Amyotrophic Lateral Sclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-03-03Clinical Trial Update: Open Label Extension of TUDCA-ALS Study [Phase 3]
Open-label extension update for a Phase 3 TUDCA-ALS trial investigating amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2023-03-01Clinical Trial Update: Colchicine for Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 clinical trial investigating colchicine for amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2023-01-10Clinical Trial Update: An Efficacy and Safety Study of Ravulizumab in ALS Participants [Phase 3]
Phase 3 trial evaluating ravulizumab in Amyotrophic Lateral Sclerosis (ALS) was terminated; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2022-11-29Clinical Trial Update: Therapy in Amyotrophic Lateral Sclerosis (TAME) [Phase 2]
Phase 2 trial update for a therapy in amyotrophic lateral sclerosis and frontotemporal dementia; trial completed with results posted in 2022…
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CLINICAL_TRIALS trial_result · 2022-10-25Clinical Trial Update: Cervical Electrical Stimulation for ALS [NA]
A completed clinical trial assessing cervical electrical stimulation for amyotrophic lateral sclerosis; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-09-06Clinical Trial Update: Clenbuterol on Motor Function in Individuals With Amyotrophic Lateral Sclerosis [Phase 2]
A Phase 2 clinical trial evaluating clenbuterol for motor function in individuals with amyotrophic lateral sclerosis has completed and poste…
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CLINICAL_TRIALS trial_result · 2022-08-29Clinical Trial Update: Safety Study of Oral Edaravone Administered in Subjects With ALS [Phase 3]
Phase 3 safety study of oral edaravone in people with amyotrophic lateral sclerosis has completed and results are posted.
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FDA approval · 2022-08-02FDA Approved: RILUZOLE — Supplemental Application (Glenmark Pharmaceuticals Inc., USA)
The FDA approved a supplemental application for riluzole submitted by Glenmark Pharmaceuticals Inc., USA.
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CLINICAL_TRIALS trial_result · 2022-07-14Clinical Trial Update: Physiological Flow of Liquids Used in Dysphagia Management (Neuro)
Completed clinical trial evaluating physiological flow of liquids used in dysphagia management in ALS and Parkinson disease patients; result…
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CLINICAL_TRIALS trial_result · 2022-06-21Clinical Trial Update: Transmembrane Electromyography (TM-EMG) for the Assessment of Neuromuscular Function in the Oropharynx [NA]
A completed clinical trial evaluating Transmembrane Electromyography (TM-EMG) for assessing neuromuscular function in the oropharynx with re…
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CLINICAL_TRIALS trial_result · 2022-06-06Clinical Trial Update: NF-κB Inhibition in Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 clinical trial exploring NF-κB inhibition as a potential therapy for amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2022-06-02Clinical Trial Update: Outcomes Mandate National Integration With Cannabis as Medicine [Phase 2]
Phase 2 clinical trial update focusing on integrating cannabis as medicine for various chronic pain conditions, with status currently UNKNOW…
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FDA approval · 2022-05-12FDA Approved: RADICAVA ORS — Original Application (Shionogi Inc.)
The FDA approved RADICAVA ORS (edaravone) for use as an oral suspension under an Original Application by Shionogi Inc., adding an oral formu…
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CLINICAL_TRIALS trial_result · 2022-05-03Clinical Trial Update: The Evaluation of the Effect of Mesenchymal Stem Cells on the Immune System of Patients With ALS [Phase 1, Phase 2]
A clinical trial evaluating mesenchymal stem cells for the immune system in patients with amyotrophic lateral sclerosis (ALS) across Phase 1…
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CLINICAL_TRIALS trial_result · 2022-04-21Clinical Trial Update: Supported Treadmill Ambulation Training (STAT) for Patients Diagnosed With Amyotrophic Lateral Aclerosis [Phase 1, Phase 2]
Phase 1/2 trial investigating Supported Treadmill Ambulation Training (STAT) for patients with amyotrophic lateral sclerosis (ALS).
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CLINICAL_TRIALS trial_result · 2022-04-07Clinical Trial Update: Phase 3 Extension Study of Dexpramipexole in ALS [Phase 3]
Phase 3 extension study update for dexpramipexole in ALS; study terminated with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-04-06Clinical Trial Update: A Multicenter Phase I/II Clinical Trial to Evaluate Safety of Mesenchymal Stem Cell in Patients With Amyotrophic Sclerosis Lateral [Phase 1, Phase 2]
A multicenter Phase I/II trial evaluating the safety of mesenchymal stem cells in patients with amyotrophic lateral sclerosis has completed.
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CLINICAL_TRIALS trial_result · 2022-02-17Clinical Trial Update: Treatment Continuation Study for Patients With ALS/MND Who Completed Study CMD-2019-001 [Phase 2]
Phase 2 treatment continuation study for ALS/MND patients who completed CMD-2019-001 has completed.
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CLINICAL_TRIALS trial_result · 2022-02-17Clinical Trial Update: ALS Treatment Extension Study [Phase 1, Phase 2]
Clinical trial update for an ALS treatment extension study spanning Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2021-11-05Clinical Trial Update: Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 clinical trial update for ibudilast (MN-166) in subjects with amyotrophic lateral sclerosis has completed and results posted.
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CLINICAL_TRIALS trial_result · 2021-11-04Clinical Trial Update: ALS and Airway Clearance (ALSAC) Therapy [NA]
Completed clinical trial investigating ALS and airway clearance therapy (ALSAC) for amyotrophic lateral sclerosis with respiratory muscle we…
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CLINICAL_TRIALS trial_result · 2021-10-20Clinical Trial Update: Clinical Trial of Glatiramer Acetate in Amyotrophic Lateral Sclerosis (ALS) [Phase 2]
Phase 2 trial of glatiramer acetate in amyotrophic lateral sclerosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-10-06Clinical Trial Update: T-regulatory Cells in ALS [Phase 2]
Phase 2 clinical trial update investigating T-regulatory cells in Amyotrophic Lateral Sclerosis is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2021-09-01Clinical Trial Update: Safety and Tolerability of High Dose Biotin in Patients With Amyotrophic Lateral Sclerosis [Phase 2]
Phase 2 clinical trial update on safety and tolerability of high-dose biotin in patients with amyotrophic lateral sclerosis.
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CLINICAL_TRIALS trial_result · 2021-08-31Clinical Trial Update: Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALS [Phase 3]
Phase 3 trial investigating oral levosimendan (ODM-109) for respiratory function in amyotrophic lateral sclerosis has completed with results…