Amyotrophic Lateral Sclerosis
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Transcranial Static Magnetic Stimulation (tSMS) and Potential Theranostic Biomarkers in Amyotrophic Lateral Sclerosis. [NA]
A registered clinical trial investigating transcranial static magnetic stimulation and potential theranostic biomarkers for amyotrophic late…
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: Novel MRI Biomarkers for Monitoring Disease Progression in ALS
University of Alberta is recruiting for a clinical study evaluating novel MRI biomarkers to monitor disease progression in amyotrophic later…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Measurement and Impact of Physical Impairment in Amyotrophic Lateral Sclerosis: Use of Digital Technologies - A Precision ALS Project
This clinical trial update describes the Precision ALS project, which uses digital technologies to measure physical impairment in amyotrophi…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Individualized Functional Imaging-Guided Repetitive Transcranial Magnetic Stimulation (rTMS) for Treating Postural Gait Disorders in Patients with Amyotrophic Lateral Sclerosis (ALS): a Randomized, Crossover, Controlled, Double-Blind Clinical Study [EARLY_Phase 1]
A Phase 1 randomized, crossover, double-blind trial is evaluating individualized functional imaging-guided repetitive transcranial magnetic …
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Augmented Reality BCI Longitudinal Study for Persons With Late Stage ALS [NA]
Cognixion is conducting a longitudinal study of an augmented reality brain-computer interface for people with late-stage amyotrophic lateral…
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CLINICAL_TRIALS research · 2025-02-04Clinical Trial Update: Genetics and Environment iNtersection In the ALS-FTD Spectrum: an Italian Twins Cohort studY With a Multi-Omics Approach
This study investigates genetic and environmental factors in the amyotrophic lateral sclerosis and frontotemporal dementia spectrum using a …
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Clinical Characteristics, Natural History, Health Care Measures, and Genetic Screening in Patients With ALS
Completed clinical trial update describing clinical characteristics, natural history, health care measures, and genetic screening in patient…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Registry Study of Assistive Devices, Medicines and Healthcare Measures in ALS, SMA and Other Neurological Diseases.
A registry study evaluating assistive devices, medicines, and healthcare measures for amyotrophic lateral sclerosis, spinal muscular atrophy…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: Structural and Functional Networks in ALS: An Insight Into Pseudobulbar Affect [NA]
Clinical trial investigating structural and functional brain networks in amyotrophic lateral sclerosis and pseudobulbar affect. The study is…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Safety and Dosimetry of a New Radiotracer to Detect Misfolded SOD1 Associated With Amyotrophic Lateral Sclerosis [Phase 1]
This clinical trial update describes a Phase 1 study evaluating the safety and dosimetry of a new radiotracer intended to detect misfolded S…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Psilocybin Therapy for Psychological Distress in Palliative Patients [Phase 2]
Phase 2 trial update on psilocybin therapy for psychological distress in palliative patients; status is not yet recruiting.
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of FHND1002 Granules in Healthy Adults [Phase 1]
Phase 1 clinical trial update for FHND1002 Granules assessing safety, tolerability, and pharmacokinetics in healthy adults, with amyotrophic…
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications [NA]
A Penn State University clinical trial is currently recruiting to evaluate verbal communication in structured interactions for individuals w…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Clinical Study of Induced Pluripotent Stem Cells Derived Motor Neuron Precursor Cell Therapy for Amyotrophic Lateral Sclerosis (ALS) [NA]
A recruiting clinical trial is evaluating an induced pluripotent stem cell–derived motor neuron precursor cell therapy for amyotrophic later…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Genetic Study of Amyotrophic Lateral Sclerosis in Norway
A genetic study of amyotrophic lateral sclerosis in Norway is currently recruiting participants, sponsored by Sykehuset Telemark.
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RAG-17 in Subjects With Amyotrophic Lateral Sclerosis (ALS) With Superoxide Dismutase Type 1 (SOD1) Gene Mutation [Phase 1]
Phase 1 clinical trial evaluating safety, tolerability, pharmacokinetics, and pharmacodynamics of RAG-17 in Amyotrophic Lateral Sclerosis pa…
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: TP04HN106 in the Treatment of Patients With Amyotrophic Lateral Sclerosis [Phase 1, Phase 2]
A clinical trial update for TP04HN106 in amyotrophic lateral sclerosis, a Phase 1/Phase 2 study that is currently recruiting.
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases
A clinical trial update reports completion of a genetics study on pediatric-onset motor neuron and neuromuscular diseases, including spinal …
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Proteinopathies Expression in Skin of Neurodegenerative Disorders
Clinical trial examining skin expression of proteinopathies in several neurodegenerative diseases; currently recruiting and led by Universid…
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Ultra-high-caloric, Fatty Diet in ALS [NA]
A clinical trial at the University of Ulm is evaluating an ultra-high-caloric, fatty diet in people with amyotrophic lateral sclerosis and i…
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: A Phase 1, SAD and MAD Study to Evaluate the Safety and Tolerability of FB418 [Phase 1]
Phase 1 study update for FB418 evaluating safety and tolerability in Parkinson disease and ALS; currently recruiting.
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Anticipated Patient and Caregiver Burden [NA]
A clinical trial update notes ongoing recruitment for an ALS study and discusses anticipated burden on patients and caregivers.
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: French-German Cohort Study to Determine Factors Associated With Weight Loss in Amyotrophic Lateral Sclerosis [NA]
This clinical trial update describes a French-German cohort study investigating factors associated with weight loss in amyotrophic lateral s…
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CLINICAL_TRIALS research · 2024-11-14Clinical Trial Update: FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases
FLOWER is a longitudinal epidemiology study by xCures to follow outcomes across multiple rare diseases, and the study is currently recruitin…
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Polish Version Fatigue Severity Scale
A Polish-version Fatigue Severity Scale trial is currently recruiting, sponsored by Jakub Antczak, involving patients with multiple sclerosi…