Atypical Teratoid Rhabdoid Tumor
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors [Phase 1]
Phase 1 clinical trial evaluating B7-H3–specific CAR T cell therapy delivered locoregionally for diffuse intrinsic pontine glioma/diffuse mi…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors [Phase 1, Phase 2]
Clinical trial update of a tiragolumab plus atezolizumab combination for relapsed or refractory SMARCB1/SMARCA4-deficient tumors, spanning P…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: GPC3 CAR T Cells With IL-15 and IL-21 for Recurrent ATRT and CNS Rhabdoid Tumors (RADIANT) [Phase 1]
Phase 1 trial evaluating GPC3 CAR T cells with IL-15 and IL-21 for recurrent atypical teratoid rhabdoid tumor and CNS rhabdoid tumors; curre…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors [Phase 2]
An update on a Phase 2 trial of alisertib for malignant rhabdoid tumors and atypical teratoid rhabdoid tumors, with the study currently acti…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: An Intermediate Expanded Use Trial of DFMO
This is an update on an intermediate expanded-use trial of DFMO for neuroblastoma and several embryonal CNS tumors, including medulloblastom…
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CLINICAL_TRIALS trial_result · 2026-02-05Clinical Trial Update: B7-H3.CD28Z.CART in CNS Neoplasms [Phase 1]
A Phase 1 clinical trial evaluating B7-H3.CD28Z.CART for central nervous system neoplasms is currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-17Clinical Trial Update: EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors [Phase 1]
Phase 1 trial evaluating locoregional EGFR806-specific CAR T cells for EGFR-positive pediatric CNS tumors. The study status is completed.
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Finding New Targets by Proteomic Approaches (InnovRT1)
This clinical trial update reports a completed study (InnovRT1) investigating proteomic approaches to identify new targets for atypical tera…
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: A Study of Tazemetostat in Adult Participants With Soft Tissue Sarcoma [Phase 2]
Phase 2 study of tazemetostat in adult participants with soft tissue sarcoma, including rhabdoid tumors, has completed and results were post…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: Feasibility of Using Bortezomib With or Without Chemotherapy in Patients With Atypical Teratoid/Rhabdoid Tumors [Phase 2]
Phase 2 trial update evaluating the feasibility of adding bortezomib, with or without standard chemotherapy, in patients with atypical terat…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: A Study of Panobinostat in Pediatric Patients With Solid Tumors Including MRT/ATRT [Phase 2]
This is a Phase 2 clinical trial update for panobinostat in pediatric solid tumors including malignant rhabdoid tumor and atypical teratoid/…
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CLINICAL_TRIALS trial_result · 2021-08-27Clinical Trial Update: Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors [Phase 1]
Phase 1 trial evaluating ribociclib with everolimus in pediatric patients with recurrent or refractory malignant brain tumors; completed wit…
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CLINICAL_TRIALS trial_result · 2017-08-07Clinical Trial Update: p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors [Phase 1]
This Phase 1 trial tests the safety of the p28 peptide in younger patients with recurrent or progressive central nervous system tumors and t…
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CLINICAL_TRIALS trial_result · 2016-03-07Clinical Trial Update: AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors [Phase 1]
Phase 1 study of AZD2171 (cediranib) in children with recurrent, progressive, or refractory primary central nervous system tumors has comple…
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CLINICAL_TRIALS trial_result · 2015-12-24Clinical Trial Update: Chemotherapy Combined With Radiation Therapy for Newly Diagnosed CNS AT/RT [Phase 2]
Phase 2 trial evaluating chemotherapy combined with radiation therapy for newly diagnosed atypical teratoid/rhabdoid tumor of the central ne…
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CLINICAL_TRIALS trial_result · 2014-11-05Clinical Trial Update: Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia [Phase 1]
Phase 1 study of RO4929097, a gamma-secretase inhibitor, in pediatric patients with relapsed or refractory solid tumors, CNS tumors, lymphom…
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CLINICAL_TRIALS trial_result · 2014-06-17Clinical Trial Update: Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia [Phase 1]
Phase 1 study evaluating vorinostat with or without isotretinoin in pediatric patients with recurrent or refractory solid tumors, lymphoma, …
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CLINICAL_TRIALS trial_result · 2014-02-27Clinical Trial Update: Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor [Phase 3]
Phase 3 clinical trial evaluating treatment for newly diagnosed medulloblastoma, supratentorial PNET, or atypical teratoid rhabdoid tumor; s…
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CLINICAL_TRIALS trial_result · 2013-09-30Clinical Trial Update: Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors [Phase 1]
A Phase 1 clinical trial evaluated lenalidomide in young patients with recurrent, progressive, or refractory central nervous system tumors. …
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CLINICAL_TRIALS trial_result · 2013-05-03Clinical Trial Update: Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors [Phase 1]
Phase 1 evaluation of vorinostat in combination with temozolomide in children with relapsed or refractory primary brain tumors or spinal cor…
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CLINICAL_TRIALS trial_result · 2009-10-15Clinical Trial Update: Oxaliplatin in Treating Children With Recurrent or Refractory Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor [Phase 2]
A Phase 2 clinical trial evaluating oxaliplatin in children with recurrent or refractory medulloblastoma, supratentorial primitive neuroecto…