Amyotrophic Lateral Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-08-18Clinical Trial Update: Low Dose IL-2 in the Treatment of Immune-associated ALS Syndrome [Phase 2]
Phase 2 trial evaluating low-dose interleukin-2 for immune-associated amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2021-08-16Clinical Trial Update: Open-Label, Safety and Tolerability Extension Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) (CL211) [Phase 2]
Phase 2 open-label extension study assessing safety and tolerability of KNS-760704 in amyotrophic lateral sclerosis completed with results p…
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FDA approval · 2021-08-13FDA Approved: RILUZOLE — Supplemental Application (Ascend Laboratories, LLC)
FDA approved a supplemental application for riluzole submitted by Ascend Laboratories, LLC, updating the approved riluzole product.
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CLINICAL_TRIALS trial_result · 2021-08-11Clinical Trial Update: AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 trial of AMX0035 in amyotrophic lateral sclerosis completed; results were posted in August 2021.
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CLINICAL_TRIALS trial_result · 2021-07-08Clinical Trial Update: The Treatment of Amyotrophic Lateral Sclerosis With Huollingshengji Granules [Phase 2, Phase 3]
Phase 2/3 trial update for Huollingshengji granules in amyotrophic lateral sclerosis is reported, with current status unknown.
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CLINICAL_TRIALS trial_result · 2021-07-08Clinical Trial Update: Safety and Tolerability Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 safety and tolerability study of KNS-760704 in amyotrophic lateral sclerosis (ALS) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-07-06Clinical Trial Update: Efficacy and Safety of Nitrazine in the Treatment of ALS [Phase 2]
Phase 2 clinical trial update on Nitrazine for amyotrophic lateral sclerosis, reporting on efficacy and safety.
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CLINICAL_TRIALS trial_result · 2021-06-07Clinical Trial Update: Phase 3 Study of Dexpramipexole in ALS [Phase 3]
A Phase 3 trial of dextramipexole for amyotrophic lateral sclerosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-05-12Clinical Trial Update: A Study for Patients Who Completed VITALITY-ALS (CY 4031) [Phase 3]
Phase 3 trial update for patients who completed VITALITY-ALS (CY 4031); study completed with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-05-05Clinical Trial Update: Efficacy and Safety of Plasma Exchange With Albutein® 5% in Participants With Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 trial assessing plasma exchange with Albutein 5% for efficacy and safety in amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2021-04-27Clinical Trial Update: GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS) [Phase 2]
Phase 2A randomized, double-blind, placebo-controlled pilot trial of GM604 in amyotrophic lateral sclerosis completed.
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CLINICAL_TRIALS trial_result · 2021-04-19Clinical Trial Update: Clinical Trial on the Use of Cell Therapy in the Treatment of Patients With Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 clinical trial investigating cell therapy for Amyotrophic Lateral Sclerosis.
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CLINICAL_TRIALS trial_result · 2021-03-29Clinical Trial Update: Repeated Mesenchymal Stem Cell Injections in ALS [Phase 1, Phase 2]
A Phase 1/2 trial evaluating repeated mesenchymal stem cell injections in adults with amyotrophic lateral sclerosis has completed.
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FDA approval · 2021-03-15FDA Approved: RADICAVA — Supplemental Application (Shionogi Inc.)
The FDA approved a supplemental application for RADICAVA (edaravone) from Shionogi Inc., marking an additional regulatory approval for the p…
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CLINICAL_TRIALS trial_result · 2021-03-08Clinical Trial Update: Pharyngeal Electrical Stimulation in Amyotrophic Lateral Sclerosis [Phase 1, Phase 2]
Phase 1/2 trial update on pharyngeal electrical stimulation for amyotrophic lateral sclerosis (ALS).
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CLINICAL_TRIALS trial_result · 2021-03-03Clinical Trial Update: Open Label Study to Evaluate Ciprofloxacin/Celecoxib Combination in Patients With ALS [Phase 2]
Phase 2 open-label trial evaluating a ciprofloxacin/celecoxib combination in patients with amyotrophic lateral sclerosis (ALS) has completed…
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CLINICAL_TRIALS trial_result · 2021-03-03Clinical Trial Update: A Pilot Study of RNS60 in Amyotrophic Lateral Sclerosis (ALS) [Phase 1]
A Phase 1 pilot study of RNS60 in amyotrophic lateral sclerosis (ALS) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-02-18Clinical Trial Update: Safety of Urate Elevation in Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 clinical trial assessing safety of elevating urate levels in amyotrophic lateral sclerosis (ALS).
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CLINICAL_TRIALS trial_result · 2021-01-15Clinical Trial Update: A Study to Evaluate Transplantation of Astrocytes Derived From Human Embryonic Stem Cells, in Patients With Amyotrophic Lateral Sclerosis (ALS) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating transplantation of astrocytes derived from human embryonic stem cells in ALS patients has completed recr…
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CLINICAL_TRIALS trial_result · 2021-01-15Clinical Trial Update: Perampanel for Sporadic Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 clinical trial update for perampanel in sporadic amyotrophic lateral sclerosis (ALS) has been completed.
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CLINICAL_TRIALS trial_result · 2020-11-27Clinical Trial Update: Effect of Noninvasive Ventilation on Lung Function in Amyotrophic Lateral Sclerosis [NA]
Clinical trial on noninvasive ventilation and lung function in Amyotrophic Lateral Sclerosis has been terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-10-30Clinical Trial Update: A Multi-Center Controlled Screening Trial of Safety and Efficacy of Lithium Carbonate in Subjects With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
A Phase 2 multicenter trial evaluating safety and efficacy of lithium carbonate in subjects with Amyotrophic Lateral Sclerosis has completed…
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CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: The Safety and Effectiveness of Cholinergic Receptor Block Therapy in the Treatment of ALS [Phase 2]
Phase 2 trial update evaluating cholinergic receptor block therapy for safety and effectiveness in amyotrophic lateral sclerosis with respir…
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CLINICAL_TRIALS trial_result · 2020-09-23Clinical Trial Update: Safety and Biomarker Study of EPI-589 in Participants With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 safety and biomarker trial of EPI-589 in participants with amyotrophic lateral sclerosis completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-09-11Clinical Trial Update: A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 trial evaluating CK-2127107 in amyotrophic lateral sclerosis (ALS) has completed with results posted.