metastasis [Phase 2]
This clinical trial update reports the completion of a Phase 2 study evaluating INIPARIB in combination with chemotherapy for triple-negativ…
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CLINICAL_TRIALS trial_result · 2016-02-22Clinical Trial Update: Phase II Trial of Stereotactic Radiosurgery Boost Following Surgical Resection for Brain Metastases [Phase 2]
Phase II trial evaluating stereotactic radiosurgery boost after surgical resection for brain metastases has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Simvastatin Effect on Radiation Therapy of Brain Metastases [Phase 2]
Phase 2 clinical trial evaluating simvastatin in combination with radiation therapy for brain metastases has completed, with the study statu…
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CLINICAL_TRIALS trial_result · 2016-01-25Clinical Trial Update: Ipilimumab Combined With a Stereotactic Radiosurgery in Melanoma Patients With Brain Metastases [Phase 2]
This phase 2 trial evaluates ipilimumab in combination with stereotactic radiosurgery for melanoma patients with brain metastases. The study…
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CLINICAL_TRIALS trial_result · 2016-01-18Clinical Trial Update: Temozolomide and Vinorelbine in Treating Patients With Recurrent Brain Metastases [Phase 1, Phase 2]
This update reports results from a Phase 1/2 clinical trial evaluating the combination of temozolomide and vinorelbine in patients with recu…
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CLINICAL_TRIALS trial_result · 2015-12-18Clinical Trial Update: A Feasibility Study of Image Guided Noninvasive Single Fraction Stereotactic Radiosurgery for the Treatment of Brain Metastases
This document reports the completion of a feasibility study assessing image-guided noninvasive single-fraction stereotactic radiosurgery for…