Anaplastic Astrocytoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas [Phase 1]
Phase 1 clinical trial update exploring vorinostat with temozolomide for malignant gliomas in adults, with active-not-recruiting status acro…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Pediatric Long-Term Follow-up and Rollover Study [Phase 4]
Pediatric long-term follow-up and rollover study (Phase 4) sponsored by Novartis is active but not recruiting, tracking outcomes in children…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Comprehensive Analysis of Chemotherapy and Targeted Therapy Outcomes in Recurrent Malignant Gliomas
This clinical trial update reports a comprehensive analysis of chemotherapy and targeted therapy outcomes in recurrent malignant gliomas, in…
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Clinical Trial Evaluating Safety of 5-Aminolevulinic Acid (5-ALA) Combined With CV01 Delivery of Ultrasound for Sonodynamic Therapy (SDT) in Patients With Newly Diagnosed High-Grade Glioma (HGG) Prior to Resection and Standard Adjuvant Therapy (ALA SDT GLIOMA 401) [Phase 1]
A Phase 1 trial evaluating the safety of combining 5-ALA with the CV01 ultrasound delivery system for sonodynamic therapy in patients with n…
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CLINICAL_TRIALS trial_result · 2026-01-22Clinical Trial Update: Re-Administration of C134 in Patients With Recurrent GBM (C134-HSV-1) [Phase 1]
Phase 1 study evaluating re-administration of C134 in patients with recurrent glioblastoma and related brain gliomas has been terminated.
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Multi-kinase Inhibitor TG02 (TG02) in Elderly Newly Diagnosed or Adult Relapsed Patients With Anaplastic Astrocytoma or Glioblastoma. [Phase 1]
Phase 1 trial of the multi-kinase inhibitor TG02 in elderly newly diagnosed or adult relapsed patients with anaplastic astrocytoma or gliobl…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Evaluating the Expression Levels of MicroRNA-10b in Patients With Gliomas
The clinical trial investigating microRNA-10b expression in glioma patients has been terminated.
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CLINICAL_TRIALS trial_result · 2025-09-02Clinical Trial Update: Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma [EARLY_Phase 1]
Early-phase study evaluating the use of 18F-FDOPA PET imaging to plan surgery and radiation therapy for adults with newly diagnosed malignan…
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CLINICAL_TRIALS trial_result · 2025-07-16Clinical Trial Update: Study Of NOVOTTF-200A In Bevacizumab-Naive Subjects With Recurrent Grade III Malignant Astrocytoma [NA]
Results posted for a study of NOVOTTF-200A in bevacizumab-naive subjects with recurrent grade III malignant astrocytoma.
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma [Phase 2]
Phase 2 trial comparing proton beam therapy with intensity-modulated radiation therapy for preserving brain function in IDH-mutant grade II/…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Trial of C134 in Patients With Recurrent GBM [Phase 1]
Phase 1 clinical trial update for C134 in recurrent glioblastoma and related brain cancers reports results with results posted on 2025-07-03…
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CLINICAL_TRIALS trial_result · 2025-04-09Clinical Trial Update: Repeated Super-selective Intraarterial Cerebral Infusion Of Bevacizumab Plus Carboplatin For Treatment Of Relapsed/Refractory GBM And Anaplastic Astrocytoma [Phase 1, Phase 2]
A Phase 1/2 trial of repeated super-selective intraarterial bevacizumab plus carboplatin for relapsed/refractory glioblastoma multiforme and…
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CLINICAL_TRIALS trial_result · 2025-02-21Clinical Trial Update: Studying the Safety, Efficacy, and Pharmacokinetic Characteristics of BNCT in Patients With Recurrent High-grade Gliomas [Phase 1, Phase 2]
A terminated Phase 1/2 trial evaluated the safety, efficacy, and pharmacokinetics of boron neutron capture therapy (BNCT) for recurrent high…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas [Phase 1]
Phase 1 trial of INCB7839 in children with recurrent or progressive high-grade gliomas has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma [Phase 1]
A Phase 1 trial evaluating Lapatinib Ditosylate before surgical resection in adults with recurrent high-grade glioma has completed. The stud…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Dendritic Cell Vaccine for Patients With Brain Tumors [Phase 2]
Phase 2 trial of an autologous dendritic cell vaccine for brain tumors has completed enrollment and assessment.
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors [Phase 2]
Phase 2 pediatric brain tumor trial evaluating MRI-guided laser heat ablation to disrupt the peritumoral blood-brain barrier in order to imp…
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas [Phase 1, Phase 2]
A Phase I/Phase II study evaluating mebendazole for pediatric gliomas has completed. It enrolled children with various glial tumors, includi…
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma [Phase 1]
Phase 1 study of CC-90010 assesses CNS penetration, pharmacokinetics, and pharmacodynamics in progressive/recurrent diffuse astrocytoma, ana…
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors [Phase 1]
The SJDAWN Phase 1 trial at St. Jude evaluated molecularly-driven doublet therapies for children and young adults with recurrent brain tumor…
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Carboxylesterase-Expressing Allogeneic Neural Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas [Phase 1]
Phase 1 clinical trial update evaluating safety and preliminary efficacy of carboxylesterase-expressing allogeneic neural stem cells in comb…
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations [Phase 2]
Phase 2 clinical trial evaluating veliparib in combination with radiation therapy and temozolomide for newly diagnosed malignant glioma; res…
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CLINICAL_TRIALS trial_result · 2024-04-08Clinical Trial Update: Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children [Phase 1]
Phase 1b trial update for PVSRIPO in recurrent malignant glioma in children has completed enrollment and results posted.
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Glioma [Phase 2]
Phase 2a study of CAN-2409 with standard radiation therapy in malignant glioma (including glioblastoma multiforme) has completed; results po…
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGG [Phase 2]
A Phase 2 study of the MEK inhibitor binimetinib plus the BRAF inhibitor encorafenib in adults with recurrent BRAF V600-mutant high-grade gl…