Brain Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Feasibility of 18F-Fluciclovine PET/CT to Identify Brain Metastasis [Phase 2]
A Phase 2 feasibility trial at the University of Arizona is evaluating the radiotracer 18F-Fluciclovine PET/CT to identify brain metastases.
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Corticodependent or Corticoresistant Brain Radionecrosis After Radiotherapy for Brain Metastases [Phase 3]
A Phase 3 clinical trial evaluating corticodependent or corticoresistant brain radionecrosis after radiotherapy for brain metastases, curren…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: MRI Following Stereotactic Radiosurgery (SRS) for Brain Metastases [NA]
Clinical trial update on MRI after stereotactic radiosurgery for brain metastases; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Exploration of the Safety and Efficacy of T-DXd Concurrent With Brain Radiotherapy in Patients With Brain Metastases HER2-positive/HER2-low Advanced Breast Cancer [NA]
A clinical trial is exploring the safety and efficacy of trastuzumab deruxtecan (T-DXd) given concurrently with brain radiotherapy in patien…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer
This clinical trial is evaluating the molecular-genetic concordance between primary colorectal tumors and brain metastases and is currently …
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Trastuzumab Rezetecan Combined With Radiotherapy Versus Trastuzumab Rezetecan in the Treatment of HER2-positive Advanced Breast Cancer With Brain Metastases [Phase 2]
This Phase 2 clinical trial is comparing trastuzumab rezetecan with radiotherapy versus trastuzumab rezetecan alone in patients with HER2-po…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: ASL in Brain Metastasis MRI Following Gamma Knife Treatment [NA]
A clinical trial is evaluating arterial spin labeling (ASL) MRI for monitoring brain metastases after Gamma Knife treatment; the study is cu…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Multimodal Large Model-Driven Risk and Prognosis Assessment for Brain Metastases in Lung Cancer
This document reports a clinical trial investigating AI-driven risk and prognosis assessment for brain metastases in non-small cell lung can…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Automated Detection of Brain Metastases on MRI
Clinical trial update for Robovision BV's automated MRI detection system for brain metastases, currently enrolling by invitation.
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: SRS/SRT/Hypo-RT Versus HA-WBRT for No More Than 10 Brain Metastases in SCLC [Phase 3]
Phase 3 clinical trial comparing SRS/SRT/Hypo-RT to hippocampal-avoidance whole-brain radiotherapy for patients with up to 10 brain metastas…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Neurocognitive Functioning With Genu-Sparing Whole Brain Radiation Therapy for Brain Metastases [NA]
This clinical trial is evaluating neurocognitive functioning with genu-sparing whole brain radiation therapy for brain metastases and is cur…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Neoadjuvant Radiosurgery for Resectable Brain Metastases: Phase I/II Study [Phase 1, Phase 2]
A Phase I/II clinical trial evaluating neoadjuvant radiosurgery for patients with resectable brain metastases, currently recruiting.
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: Risk and Prognosis of Brain Metastasis in Non-Small Cell Lung Cancer
A registered clinical trial sponsored by Fudan University investigates the risk and prognosis of brain metastases in patients with non-small…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Diagnostic Assessment of Amino Acid PET/MRI in the Evaluation of Glioma and Brain Metastases
This clinical trial is evaluating amino acid PET/MRI for the evaluation of glioma and brain metastases. The study is currently recruiting an…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Glutamate Excitotoxicity in Brain Metastases From Lung, Breast and Melanoma Treated With Stereotactic Radiosurgery
ClinicalTrials.gov entry for a study on glutamate excitotoxicity in brain metastases from lung cancer, breast cancer, and melanoma treated w…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: Characterization of Circulating and Tumor-infiltrating Immune Cells in Malignant Brain Tumors
A recruiting clinical trial characterizes circulating and tumor-infiltrating immune cells in malignant brain tumors to study the immune envi…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Intraoperative Radiotherapy in Patients With Brain Metastases [NA]
ClinicalTrials.gov updates a study evaluating intraoperative radiotherapy for brain metastases, currently in the recruitment phase.
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: A Ketogenic Diet as a Complementary Treatment on Patients With High-grade Gliomas and Brain Metastases [NA]
A clinical trial at Attikon Hospital is evaluating the ketogenic diet as a complementary treatment for patients with high-grade gliomas and …
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Efficacy of the Association of Fractionated SRS and Subsequent Surgery in Patients With Brain Metastases [NA]
This clinical trial update reports on the efficacy of using fractionated stereotactic radiosurgery followed by surgery for brain metastases;…
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CLINICAL_TRIALS research · 2025-05-22Clinical Trial Update: Phase I Study of Fractionated Stereotactic Radiation Therapy [Phase 1]
Phase I study evaluating fractionated stereotactic radiation therapy for Brain metastases. The trial is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: 18F-Fluciclovine PET Amino Acid Evaluation of Brain Metastasis Treated With Stereotactic Radiosurgery [Phase 1]
A Phase 1 clinical trial evaluating 18F-fluciclovine PET imaging for brain metastases treated with stereotactic radiosurgery is currently re…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Intraoperative Sonographically Versus Fluorescence-guided Resection of Contrast-enhancing Gliomas and Brain Metastases [NA]
Clinical trial comparing intraoperative sonography to fluorescence-guided resection for contrast-enhancing gliomas and brain metastases has …
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: General Anesthesia Versus Awake Surgery in Resection of Gliomas and Metastases of Motor Areas [NA]
A clinical trial comparing general anesthesia versus awake surgery for resection of gliomas and brain metastases in motor cortex regions; th…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Concurrent Fluorescence and Sonographically Guided Eradication of Contrast-enhancing Gliomas and Metastases [NA]
This clinical trial update reports a recruitment-status study (NCT05474573) evaluating fluorescence- and ultrasound-guided eradication of co…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: Avoiding Radiation Therapy Due to Intracranial Response to Chemotherapy, Targeted Therapy and/or Immuno-ONcology Therapy for Brain Metastases: Pilot Pragmatic Trial [Phase 2]
This is a Phase 2 pilot pragmatic clinical trial updating on strategies to avoid radiation therapy for brain metastases in NSCLC patients wh…