Anaplastic Astrocytoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-11-09Clinical Trial Update: A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas [Phase 1]
Phase 1 feasibility trial evaluating oral 5-fluorocytosine in combination with genetically modified neural stem cells expressing E. coli cyt…
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CLINICAL_TRIALS trial_result · 2017-08-07Clinical Trial Update: p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors [Phase 1]
This Phase 1 trial tests the safety of the p28 peptide in younger patients with recurrent or progressive central nervous system tumors and t…
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CLINICAL_TRIALS trial_result · 2017-07-13Clinical Trial Update: Erlotinib in Treating Patients With Recurrent Malignant Glioma or Recurrent or Progressive Meningioma [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating erlotinib in adults with recurrent malignant glioma or recurrent/progressive meningioma; the study is co…
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CLINICAL_TRIALS research · 2017-06-08Clinical Trial Update: The Efficacy of APT Magnetic Resonance Imaging in Predicting the Efficacy of Bevacizumab in Recurrent Malignant Gliomas
This document reports an update on using APT MRI to predict Bevacizumab efficacy in patients with recurrent malignant gliomas; the trial sta…
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Stem Cell Radiotherapy and Temozolomide for Newly Diagnosed High-grade Glioma [NA]
A terminated clinical trial evaluating stem cell radiotherapy with temozolomide for newly diagnosed high-grade glioma has posted results.
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Bendamustine Hydrochloride in Treating Patients With Recurrent or Progressive Anaplastic Glioma [Phase 2]
Phase 2 trial of bendamustine hydrochloride in adults with recurrent or progressive anaplastic glioma has completed and results have been po…
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Efficacy and Safety of Temodal vs Semustine in Subjects With Recurrent Glioblastoma or Anaplastic Astrocytoma (Study P03644) [Phase 3]
Phase 3 trial results update comparing Temodal (temozolomide) with semustine in recurrent glioblastoma and anaplastic astrocytoma has been c…
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: SCH 52365 Phase II Clinical Study: A Study on the Efficacy and Safety of Monotherapy With SCH 52365 in Patients With First Relapsed Anaplastic Astrocytoma (Study P03745) [Phase 2]
Phase II monotherapy trial of SCH 52365 for first-relapsed anaplastic astrocytoma has completed; the snippet does not provide efficacy or sa…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: A Phase I/II Trial of BMS-247550 for Treatment of Patients With Recurrent High-Grade Gliomas [Phase 1, Phase 2]
Results from a Phase I/II trial of BMS-247550 for recurrent high-grade gliomas have been posted, evaluating adults with anaplastic astrocyto…
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FDA approval · 2017-04-26FDA Approved: TEMOZOLOMIDE — Original Application (CivicaScript LLC)
FDA approved Temozolomide under CivicaScript LLC's original application (ANDA207658), marking the approval of a generic Temozolomide product…
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: 3T MRI Biomarkers of Glioma Treatment Response [EARLY_Phase 1]
An early-phase 1 trial evaluating 3T MRI biomarkers for glioma treatment response, sponsored by Vanderbilt-Ingram Cancer Center, has been te…
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma [EARLY_Phase 1]
An early Phase 1 trial of topotecan delivered via convection-enhanced delivery for high-grade glioma (WHO Grade III or IV) has completed.
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CLINICAL_TRIALS trial_result · 2017-03-27Clinical Trial Update: Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases [NA]
A clinical trial comparing gadobutrol to gadopentetate dimeglumine or gadobenate dimeglumine before DCE-MRI in patients with multiple sclero…
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CLINICAL_TRIALS trial_result · 2017-03-20Clinical Trial Update: 18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas [NA]
Terminated trial evaluating 18F-FDOPA PET/CT or PET/MRI for measuring tumors in patients with newly diagnosed or recurrent gliomas; results …
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FDA approval · 2017-02-27FDA Approved: TEMOZOLOMIDE — Original Application (Accord Healthcare Inc.)
FDA approved an original application for temozolomide by Accord Healthcare Inc., authorizing a generic version of the cancer drug temozolomi…
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma [Phase 1]
Phase 1 clinical trial evaluating a vaccine therapy in combination with sargramostim (GM-CSF) for malignant glioma, including several glioma…
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FDA approval · 2017-02-24FDA Approved: TEMODAR — Supplemental Application (Merck Sharp & Dohme LLC)
FDA approved a supplemental application for Temodar (temozolomide) filed by Merck Sharp & Dohme LLC. The action updates Temodar's labeling t…
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CLINICAL_TRIALS trial_result · 2017-02-20Clinical Trial Update: Antineoplaston Therapy in Treating Adult Patients With Anaplastic Astrocytoma [Phase 2]
Phase 2 clinical trial updates on antineoplaston therapy for adults with anaplastic astrocytoma; results have been posted.
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CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors [Phase 1]
Phase 1 clinical trial evaluating aminolevulinic acid during surgery for malignant brain tumors; the study was terminated.
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Super-Selective Intraarterial Cerebral Infusion of Cetuximab (Erbitux) for Treatment of Relapsed/Refractory GBM and AA [Phase 1]
A Phase 1 clinical trial evaluating super-selective intraarterial infusion of cetuximab (Erbitux) for relapsed/refractory glioblastoma and a…
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CLINICAL_TRIALS trial_result · 2017-01-13Clinical Trial Update: Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas [Phase 2]
Phase 2 clinical trial evaluating radiation therapy with temozolomide and lomustine in young patients with newly diagnosed gliomas; complete…
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: Antineoplaston Therapy in Treating Patients With Anaplastic Astrocytoma [Phase 2]
Phase 2 clinical trial results for antineoplaston therapy in patients with anaplastic astrocytoma, sponsored by the Burzynski Research Insti…
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: The Effect of Radiotherapy and Temozolomide on the Tumor Vasculature and Stem Cells in Human High-grade Astrocytomas
The clinical trial evaluating the effects of radiotherapy and temozolomide on tumor vasculature and cancer stem cells in high-grade astrocyt…
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: FR901228 in Treating Patients With Recurrent High-Grade Gliomas [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluated FR901228 in adults with recurrent high-grade gliomas; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating an NY-ESO-1 vaccine therapy with or without sirolimus in patients whose tumors express NY-ESO-1.