Brain Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-06-14Clinical Trial Update: Radiotherapy of Multiple Brain Metastases Using AGuIX® [Phase 2]
A Phase 2 clinical trial is evaluating radiotherapy for multiple brain metastases using the AGuIX nanoparticle radiosensitizer. The current …
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CLINICAL_TRIALS research · 2024-05-30Clinical Trial Update: Immune Treatment of Brain Metastasis of Lung Cancer Combined With Large-segmentation Precision Radiotherapy [Phase 2]
A Phase 2 clinical trial in non-small cell lung cancer with brain metastases is currently recruiting, evaluating an immune therapy in combin…
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: Closed vs. Open Face Masks for Cranial Radiotherapy [NA]
This clinical trial update notes the completion of a study comparing closed versus open face masks for cranial radiotherapy in patients with…
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: Imaging Features for the Risks for Recurrence After Stereotactic Radiosurgery in Brain Metastasis
A recruiting trial evaluating imaging features to assess the risk of recurrence after stereotactic radiosurgery for brain metastases.
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: Cilengitide and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases From Lung Cancer [Phase 1]
A Phase 1 trial evaluating cilengitide in combination with whole-brain radiation therapy for brain metastases arising from lung cancer has b…
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: SGM-101 in Colorectal Brain Metastases. [Phase 2]
Phase 2 clinical trial evaluating SGM-101 for colorectal cancer with brain metastases is currently recruiting at Leiden University Medical C…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Neoadjuvant vs. Intraoperative vs. Adjuvant Resection Cavity Radiotherapy of Brain Metastases [Phase 2]
A Phase 2 study comparing neoadjuvant, intraoperative, and adjuvant resection cavity radiotherapy for brain metastases is currently recruiti…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Magnetic Resonance Imaging-guided Adaptive Radiotherapy for Large Brain Metastases
This document provides an update on an ongoing clinical trial evaluating magnetic resonance imaging-guided adaptive radiotherapy for patient…
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CLINICAL_TRIALS research · 2024-05-07Clinical Trial Update: LIFE - Lung Cancer, Immunotherapy, Frailty, Effect
The LIFE trial update describes a study of non-small cell lung cancer examining immunotherapy with attention to frailty and quality-of-life …
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CLINICAL_TRIALS research · 2023-06-01Clinical Trial Update: nTMS for Motor Mapping of Rolandic Lesions [Phase 2, Phase 3]
Clinical trial update on navigated transcranial magnetic stimulation (nTMS) for motor mapping in Rolandic region lesions, with Phase 2 and P…
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CLINICAL_TRIALS research · 2019-02-19Clinical Trial Update: High Dose Icotinib With Sequential SRS For NSCLC Patients Harboring EGFR Mutation With Brain Metastases [Phase 2]
A Phase 2 clinical trial evaluating high-dose icotinib in combination with sequential stereotactic radiosurgery (SRS) for patients with EGFR…
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CLINICAL_TRIALS research · 2018-05-18Clinical Trial Update: Short Course Radiation Therapy in Palliative Treatment of Brain Metastases [NA]
This document provides an update on a clinical trial evaluating a short-course radiation therapy approach for palliation in patients with br…
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CLINICAL_TRIALS research · 2018-05-17Clinical Trial Update: Protocol for Evaluating a Planning Algorithm for Gamma Knife Radiosurgery
This document describes a protocol to evaluate a planning algorithm for Gamma Knife radiosurgery across vestibular schwannoma, brain metasta…
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CLINICAL_TRIALS research · 2018-02-28Clinical Trial Update: Pharmacokinetics of Systemic Anti-Cancer Therapies in the Cerebrospinal Fluid (CSF) of Patients With Advanced Cancer
This clinical trial update describes pharmacokinetic measurements of systemic anti-cancer therapies in the cerebrospinal fluid of patients w…
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CLINICAL_TRIALS research · 2017-12-11Clinical Trial Update: PET/CT Evaluation of Primary and Metastatic Brain Tumors With a Novel Radioiodinated Phospholipid Ether Analogue I-NM404 [NA]
Clinical trial evaluating PET/CT imaging using I-NM404 for glioblastoma multiforme and brain metastases; study completed with results posted…
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CLINICAL_TRIALS research · 2017-08-22Clinical Trial Update: A Study of the Gene Mutation Status in Cerebrospinal Fluid, Blood and Tumor Tissue of Non-small Cell Lung Cancer Patients With Brain Metastases
This clinical trial update outlines a study assessing gene mutation status in cerebrospinal fluid, blood, and tumor tissue from patients wit…
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CLINICAL_TRIALS research · 2017-06-01Clinical Trial Update: PCI in Advanced Triple Negative Breast Cancer Patients Who Response to 1st Line Chemotherapy [NA]
This document provides a clinical trial update on the use of prophylactic cranial irradiation in advanced triple-negative breast cancer pati…
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CLINICAL_TRIALS research · 2017-05-03Clinical Trial Update: Buparlisib in Melanoma Patients Suffering From Brain Metastases (BUMPER) [Phase 2]
Phase 2 clinical trial update for buparlisib in melanoma patients with brain metastases (BUMPER). The current status of the trial is UNKNOWN…
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CLINICAL_TRIALS research · 2017-01-24Clinical Trial Update: Detection of CSF Next Generation Sequencing in the Application of Brain Metastases From Lung Adenocarcinoma or Meningeal Metastasis
A clinical trial sponsored by Shandong Cancer Hospital and Institute is evaluating cerebrospinal fluid next-generation sequencing for detect…
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CLINICAL_TRIALS research · 2017-01-23Clinical Trial Update: Tomotherapy for Refractory Brain Metastases [NA]
This clinical trial update discusses using Tomotherapy to treat refractory brain metastases. The current status of the trial is UNKNOWN.
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CLINICAL_TRIALS research · 2016-12-23Clinical Trial Update: Hippocampal-sparing Whole Brain Radiotherapy for Brain Metastases From Breast Cancer [NA]
Clinical trial update on hippocampal-sparing whole-brain radiotherapy for brain metastases arising from breast cancer. The current status of…
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CLINICAL_TRIALS research · 2016-11-23Clinical Trial Update: Open Label, Prospective Study to Investigate Efficacy and Safety of AZD9291 in BM From NSCLC Patients With EGFR T790M [Phase 3]
Open-label Phase 3 study evaluating the efficacy and safety of osimertinib (AZD9291) in brain metastases from EGFR T790M-positive non-small …
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CLINICAL_TRIALS research · 2016-09-21Clinical Trial Update: Effect of TTFields (150kHz) in Non-small Cell Lung Cancer (NSCLC) Patients With 1-5 Brain Metastases Following Optimal Standard Local Treatment (COMET) [Phase 2]
Phase 2 COMET trial evaluating Tumor Treating Fields at 150 kHz in non-small cell lung cancer patients with 1-5 brain metastases after stand…
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CLINICAL_TRIALS research · 2016-07-14Clinical Trial Update: A Clinical Trial on Whole-brain Radiotherapy With Temozolomide Concurrent Chemotherapy or Avoidance of Hippocampus for Patients of Brain Metastases [Phase 2]
A Phase 2 clinical trial evaluating whole-brain radiotherapy with concurrent temozolomide versus hippocampal avoidance in patients with brai…
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CLINICAL_TRIALS research · 2016-06-23Clinical Trial Update: Exploring the Role of 3T MRI in Gamma Knife Radiosurgery
This record notes a completed clinical trial evaluating the role of 3T MRI in planning Gamma Knife radiosurgery for brain metastases.