Anaplastic Astrocytoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-07-14Clinical Trial Update: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Anaplastic Astrocytoma [Phase 2]
A Phase 2 clinical trial update evaluating the combination of chemotherapy and radiation therapy for patients with anaplastic astrocytoma.
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CLINICAL_TRIALS other · 2016-06-07Clinical Trial Update: Expanded Access to ANG1005 for Individual Patients
Expanded access program for ANG1005 (Angiochem) for individual patients with several brain cancers; the program is no longer available.
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CLINICAL_TRIALS trial_result · 2016-05-30Clinical Trial Update: Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery [Phase 1]
This clinical trial update reports on a Phase 1 study of the oncolytic herpes simplex virus HSV-1716 in children with refractory or recurren…
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CLINICAL_TRIALS trial_result · 2016-05-27Clinical Trial Update: Cellular Immunotherapy Study for Brain Cancer [Phase 1]
Phase 1 clinical trial update describes completion of a cellular immunotherapy study for brain tumors to assess safety and initial signals o…
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FDA approval · 2016-04-28FDA Approved: CARMUSTINE — Supplemental Application (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.)
The FDA approved a supplemental application for Carmustine submitted by Heritage Pharmaceuticals Inc. (doing business as Avet Pharmaceutical…
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma [Phase 1]
Phase 1 trial evaluating temozolomide with radiation therapy for newly diagnosed glioblastoma and anaplastic astrocytoma; results have been …
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FDA approval · 2016-04-27FDA Approved: TEMOZOLOMIDE — Original Application (Rising Pharma Holdings, Inc.)
FDA approved the original application for temozolomide in a generic form, enabling Rising Pharma Holdings, Inc. to market temozolomide.
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CLINICAL_TRIALS trial_result · 2016-04-18Clinical Trial Update: Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma [Phase 1, Phase 2]
Clinical trial update for Temsirolimus and Perifosine in recurrent or progressive malignant glioma (Phase 1/2) with completed status and pos…
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CLINICAL_TRIALS trial_result · 2016-04-15Clinical Trial Update: AMG 595 First-in-Human in Recurrent Gliomas [Phase 1]
Amgen completed a first-in-human Phase 1 trial of AMG 595 in recurrent gliomas to assess safety and early signals of activity. The study inc…
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CLINICAL_TRIALS trial_result · 2016-03-29Clinical Trial Update: A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade Gliomas [Phase 2]
Results from a Phase II randomized trial in adults with recurrent high-grade gliomas comparing vandetanib with carboplatin followed by vande…
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CLINICAL_TRIALS trial_result · 2016-03-07Clinical Trial Update: AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors [Phase 1]
Phase 1 study of AZD2171 (cediranib) in children with recurrent, progressive, or refractory primary central nervous system tumors has comple…
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CLINICAL_TRIALS trial_result · 2016-02-29Clinical Trial Update: Sunitinib in Treating Patients With Recurrent Malignant Gliomas [Phase 2]
Phase 2 trial evaluating sunitinib for adults with recurrent malignant gliomas has completed; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-02-10Clinical Trial Update: Oral Tarceva Study for Recurrent/Residual Glioblastoma Multiforme and Anaplastic Astrocytoma [Phase 1, Phase 2]
This update reports results from a Phase 1/2 trial of Tarceva (erlotinib) for recurrent/residual glioblastoma multiforme and anaplastic astr…
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CLINICAL_TRIALS trial_result · 2015-10-02Clinical Trial Update: VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide [Phase 2]
Phase 2 trial evaluating aflibercept (VEGF Trap) for recurrent malignant gliomas unresponsive to temozolomide has completed; results were po…
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CLINICAL_TRIALS trial_result · 2015-09-29Clinical Trial Update: RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma [Phase 1]
This Phase 1 trial assessed RO4929097 in combination with temozolomide and radiation therapy for newly diagnosed malignant glioma and has co…
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FDA approval · 2015-09-18FDA Approved: TEMODAR — Supplemental Application (Merck Sharp & Dohme LLC)
The FDA approved a supplemental application for TEMODAR (temozolomide) submitted by Merck Sharp & Dohme LLC.
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FDA approval · 2015-09-18FDA Approved: TEMODAR — Supplemental Application (Merck Sharp & Dohme LLC)
FDA approved a supplemental application for TEMODAR (temozolomide) submitted by Merck Sharp & Dohme LLC. The action updates the drug's label…
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CLINICAL_TRIALS trial_result · 2015-07-14Clinical Trial Update: RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma [Phase 1, Phase 2]
Phase 1/2 trial evaluating RO4929097 in combination with Bevacizumab for progressive or recurrent malignant glioma was terminated; results w…
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CLINICAL_TRIALS trial_result · 2015-06-15Clinical Trial Update: Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma [Phase 1, Phase 2]
This entry reports the completion and posted results of a Phase 1/2 trial evaluating erlotinib in combination with temsirolimus for recurren…
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: A Study of PD 0332991 in Patients With Recurrent Rb Positive Glioblastoma [Phase 2]
A Phase 2 study of Palbociclib (PD-0332991) in recurrent RB-positive glioblastoma was terminated. Results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma [Phase 2]
A Phase II trial of NKTR-102 in bevacizumab-resistant high-grade glioma has completed, with results posted in 2015, evaluating activity in a…
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FDA approval · 2015-06-10FDA Approved: TEMOZOLOMIDE — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
FDA approves a supplemental application for temozolomide from Sun Pharmaceutical Industries, Inc., under ANDA201742, granting a supplemental…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2 [Phase 1]
Phase I trial evaluating intratumoral GRm13Z40-2 T-cell therapy (genetically modified allogeneic CD8+ T cells expressing IL-13-Zetakine and …
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CLINICAL_TRIALS withdrawal · 2015-05-22Clinical Trial Update: Valproic Acid in Childhood Progressive Brain Tumors [Phase 1]
The trial withdrawal notice states that the Phase 1 study of valproic acid for childhood progressive brain tumors has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-05-12Clinical Trial Update: Re-irradiation of High Grade Gliomas: a Quality of Life Study
A clinical trial studying re-irradiation for high-grade gliomas with a quality-of-life focus has been withdrawn.